NO992063D0 - Benzoxazole derivative with affinity for binding sites at amino acid receptors - Google Patents

Benzoxazole derivative with affinity for binding sites at amino acid receptors

Info

Publication number
NO992063D0
NO992063D0 NO992063A NO992063A NO992063D0 NO 992063 D0 NO992063 D0 NO 992063D0 NO 992063 A NO992063 A NO 992063A NO 992063 A NO992063 A NO 992063A NO 992063 D0 NO992063 D0 NO 992063D0
Authority
NO
Norway
Prior art keywords
affinity
amino acid
binding sites
acid receptors
benzoxazole derivative
Prior art date
Application number
NO992063A
Other languages
Norwegian (no)
Other versions
NO992063L (en
Inventor
Cher Helmut Pr
Rudolf Gottschlich
Joachim Leibrock
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO992063D0 publication Critical patent/NO992063D0/en
Publication of NO992063L publication Critical patent/NO992063L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO992063A 1996-10-30 1999-04-29 Benzoxazole derivative with affinity for binding sites at amino acid receptors NO992063L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19643790A DE19643790A1 (en) 1996-10-30 1996-10-30 Benzoxazole derivative
PCT/EP1997/005590 WO1998018793A1 (en) 1996-10-30 1997-10-10 Benzoxazole derivative with an affinity to binding sites of amino acid receptors

Publications (2)

Publication Number Publication Date
NO992063D0 true NO992063D0 (en) 1999-04-29
NO992063L NO992063L (en) 1999-04-29

Family

ID=7809592

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992063A NO992063L (en) 1996-10-30 1999-04-29 Benzoxazole derivative with affinity for binding sites at amino acid receptors

Country Status (16)

Country Link
EP (1) EP0938485A1 (en)
JP (1) JP2001502713A (en)
KR (1) KR20000052876A (en)
CN (1) CN1235604A (en)
AR (1) AR008512A1 (en)
AU (1) AU4946597A (en)
BR (1) BR9712577A (en)
CA (1) CA2270359A1 (en)
CZ (1) CZ147999A3 (en)
DE (1) DE19643790A1 (en)
HU (1) HUP9904547A3 (en)
NO (1) NO992063L (en)
PL (1) PL332771A1 (en)
SK (1) SK53699A3 (en)
WO (1) WO1998018793A1 (en)
ZA (1) ZA979725B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
DE19812331A1 (en) * 1998-03-20 1999-09-23 Merck Patent Gmbh New benzo-heterocyclic substituted piperidine derivatives useful as excitatory aminoacid receptor antagonists, used e.g. for treating neurodegenerative diseases
PE20000728A1 (en) 1998-06-26 2000-08-21 Cocensys Inc HETEROCYCLES 4-BENZYL PIPERIDINE ALKYLSULFOXIDE AND THEIR USE AS SUBTYPE-SELECTIVE NMDA RECEPTOR ANTAGONISTS
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
EP1674087A1 (en) 2000-10-02 2006-06-28 Pfizer Products Inc. Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
DE10120159A1 (en) * 2001-04-25 2002-10-31 Merck Patent Gmbh NMDA antagonists and NMDA agonists for the treatment of addictions
ATE408611T1 (en) 2001-07-24 2008-10-15 Richter Gedeon Nyrt PIPERIDINES AS NMDA RECEPTOR ANTAGONISTS
DE102007047737A1 (en) * 2007-10-05 2009-04-30 Merck Patent Gmbh Piperidine and piperazine derivatives
DE102009049211A1 (en) 2009-10-13 2011-04-28 Merck Patent Gmbh sulfoxides
SG11201402472QA (en) 2011-11-22 2014-06-27 Univ California Cysteamine and/or cystamine for treating ischemic injury

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174915T1 (en) * 1994-10-31 1999-01-15 Merck Patent Gmbh BENZYLPIPERIDINE DERIVATIVES WITH HIGH AFFINITY FOR BINDING SITES OF AMINO ACID RECEPTORS

Also Published As

Publication number Publication date
CA2270359A1 (en) 1998-05-07
WO1998018793A1 (en) 1998-05-07
JP2001502713A (en) 2001-02-27
HUP9904547A3 (en) 2001-01-29
PL332771A1 (en) 1999-10-11
AU4946597A (en) 1998-05-22
CZ147999A3 (en) 1999-08-11
SK53699A3 (en) 2000-03-13
HUP9904547A2 (en) 2000-12-28
ZA979725B (en) 1998-05-22
NO992063L (en) 1999-04-29
AR008512A1 (en) 2000-01-19
CN1235604A (en) 1999-11-17
EP0938485A1 (en) 1999-09-01
DE19643790A1 (en) 1998-05-07
BR9712577A (en) 1999-10-19
KR20000052876A (en) 2000-08-25

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application