NO991558L - Meningococcal vaccine comprising the valence of strain BZ83 - Google Patents

Meningococcal vaccine comprising the valence of strain BZ83

Info

Publication number
NO991558L
NO991558L NO991558A NO991558A NO991558L NO 991558 L NO991558 L NO 991558L NO 991558 A NO991558 A NO 991558A NO 991558 A NO991558 A NO 991558A NO 991558 L NO991558 L NO 991558L
Authority
NO
Norway
Prior art keywords
strain
tbpb
formula
sequence encoding
dna sequence
Prior art date
Application number
NO991558A
Other languages
Norwegian (no)
Other versions
NO991558D0 (en
Inventor
Marie-Josu Quentin-Millet
Bachra Rokbi
Original Assignee
Pasteur Merieux Serums Vacc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serums Vacc filed Critical Pasteur Merieux Serums Vacc
Publication of NO991558D0 publication Critical patent/NO991558D0/en
Publication of NO991558L publication Critical patent/NO991558L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Oppfinnelsen vedrører en farmasøytisk sammensetning som omfatter (i) subenheten av minste molekylære vekt (TbpB) av human transferrinreseptor (HTR) av en Neisserie meningilis-slamme som har en DNA-sekvens kodende for Tbp, (a) som inneholder to av Avall restriksjonsseter, 3 Hinchll restriksjonsseter, ingen Vspl restriksjonssete og ingen Xhol restriksjonssete eller (b) fra hvor det er mulig å utvikle ved PCR (polymerase- kjedereaksjon) ved å bruke primere P3 fra formelen 5'-AAGACCAACK}CGGATACGGTTTTGC-3' og P4 fra formelen 5'-GAAGACGAGTCGGAAACAAAGGGATG-3\ et polynukleotid på 765 ti! 775 nukletodier. En slik stamme er for eksempel BZ83-stamme hvor DNA-sekvensen koder for TbpB er vist i SEQ ID NO: l.The invention relates to a pharmaceutical composition comprising (i) the small molecular weight subunit (TbpB) of human transferrin receptor (HTR) of a Neisserie meningilis slurry having a DNA sequence encoding Tbp, (a) containing two Avall restriction sites, 3 HinchII restriction sites, no Vspl restriction site and no XhoI restriction site or (b) from where it is possible to develop by PCR (polymerase chain reaction) using primers P3 of formula 5'-AAGACCAACK} CGGATACGGTTTTGC-3 'and P4 of formula 5 '-GAAGACGAGTCGGAAACAAAGGGATG-3 \ a polynucleotide of 765 ti! 775 nucleotides. One such strain is, for example, BZ83 strain where the DNA sequence encoding TbpB is shown in SEQ ID NO: 1.

NO991558A 1997-08-07 1999-03-30 Meningococcal vaccine comprising the valence of strain BZ83 NO991558L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9710301A FR2767060B1 (en) 1997-08-07 1997-08-07 MENINGOCOCCAL VACCINE WITH BZ83 STRAIN VALENCE
PCT/FR1998/001730 WO1999007741A1 (en) 1997-08-07 1998-08-03 Meningococcus vaccine comprising the valence of bz83 strain

Publications (2)

Publication Number Publication Date
NO991558D0 NO991558D0 (en) 1999-03-30
NO991558L true NO991558L (en) 1999-03-30

Family

ID=9510254

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991558A NO991558L (en) 1997-08-07 1999-03-30 Meningococcal vaccine comprising the valence of strain BZ83

Country Status (10)

Country Link
EP (1) EP0948534A1 (en)
JP (1) JP2001503068A (en)
CN (1) CN1241193A (en)
AU (1) AU8987598A (en)
CA (1) CA2267066A1 (en)
FR (1) FR2767060B1 (en)
HU (1) HUP0001451A3 (en)
NO (1) NO991558L (en)
NZ (1) NZ334992A (en)
WO (1) WO1999007741A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0107219D0 (en) * 2001-03-22 2001-05-16 Microbiological Res Authority Immunogenic commensal neisseria sequences
KR20160110368A (en) * 2013-12-02 2016-09-21 안토니 비. 쉬라이버스 Immunogenic compositions and vaccines derived from bacterial surface receptor proteins
US10232029B2 (en) 2014-12-09 2019-03-19 Sanofi Pasteur Compositions comprising N. meningitidis proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292869A (en) * 1989-04-27 1994-03-08 The Board Of Governors Of The University Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
FR2682041B1 (en) * 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins VACCINE AGAINST NEISSERIA MENINGITIDIS INFECTIONS.
FR2692592B1 (en) * 1992-06-19 1995-03-31 Pasteur Merieux Serums Vacc DNA fragments encoding the Neisseria meningitidis transferrin receptor subunits and methods of expressing them.
FR2720408B1 (en) * 1994-05-31 1996-08-14 Pasteur Merieux Serums Vacc Fragments Tbp2 of Neisseria meningitidis.
FR2739624B1 (en) * 1995-10-10 1997-12-05 Pasteur Merieux Serums Vacc NEW NEISSERIA MENINGITIDIS TBP2 SUBUNIT

Also Published As

Publication number Publication date
AU8987598A (en) 1999-03-01
NZ334992A (en) 2001-09-28
NO991558D0 (en) 1999-03-30
CA2267066A1 (en) 1999-02-18
HUP0001451A2 (en) 2001-04-28
CN1241193A (en) 2000-01-12
FR2767060B1 (en) 2000-02-11
JP2001503068A (en) 2001-03-06
EP0948534A1 (en) 1999-10-13
HUP0001451A3 (en) 2001-09-28
FR2767060A1 (en) 1999-02-12
WO1999007741A1 (en) 1999-02-18

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