NO980649L - Bioconjugates of manganese complexes and their use as catalysts - Google Patents
Bioconjugates of manganese complexes and their use as catalystsInfo
- Publication number
- NO980649L NO980649L NO980649A NO980649A NO980649L NO 980649 L NO980649 L NO 980649L NO 980649 A NO980649 A NO 980649A NO 980649 A NO980649 A NO 980649A NO 980649 L NO980649 L NO 980649L
- Authority
- NO
- Norway
- Prior art keywords
- bioconjugates
- catalysts
- manganese complexes
- mimicking
- sod
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Abstract
Biokonjugater av lavmolekylvekt etterligninger av superoksid dismutase (SOD) representert ved formel (I): hvori R, R1, R,, R1,, R2, R'2, R3, R'3, R,,, R'4) R5> R'5) R^, R'6, R7, R'7> R8, R'8> Rg, R'9, X, Y, Z og n er definert heri, er nyttige som terapeutiske midler for inflammatoriske sykdomstilstander og forstyrrelser, så som ischemi/reperfusjonsskade, slag, aterosklerose og alle andre tilstander med oksidant- indusert vevsskade eller andre skader.Low-molecular-weight bioconjugates mimicking superoxide dismutase (SOD) represented by formula (I): wherein R, R1, R ,, R1, R2, R'2, R3, R'3, R ,,, R'4) R5> R'5) R6, R'6, R7, R'7> R8, R'8> Rg, R'9, X, Y, Z and n are defined herein as useful as therapeutic agents for inflammatory disease states and disorders , such as ischemia / reperfusion injury, stroke, atherosclerosis and all other conditions with oxidant-induced tissue injury or other damage.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US242195P | 1995-08-17 | 1995-08-17 | |
PCT/US1996/012767 WO1997006824A2 (en) | 1995-08-17 | 1996-08-14 | Bioconjugates of manganese complexes and their application as catalysts |
Publications (2)
Publication Number | Publication Date |
---|---|
NO980649D0 NO980649D0 (en) | 1998-02-16 |
NO980649L true NO980649L (en) | 1998-04-02 |
Family
ID=21700675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO980649A NO980649L (en) | 1995-08-17 | 1998-02-16 | Bioconjugates of manganese complexes and their use as catalysts |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0844886A2 (en) |
JP (1) | JP2000513322A (en) |
KR (1) | KR19990037647A (en) |
CN (1) | CN1200039A (en) |
AU (1) | AU700958B2 (en) |
BR (1) | BR9610347A (en) |
CA (1) | CA2229799A1 (en) |
CZ (1) | CZ39898A3 (en) |
IL (1) | IL123040A0 (en) |
NO (1) | NO980649L (en) |
PL (1) | PL324993A1 (en) |
WO (1) | WO1997006824A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2254142T3 (en) | 1999-01-25 | 2006-06-16 | National Jewish Medical And Research Center | REPLACED PORPHIRINS AND THEIR THERAPEUTIC USE. |
US6749832B2 (en) | 1999-12-23 | 2004-06-15 | Amersham Plc | Labelled ascorbic acid derivatives |
US20050176790A1 (en) | 2001-02-28 | 2005-08-11 | Johannes Bartholomaus | Pharmaceutical salts |
EP1439842A4 (en) | 2001-06-01 | 2009-09-02 | Nat Jewish Med & Res Center | Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance |
KR20140001257A (en) | 2008-05-13 | 2014-01-06 | 유니버시티 오브 캔사스 | Metal abstraction peptide(map) tag and associated methods |
RU2506083C2 (en) | 2008-05-23 | 2014-02-10 | Нэшнл Джуиш Хелт | Method of treating disorders associated with alkylating agent exposure |
CN103906756B (en) * | 2011-09-26 | 2020-03-03 | 加莱拉实验室有限责任公司 | Methods for treating diseases |
WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
AU2018221043A1 (en) * | 2017-02-15 | 2019-09-12 | Galera Labs, Llc | Pentaaza macrocyclic ring complexes for local intestinal delivery |
CN108752383B (en) * | 2018-05-02 | 2020-10-30 | 江苏理工学院 | Pyrazole carboxylate manganese complex with SOD activity and preparation method thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0281463A3 (en) * | 1987-03-06 | 1989-01-25 | Sumitomo Pharmaceuticals Company, Limited | Platinum complex, process for its preparation and pharmaceutical composition including such a complex |
ATE164164T1 (en) * | 1991-07-19 | 1998-04-15 | Monsanto Co | MANGANEOUS COMPLEXES WITH NITROGEN-CONTAINING MACROCYCLIC LIGANDS, ACTIVE AS SUPEROXIDE DISMUTASE CATALYSTS. |
US6204259B1 (en) * | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
CN1152880A (en) * | 1994-04-22 | 1997-06-25 | 孟山都公司 | Diagnostic image analysis with metal complexes |
US6525041B1 (en) * | 1995-06-06 | 2003-02-25 | Pharmacia Corporation | Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
AU5928396A (en) * | 1995-06-07 | 1996-12-30 | Monsanto Company | Process for preparing substituted polyazamacrocycles |
-
1996
- 1996-08-14 CZ CZ98398A patent/CZ39898A3/en unknown
- 1996-08-14 CA CA002229799A patent/CA2229799A1/en not_active Abandoned
- 1996-08-14 EP EP96928057A patent/EP0844886A2/en not_active Withdrawn
- 1996-08-14 IL IL12304096A patent/IL123040A0/en unknown
- 1996-08-14 KR KR1019980701124A patent/KR19990037647A/en not_active Application Discontinuation
- 1996-08-14 PL PL96324993A patent/PL324993A1/en unknown
- 1996-08-14 CN CN96197626A patent/CN1200039A/en active Pending
- 1996-08-14 JP JP09509336A patent/JP2000513322A/en active Pending
- 1996-08-14 AU AU67655/96A patent/AU700958B2/en not_active Ceased
- 1996-08-14 BR BR9610347A patent/BR9610347A/en not_active Application Discontinuation
- 1996-08-14 WO PCT/US1996/012767 patent/WO1997006824A2/en not_active Application Discontinuation
-
1998
- 1998-02-16 NO NO980649A patent/NO980649L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1997006824A2 (en) | 1997-02-27 |
EP0844886A2 (en) | 1998-06-03 |
IL123040A0 (en) | 1998-09-24 |
CA2229799A1 (en) | 1997-02-27 |
AU700958B2 (en) | 1999-01-14 |
MX9801322A (en) | 1998-05-31 |
JP2000513322A (en) | 2000-10-10 |
BR9610347A (en) | 1999-06-01 |
AU6765596A (en) | 1997-03-12 |
NO980649D0 (en) | 1998-02-16 |
WO1997006824A3 (en) | 1997-07-03 |
CN1200039A (en) | 1998-11-25 |
CZ39898A3 (en) | 1998-07-15 |
PL324993A1 (en) | 1998-07-06 |
KR19990037647A (en) | 1999-05-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |