NO980275L - Double virus inactivated human blood plasma, blood plasma derivatives prepared therefrom and method for their preparation - Google Patents

Double virus inactivated human blood plasma, blood plasma derivatives prepared therefrom and method for their preparation

Info

Publication number
NO980275L
NO980275L NO980275A NO980275A NO980275L NO 980275 L NO980275 L NO 980275L NO 980275 A NO980275 A NO 980275A NO 980275 A NO980275 A NO 980275A NO 980275 L NO980275 L NO 980275L
Authority
NO
Norway
Prior art keywords
blood plasma
preparation
prepared therefrom
derivatives prepared
inactivated human
Prior art date
Application number
NO980275A
Other languages
Norwegian (no)
Other versions
NO311662B1 (en
NO980275D0 (en
Inventor
Annick Faucompre
Guenter Woeber
Original Assignee
Blotspendedienst Der Drk Lande
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blotspendedienst Der Drk Lande filed Critical Blotspendedienst Der Drk Lande
Publication of NO980275L publication Critical patent/NO980275L/en
Publication of NO980275D0 publication Critical patent/NO980275D0/en
Publication of NO311662B1 publication Critical patent/NO311662B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention concerns a method of producing a virally safe therapeutic biological preparation from human plasma using a detergent and retaining at least 50 % of the biological activity, the detergent being removed at the end of the method. Non-ionic surfactants, whose molecular structure comprises a hydrophobic part consisting of a linear aliphatic chain of between 8 and 10 carbon atoms, are used as detergents. The detergent treatment can be followed by a heat treatment, optionally using conventional stabilizers.
NO19980275A 1995-08-01 1998-01-21 Process for Preparing a Virus-Safe, Therapeutic Biological Preparation from Human Plasma Using Nonionic Surfactants NO311662B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19528221A DE19528221C2 (en) 1995-08-01 1995-08-01 Process for the production of a virus-safe, therapeutic preparation from human plasma
PCT/EP1995/004309 WO1997004815A1 (en) 1995-08-01 1995-11-03 Doubly virus-inactivated human blood plasma, blood plasma derivatives produced therefrom and method for their production

Publications (3)

Publication Number Publication Date
NO980275L true NO980275L (en) 1998-01-21
NO980275D0 NO980275D0 (en) 1998-01-21
NO311662B1 NO311662B1 (en) 2002-01-02

Family

ID=7768410

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19980275A NO311662B1 (en) 1995-08-01 1998-01-21 Process for Preparing a Virus-Safe, Therapeutic Biological Preparation from Human Plasma Using Nonionic Surfactants

Country Status (10)

Country Link
EP (1) EP0841954B1 (en)
AT (1) ATE183928T1 (en)
AU (1) AU3846595A (en)
CA (1) CA2228031A1 (en)
DE (2) DE19528221C2 (en)
DK (1) DK0841954T3 (en)
ES (1) ES2137544T3 (en)
GR (1) GR3031779T3 (en)
NO (1) NO311662B1 (en)
WO (1) WO1997004815A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
AU2018331357A1 (en) 2017-09-18 2020-04-02 Bayer Healthcare Llc Methods of inactivation of viruses using N-methylglucamides and its Derivatives
KR20200100771A (en) 2017-12-19 2020-08-26 체에스엘 베링 렝나우 아게 Protein purification and virus inactivation by alkyl glycosides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3173208D1 (en) * 1980-10-06 1986-01-23 Edward Shanbrom Method of reducing undesirable activities of biological and pharmaceutical products
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
FR2674536B1 (en) * 1991-03-29 1994-10-21 Fondation Nale Transfusion San VIRUS INACTIVATION PROCESS AND PHARMACEUTICAL COMPOSITION FOR VIRUS INACTIVATION.
AU6653094A (en) * 1992-12-16 1994-07-04 Immuno Aktiengesellschaft Process for preparing a virus-safe biological composition
DE4318435C2 (en) * 1993-02-09 1997-01-23 Octapharma Ag Method for inactivating viruses that are not provided with lipid envelopes

Also Published As

Publication number Publication date
DE19528221C2 (en) 1998-10-22
GR3031779T3 (en) 2000-02-29
CA2228031A1 (en) 1997-02-13
ATE183928T1 (en) 1999-09-15
NO311662B1 (en) 2002-01-02
AU3846595A (en) 1997-02-26
EP0841954B1 (en) 1999-09-01
DK0841954T3 (en) 2000-03-27
DE19528221A1 (en) 1997-02-06
WO1997004815A1 (en) 1997-02-13
NO980275D0 (en) 1998-01-21
ES2137544T3 (en) 1999-12-16
DE59506747D1 (en) 1999-10-07
EP0841954A1 (en) 1998-05-20

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN MAY 2003