NO962535L - Di-tert-butylphenol compounds useful as anti-inflammatory agents - Google Patents
Di-tert-butylphenol compounds useful as anti-inflammatory agentsInfo
- Publication number
- NO962535L NO962535L NO962535A NO962535A NO962535L NO 962535 L NO962535 L NO 962535L NO 962535 A NO962535 A NO 962535A NO 962535 A NO962535 A NO 962535A NO 962535 L NO962535 L NO 962535L
- Authority
- NO
- Norway
- Prior art keywords
- tert
- inflammatory agents
- compounds useful
- butylphenol compounds
- integer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Oppfinnelsen vedrører preparater omfattende: (a) en sikker og effektiv mengde av en forbindelse med strukturformelen (i) hvor n er et helt tall fra l til omtrent 5, m er et helt tall fra O til omtrent 3, -R er hydrogen eller rettkjedet eller forgrenet Cj-C^-alkanyl, og (b) en farmasøytisk tålbar bærer. Oppfinnelsen vedrører også metoder for å behandle sykdommer som er kjennetegnet ved inflammasjon og/eller smerte, som reumatoid artritt og osteoartritt, ved å administrere en sikker og effektiv mengde av denne forbindelse til et menneske eller lavere dyr med behov for slik behandling.The invention relates to compositions comprising: (a) a safe and effective amount of a compound of structural formula (i) wherein n is an integer from 1 to about 5, m is an integer from 0 to about 3, -R is hydrogen or straight chain or branched Cj-C ^ alkanyl, and (b) a pharmaceutically tolerable carrier. The invention also relates to methods of treating diseases characterized by inflammation and / or pain, such as rheumatoid arthritis and osteoarthritis, by administering a safe and effective amount of this compound to a human or lower animal in need of such treatment.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16934793A | 1993-12-17 | 1993-12-17 | |
| PCT/US1994/014405 WO1995016443A1 (en) | 1993-12-17 | 1994-12-16 | Di-tert-butylphenol compounds useful as anti-inflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO962535D0 NO962535D0 (en) | 1996-06-14 |
| NO962535L true NO962535L (en) | 1996-08-15 |
Family
ID=22615292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO962535A NO962535L (en) | 1993-12-17 | 1996-06-14 | Di-tert-butylphenol compounds useful as anti-inflammatory agents |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0734256A1 (en) |
| JP (1) | JPH09506624A (en) |
| CN (1) | CN1137752A (en) |
| AU (1) | AU702254B2 (en) |
| BR (1) | BR9408334A (en) |
| CA (1) | CA2179009A1 (en) |
| CZ (1) | CZ285436B6 (en) |
| HU (1) | HUT74507A (en) |
| NO (1) | NO962535L (en) |
| NZ (1) | NZ277986A (en) |
| PL (1) | PL315061A1 (en) |
| SK (1) | SK76996A3 (en) |
| WO (1) | WO1995016443A1 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4130666A (en) * | 1977-05-16 | 1978-12-19 | Riker Laboratories, Inc. | Anti-inflammatory method |
| US5280045A (en) * | 1991-10-16 | 1994-01-18 | The Procter & Gamble Company | 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent |
-
1994
- 1994-12-16 PL PL94315061A patent/PL315061A1/en unknown
- 1994-12-16 WO PCT/US1994/014405 patent/WO1995016443A1/en not_active Application Discontinuation
- 1994-12-16 CN CN94194537A patent/CN1137752A/en active Pending
- 1994-12-16 BR BR9408334A patent/BR9408334A/en not_active Application Discontinuation
- 1994-12-16 EP EP95904909A patent/EP0734256A1/en not_active Ceased
- 1994-12-16 CA CA002179009A patent/CA2179009A1/en not_active Abandoned
- 1994-12-16 AU AU13722/95A patent/AU702254B2/en not_active Ceased
- 1994-12-16 SK SK769-96A patent/SK76996A3/en unknown
- 1994-12-16 HU HU9601656A patent/HUT74507A/en unknown
- 1994-12-16 JP JP7516940A patent/JPH09506624A/en active Pending
- 1994-12-16 NZ NZ277986A patent/NZ277986A/en unknown
- 1994-12-16 CZ CZ961755A patent/CZ285436B6/en not_active IP Right Cessation
-
1996
- 1996-06-14 NO NO962535A patent/NO962535L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2179009A1 (en) | 1995-06-22 |
| EP0734256A1 (en) | 1996-10-02 |
| JPH09506624A (en) | 1997-06-30 |
| CN1137752A (en) | 1996-12-11 |
| BR9408334A (en) | 1997-08-19 |
| SK76996A3 (en) | 1997-05-07 |
| WO1995016443A1 (en) | 1995-06-22 |
| NZ277986A (en) | 1998-03-25 |
| HUT74507A (en) | 1997-01-28 |
| HU9601656D0 (en) | 1996-08-28 |
| CZ285436B6 (en) | 1999-08-11 |
| AU702254B2 (en) | 1999-02-18 |
| PL315061A1 (en) | 1996-09-30 |
| AU1372295A (en) | 1995-07-03 |
| NO962535D0 (en) | 1996-06-14 |
| CZ175596A3 (en) | 1996-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |