NO961539L - Et nytt prostata-/colontumorsuppressorgen lokalisert på humant kromosom 8 - Google Patents

Et nytt prostata-/colontumorsuppressorgen lokalisert på humant kromosom 8

Info

Publication number
NO961539L
NO961539L NO961539A NO961539A NO961539L NO 961539 L NO961539 L NO 961539L NO 961539 A NO961539 A NO 961539A NO 961539 A NO961539 A NO 961539A NO 961539 L NO961539 L NO 961539L
Authority
NO
Norway
Prior art keywords
tumor suppressor
colon tumor
suppressor gene
prostate
human chromosome
Prior art date
Application number
NO961539A
Other languages
English (en)
Other versions
NO961539D0 (no
Inventor
Robert Bookstein
William B Isaacs
Original Assignee
Canji Inc
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canji Inc, Univ Johns Hopkins filed Critical Canji Inc
Publication of NO961539L publication Critical patent/NO961539L/no
Publication of NO961539D0 publication Critical patent/NO961539D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår et nytt nukleinsyremolekyl kodende for et prostata/co- lontumorsuppressorgenprodukt. Midlene og fremgangsmåter for detektering av mutasjoner og/eller tap av prostata/colontumorsuppressorgen er fremskaffet. Også inkludert innen rammen av oppfinnelsen er fremgangsmåter for undertrykkelse av den neo- plastiske fenotype av cancerceller som har en defekt på prostata/colontumorsuppressor- genprodukt. Oppfinnelsen omfatter også midler og fremgangsmåter for behandling av cancer ved administrering av prostata/colon-rumorsuppressorgenet.
NO961539A 1994-05-20 1996-04-18 Et nytt prostata-/colontumorsuppressorgen lokalisert på humant kromosom 8 NO961539D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24660494A 1994-05-20 1994-05-20
PCT/US1995/006593 WO1995032214A1 (en) 1994-05-20 1995-05-22 A novel prostate/colon tumor suppressor gene located on human chromosome 8

Publications (2)

Publication Number Publication Date
NO961539L true NO961539L (no) 1996-04-18
NO961539D0 NO961539D0 (no) 1996-04-18

Family

ID=22931368

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961539A NO961539D0 (no) 1994-05-20 1996-04-18 Et nytt prostata-/colontumorsuppressorgen lokalisert på humant kromosom 8

Country Status (8)

Country Link
EP (1) EP0714401A4 (no)
AU (1) AU686815B2 (no)
CA (1) CA2170627A1 (no)
CZ (1) CZ53196A3 (no)
FI (1) FI961723A (no)
NO (1) NO961539D0 (no)
SK (1) SK24696A3 (no)
WO (1) WO1995032214A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7384735B1 (en) 1986-08-11 2008-06-10 Massachusetts Eye And Ear Infirmary Retinoblastoma nucleic acids
US7223842B1 (en) 1986-08-11 2007-05-29 Massachusetts Eye And Ear Infirmary Detection of proteins whose absence is associated with a neoplasm
JP2000500329A (ja) * 1995-10-23 2000-01-18 インペリアル キャンサー リサーチ テクノロジィ リミテッド 癌罹病性の診断およびその治療
US6287854B1 (en) * 1996-10-22 2001-09-11 Imperial Cancer Research Technology Limited Diagnosis of susceptibility to cancer and treatment thereof
WO1999000498A1 (en) * 1997-06-27 1999-01-07 Human Genome Sciences, Inc. Human nk-3 related prostate specific gene-1
GB9903841D0 (en) 1999-02-20 1999-04-14 Imp College Innovations Ltd Diagnosis and treatment of cancer
JP2005522519A (ja) * 2002-04-05 2005-07-28 ユニヴァーシティ コート オブ ザ ユニヴァーシティ オブ エディンバラ 精神分裂病関連遺伝子
US6747555B2 (en) 2002-09-24 2004-06-08 International Business Machines Corporation Tracking apparatus and associated method for a radio frequency enabled reminder system

Also Published As

Publication number Publication date
CA2170627A1 (en) 1995-11-30
EP0714401A4 (en) 1999-03-03
WO1995032214A1 (en) 1995-11-30
SK24696A3 (en) 1997-02-05
AU2603495A (en) 1995-12-18
FI961723A0 (fi) 1996-04-19
EP0714401A1 (en) 1996-06-05
CZ53196A3 (en) 1997-05-14
NO961539D0 (no) 1996-04-18
FI961723A (fi) 1996-04-19
AU686815B2 (en) 1998-02-12

Similar Documents

Publication Publication Date Title
Radisky et al. Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?
FI961976A0 (fi) Peptidyyliyhdisteitä ja niiden terapeuttinen käyttö metalloproteinaasien inhibiittoreina
Whitcombe et al. Assignment of the human ferrochelatase gene (FECH) and a locus for protoporphyria to chromosome 18q22
Deguen et al. Heterogeneity of mesothelioma cell lines as defined by altered genomic structure and expression of the NF2 gene
Nataraj et al. Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers.
ATE295889T1 (de) Gentranskription und ionisierende strahlung: methoden und zusammensetzungen
MX9804009A (es) Inhibicion de crecimiento tumoral por oligonucleotidos de antisentido para il-8 y receptor de il-8.
FI970513A (fi) In vivo mutaatiot ja polymorfismit 17q:hun liittyvässä rinta- ja munasarjasyöpäalttiusgeenissä
Berggren et al. p53 mutations in urinary bladder cancer
NO961539L (no) Et nytt prostata-/colontumorsuppressorgen lokalisert på humant kromosom 8
Del Baldo et al. Rhabdoid tumor predisposition syndrome: from clinical suspicion to general management
Busam et al. Reduced H3K27me3 expression in Merkel cell polyoma virus-positive tumors
Tsao et al. Further evidence that one of the earliest alterations in colorectal carcinogenesis involves APC.
DE69635207D1 (de) Auf Chromosom 1 lokalisiertes Gen dessen Genprodukt mit der Alzheimerschen Krankheit assoziiert ist.
ATE299854T1 (de) Chinonverbindungen zur behandlung von krankheiten
Parshad et al. Radiation-induced chromatid breaks and deficient DNA repair in cancer predisposition
Islam et al. Promoter hypermethylation inactivate tumor suppressor FAM134B and is associated with poor prognosis in colorectal cancer
AR011607A1 (es) Polipeptido aislado que codifica un supresor tumoral ts10q23.3, anticuerpo monoclonal , celula de hibridoma, antisuero policlonal, acido nucleico yoligonucleotido aislados. metodo para diagnosticar cancer, alterar el fenotipo de una celula tumoral, determinar el estadio de un cancer, pronosticar
ATE309812T1 (de) Verwendung von adenoviren mit mutationen in den va-genen für die krebstherapie
WO2004063356A3 (en) Persistent expression of candidate molecule in proliferating stem and progenitor cells for delivery of therapeutic products
ATE298003T1 (de) Ein tumorsuppressor namens ts10q23.3
TNSN97033A1 (fr) Nouvelles heteroaryl-oxazolidinones, procede pour les preparer, et leur utilisation en tant que medicaments.
Tacar et al. Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer
Park The Role of Epigenetics in Brain and Spinal Cord Tumors
NO961221D0 (no) Fremgangsmåte til å identifisere nye gener assosiert med setepreferert cancer mestastasedannelse