NO952465L - Process for Preparation of Aryl-Condensed and Heteraryl-Condensed-2,4-Diazepine and 2,4-Diazocin Compounds - Google Patents
Process for Preparation of Aryl-Condensed and Heteraryl-Condensed-2,4-Diazepine and 2,4-Diazocin CompoundsInfo
- Publication number
- NO952465L NO952465L NO952465A NO952465A NO952465L NO 952465 L NO952465 L NO 952465L NO 952465 A NO952465 A NO 952465A NO 952465 A NO952465 A NO 952465A NO 952465 L NO952465 L NO 952465L
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- phenyl
- benzyl
- halogen
- lower alkoxy
- Prior art date
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Aryl-kondensert- og hetaryH{andensert-2,4-diazeplner og -dlazoclner av de generelle formler: R» .-«*¿ R" R»' eller (XXXa) samt aryldlretanardner av formler: (Ha) (Via) (VTb) (IVa) hvor R1 er hydrogen, laverealkyl, benzyl, naftyl, tlenyl, pyridlnyl, fenyl, eller fenyl son har en eller to substltuenter valgt fra laverealkyl og lavere- alkoksy; R2 er hydrogen; laverealkyl; benzyl; fenyl; fenyl substituert med halogen, laverealkyl eller laverealkoksy; eller R2 er -OtøCHgR7, hvor R7 er laverealkoksy, benzyl, dl-( laverealkyl )amlno, pyrrolidlno, piperldlno, morfollno, fenyl, eller fenyl substituert med amlno, nltro eller lavereallqrlsulfonanido: R2" er hydrogen; lavereallgrl; dl(laverealKyl)aminoalXyl: benzyl; fenyl; fenetyl eller fenyl substituert med halogen, laverealkyl eller laverealkoksy; R33 er (YaL-(CH2)m-(Xa)n-R8, hvor Ya, p. m, n & og R8 har forskjellige betydninger; R5er hydrogen; laverealkyl; naftyl; tienyl; pyridinyl; benzyl; fenyl; eller fenyl son har en eller to substituanter valgt fra laverealkyl, laverealkoksy, halogen, hydroksyl, amlno, dl(laverealkyl )amino, laverealkylsulfmamido og lavereacylamlno; R¿ er hydrogen; laverealkyl: naftyl; tienyl; pyrldlnyl; benzyl; fenyl; eller fenyl som har en eller to substituenter valgt fra laverealtyl, laverealkcksy og halogen; R50 er laverealkyl: fenyl; naftyl; tienyl; pyrldlnyl: benzyl: eller fenyl son har en eller to substltuenter valgt fra laverealkyl, laverealkoksy og halogen; R6 er en eller to substituenter valgt uavhengig fra gruppen bestående av hydrogen, laverealkyl, laverealkoksy, halogen; nltro og laverealkylsulfonamido eller R° er en kondensert benzenrlng; R^ er en eller to substltuenter valgt uavhengig fra gruppen bestående av hydrogen, laverealkyl, laverealkcksy og halogen. Det er videre beskrevet frerrgangsnåter for fremstilling av de ovenfor angitte forbindelsene son har nyttevirkning ved behandling av hjertearytmi.Aryl-condensed and hetaryl {other-2,4-diazeplanes and dlazoclns of the general formulas: R R.. «*R ellerR eller or (XXXa) as well as aryltrethane ordinates of formulas: (Ha) (Via) ( VTb) (IVa) wherein R 1 is hydrogen, lower alkyl, benzyl, naphthyl, tlenyl, pyridinyl, phenyl, or phenyl son has one or two substituents selected from lower alkyl and lower alkoxy; R2 is hydrogen; lower alkyl; benzyl; phenyl; or halo, lower alkyl or lower alkoxy; or R 2 is -OtochCHR R 7, wherein R 7 is lower alkoxy, benzyl, dl- (lower alkyl) amino, pyrrolidino, piperidino, morpholno, phenyl, or phenyl substituted with amino, nitro or lower alkoxy; lavereallgrl; dl (lower alkyl) aminoalXyl: benzyl; phenyl; phenethyl or phenyl substituted with halogen, lower alkyl or lower alkoxy; R33 is (YaL- (CH2) m- (Xa) n-R8, where Ya, p. M, n & and R8 have different meanings; R5 is hydrogen; loweralkyl; naphthyl; thienyl; pyridinyl; benzyl; phenyl; or phenyl zone has one or two substituents selected from lower alkyl, lower alkoxy, halogen, hydroxyl, amino, dl (lower alkyl) amino, lower alkyl sulfamamido and lower acylamino; R 8 is hydrogen; lower alkyl: naphthyl; thienyl; pyridylnyl; benzyl or phenyl; two substituents selected from lower alkyl, lower alkoxy and halogen; R 50 is lower alkyl: phenyl; naphthyl; thienyl; pyridinyl: benzyl: or phenyl son has one or two substituents selected from lower alkyl, lower alkoxy and halogen; R 6 is one or two substituents selected independently of the group consisting of hydrogen, lower alkyl, lower alkoxy, halogen; nitro and lower alkyl sulfonamido or R ° is a fused benzene ring; R 2 is one or two substituents independently selected from the group consisting of hydrogen, lower alkyl, lower alkoxy and halogen. Benefits for preparing the above compounds are useful in treating cardiac arrhythmias.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO952465A NO952465L (en) | 1990-09-10 | 1995-06-20 | Process for Preparation of Aryl-Condensed and Heteraryl-Condensed-2,4-Diazepine and 2,4-Diazocin Compounds |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58006590A | 1990-09-10 | 1990-09-10 | |
US74385391A | 1991-06-13 | 1991-06-13 | |
NO913566A NO300268B1 (en) | 1990-09-10 | 1991-09-10 | Analogous Process for Preparation of Therapeutically Active Aryl Condensed and Hetaryl Condensed 2,4-Diazepine Compounds |
NO952465A NO952465L (en) | 1990-09-10 | 1995-06-20 | Process for Preparation of Aryl-Condensed and Heteraryl-Condensed-2,4-Diazepine and 2,4-Diazocin Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
NO952465D0 NO952465D0 (en) | 1995-06-20 |
NO952465L true NO952465L (en) | 1995-06-20 |
Family
ID=27484208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO952465A NO952465L (en) | 1990-09-10 | 1995-06-20 | Process for Preparation of Aryl-Condensed and Heteraryl-Condensed-2,4-Diazepine and 2,4-Diazocin Compounds |
Country Status (1)
Country | Link |
---|---|
NO (1) | NO952465L (en) |
-
1995
- 1995-06-20 NO NO952465A patent/NO952465L/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO952465D0 (en) | 1995-06-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0111596A (en) | Compound and its use, process for its production, pharmaceutical composition and process and method for preventing or treating disease | |
FR2755967B1 (en) | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS | |
NO900336L (en) | PROCEDURE FOR THE PREPARATION OF HETEROCYCLIC COMPOUNDS. | |
ES8301201A1 (en) | Nitro-derivatives of the benzene series and their use in the dyeing of keratin fibres | |
NO955326L (en) | Isoquinoline derivatives, process for their preparation and therapeutic use | |
FR2696344B1 (en) | Use in dyeing keratin fibers of sulfur metaphenylenediamines and new sulfur metaphenylenediamines. | |
NO305287B1 (en) | AMPA antagonists | |
ES8300745A1 (en) | 2-(4-Piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines. | |
MY100115A (en) | Nitrogen containing heterocyclic compounds, and their production and use. | |
DK452687A (en) | DIHYDROPYRIDINE COMPOUNDS, ISOMERS, ISOMER MIXTURES, OPTICAL ANTIPODES AND RACEMATES THEREOF, THEIR PREPARATION AND USE AS MEDICINES | |
CA2179306A1 (en) | Dopamine receptor ligands | |
NO952465L (en) | Process for Preparation of Aryl-Condensed and Heteraryl-Condensed-2,4-Diazepine and 2,4-Diazocin Compounds | |
RO80087B (en) | Process for preparing thiazolylidene-oxo-p opionitriles | |
IE830976L (en) | 3-(arylthiomethyl)pyridines. | |
ATE69220T1 (en) | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTEN,N'-DIACYLHYDRAZINES. | |
ZA849047B (en) | Aralykyl(arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives | |
DE3666432D1 (en) | Aromatic compounds, their preparation and use | |
ATE25083T1 (en) | AMINOPROPANOL DERIVATIVES OF SUBSTITUTED 2HYDROXY-PROPIOPHENONES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM. | |
NO990285D0 (en) | Thienylcyclohexane derivatives for thienylcyclohexyl synthesis | |
NZ335975A (en) | Heterocyclic substituted pyrrolidine amide derivatives useful in treating respiratory diseases | |
NO981000L (en) | 4- (cycloalkyl) piperidine and 4- (cycloalkylalkyl) piperidine derivatives, their preparation and therapeutic use | |
HUP0001118A2 (en) | N-substituted pyrrolidine derivatives, process for preparing the same and pharmaceutical compositions containing them | |
PT755393E (en) | NEW CRYSTALLINE FORMS OF 1-η5-METHANOSULFONAMIDEIMDOLYL-2-CARBONYL-4- [3- (1-METHYLETHYLAMINO) -2-PYRIDINYL PIPERAZINE | |
FR2456102B1 (en) | ||
FR2446824A1 (en) | 4,5,6,7-TETRAHYDRO-1H (OR 2H) -INDAZOLES WITH AMINO GROUP AND THEIR THERAPEUTIC USE |