NO951812L - Pyrrole derivatives, their preparation and use - Google Patents
Pyrrole derivatives, their preparation and useInfo
- Publication number
- NO951812L NO951812L NO951812A NO951812A NO951812L NO 951812 L NO951812 L NO 951812L NO 951812 A NO951812 A NO 951812A NO 951812 A NO951812 A NO 951812A NO 951812 L NO951812 L NO 951812L
- Authority
- NO
- Norway
- Prior art keywords
- group
- branched
- alkyl
- pyrrole derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
5,6-dihydro-4H-tieno[3,4-c]pyrrolderivater med generell formel (D £OY> yT H N---' (I) hvor R! enten representerer en cyanogruppe, C}_4 alkoksy, C^ alkyltio, C:_t alkylsulfonyl, pyridyl, 3,4-dimetoksyfenyl eller cyklopropyl som eventuelt er substituert med en eller to alkylgrupper, eller en gruppe COR hvor R er en C^.^ alkyl- gruppe, fenyl eller piperidinyl, eller en benzylgruppe som er substituert med et eller flere halogenatomer og/eller rett- kjedet eller forgrenet C^ alkyl, rettkjedet eller forgrenet C^ alkoksy eller C02R' hvor R' er en rettkjedet eller forgrenet C1.4 alkylgruppe, eller en naftylmetylgruppe, og deres addisjonssalter med farmasøytisk tålbare syrer. Derivatene har terapeutisk anvendelse.5,6-dihydro-4H-thieno [3,4-c] pyrrole derivatives of general formula (D5 OY> yT H N --- '(I) where R 1 represents either a cyano group, C alkylthio, C1-6 alkylsulfonyl, pyridyl, 3,4-dimethoxyphenyl or cyclopropyl optionally substituted with one or two alkyl groups, or a group COR where R is a C1-4 alkyl group, phenyl or piperidinyl, or a benzyl group which are substituted by one or more halogen atoms and / or straight or branched C1-4 alkyl, straight chain or branched C1-4 alkoxy or CO2R 'wherein R' is a straight chain or branched C1-4 alkyl group, or a naphthylmethyl group, and their addition salts with pharmaceutical The derivatives have therapeutic use.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9405716A FR2719844B1 (en) | 1994-05-10 | 1994-05-10 | 5,6-dihydro-4h-thieno [3,4-c] pyrrole derivatives, their preparation and their therapeutic use. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO951812D0 NO951812D0 (en) | 1995-05-09 |
| NO951812L true NO951812L (en) | 1995-11-13 |
Family
ID=9463059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO951812A NO951812L (en) | 1994-05-10 | 1995-05-09 | Pyrrole derivatives, their preparation and use |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0682028A1 (en) |
| JP (1) | JPH0853457A (en) |
| KR (1) | KR950032205A (en) |
| CN (1) | CN1117970A (en) |
| AU (1) | AU1793395A (en) |
| CA (1) | CA2148880A1 (en) |
| CZ (1) | CZ119695A3 (en) |
| FI (1) | FI952250A (en) |
| FR (1) | FR2719844B1 (en) |
| HU (1) | HUT72667A (en) |
| IL (1) | IL113673A0 (en) |
| NO (1) | NO951812L (en) |
| NZ (1) | NZ272090A (en) |
| PL (1) | PL308516A1 (en) |
| RU (1) | RU95107154A (en) |
| SK (1) | SK59795A3 (en) |
| ZA (1) | ZA953749B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19514579A1 (en) | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Use of alpha-1-olone agonists for the treatment of urinary incontinence |
| FR2733750B1 (en) * | 1995-05-03 | 1997-06-13 | Synthelabo | DERIVATIVES OF GAMMA-OXO-ALPHA- (PHENYLMETHYL) -5,6- DIHYDRO-4H-THIENO (3,4-C) PYRROLE-5-BUTANOIQUE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
| CA2327543A1 (en) | 1998-05-06 | 1999-11-11 | Duke University | Method of treating bladder and lower urinary tract syndromes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8529546D0 (en) * | 1985-11-30 | 1986-01-08 | Beecham Group Plc | Compounds |
| AU664710B2 (en) * | 1991-08-27 | 1995-11-30 | Upjohn Company, The | A method for treatment of metabolic disorders |
| EP0599697A1 (en) * | 1992-11-24 | 1994-06-01 | Synthelabo | Pyrrole derivatives, their preparation and application in therapy |
-
1994
- 1994-05-10 FR FR9405716A patent/FR2719844B1/en not_active Expired - Fee Related
-
1995
- 1995-05-03 EP EP95401015A patent/EP0682028A1/en not_active Withdrawn
- 1995-05-08 CA CA002148880A patent/CA2148880A1/en not_active Abandoned
- 1995-05-09 NZ NZ272090A patent/NZ272090A/en unknown
- 1995-05-09 HU HU9501370A patent/HUT72667A/en unknown
- 1995-05-09 IL IL11367395A patent/IL113673A0/en unknown
- 1995-05-09 JP JP7110539A patent/JPH0853457A/en active Pending
- 1995-05-09 SK SK597-95A patent/SK59795A3/en unknown
- 1995-05-09 PL PL95308516A patent/PL308516A1/en unknown
- 1995-05-09 KR KR1019950011238A patent/KR950032205A/en not_active Application Discontinuation
- 1995-05-09 ZA ZA953749A patent/ZA953749B/en unknown
- 1995-05-09 AU AU17933/95A patent/AU1793395A/en not_active Abandoned
- 1995-05-09 CN CN95105472A patent/CN1117970A/en active Pending
- 1995-05-09 NO NO951812A patent/NO951812L/en unknown
- 1995-05-09 FI FI952250A patent/FI952250A/en unknown
- 1995-05-09 CZ CZ951196A patent/CZ119695A3/en unknown
- 1995-05-15 RU RU95107154/04A patent/RU95107154A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ272090A (en) | 1996-03-26 |
| RU95107154A (en) | 1997-03-20 |
| FI952250A (en) | 1995-11-11 |
| FI952250A0 (en) | 1995-05-09 |
| SK59795A3 (en) | 1995-12-06 |
| NO951812D0 (en) | 1995-05-09 |
| EP0682028A1 (en) | 1995-11-15 |
| CZ119695A3 (en) | 1995-11-15 |
| HUT72667A (en) | 1996-05-28 |
| JPH0853457A (en) | 1996-02-27 |
| ZA953749B (en) | 1996-04-02 |
| CN1117970A (en) | 1996-03-06 |
| IL113673A0 (en) | 1995-08-31 |
| CA2148880A1 (en) | 1995-11-11 |
| PL308516A1 (en) | 1995-11-13 |
| AU1793395A (en) | 1995-11-16 |
| KR950032205A (en) | 1995-12-20 |
| FR2719844B1 (en) | 1996-06-07 |
| FR2719844A1 (en) | 1995-11-17 |
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