NO951265L - Pharmaceutical preparations containing nonionic surfactants - Google Patents

Pharmaceutical preparations containing nonionic surfactants

Info

Publication number
NO951265L
NO951265L NO951265A NO951265A NO951265L NO 951265 L NO951265 L NO 951265L NO 951265 A NO951265 A NO 951265A NO 951265 A NO951265 A NO 951265A NO 951265 L NO951265 L NO 951265L
Authority
NO
Norway
Prior art keywords
nonionic surfactants
pharmaceutical preparations
preparations containing
active ingredient
containing nonionic
Prior art date
Application number
NO951265A
Other languages
Norwegian (no)
Other versions
NO951265D0 (en
Inventor
William John Curatolo
Michael J Gumkowski
Julian B Lo
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1993/008107 external-priority patent/WO1994007472A1/en
Application filed by Pfizer filed Critical Pfizer
Publication of NO951265D0 publication Critical patent/NO951265D0/en
Publication of NO951265L publication Critical patent/NO951265L/en

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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det beskrives farmasøytiske preparater som omfatter et enzymatisk labilt farmasøytisk virkestoff, som er permeabelt gjennom tarmveggen eller fordrer en intestinal permeabilitets- fremmer for å trenge gjennom tarmveggen, og minst ett ikke- ionisk overflateaktivt middel som er i stand til å beskytte det nevnte virkestoff mot deaktivering med enzymer. En fremgangsmåte for inhibering av nedbrytningen av et enzymatisk labilt farmasøytisk virkestoff gjennom gastro- intestinale enzymer, og som omfatter at det nevnte middel kombineres med et ikke-ionisk overflateaktivt middel, er også beskrevet.Pharmaceutical compositions are disclosed which comprise an enzymatic labile pharmaceutical active ingredient permeable through the intestinal wall or requiring an intestinal permeability promoter to penetrate the intestinal wall, and at least one nonionic surfactant capable of protecting said active ingredient from deactivation. with enzymes. A method of inhibiting the degradation of an enzymatic labile pharmaceutical active ingredient through gastrointestinal enzymes, comprising combining said agent with a nonionic surfactant, is also disclosed.

NO951265A 1992-10-02 1995-03-31 Pharmaceutical preparations containing nonionic surfactants NO951265L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95596292A 1992-10-02 1992-10-02
PCT/US1993/008107 WO1994007472A1 (en) 1992-10-02 1993-09-02 Pharmaceutical compositions containing nonionic surfactants

Publications (2)

Publication Number Publication Date
NO951265D0 NO951265D0 (en) 1995-03-31
NO951265L true NO951265L (en) 1995-05-31

Family

ID=26786990

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951265A NO951265L (en) 1992-10-02 1995-03-31 Pharmaceutical preparations containing nonionic surfactants

Country Status (1)

Country Link
NO (1) NO951265L (en)

Also Published As

Publication number Publication date
NO951265D0 (en) 1995-03-31

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