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Priority claimed from US07/886,984external-prioritypatent/US5276159A/en
Priority claimed from US07/939,104external-prioritypatent/US5281710A/en
Application filed by Scripps Research InstfiledCriticalScripps Research Inst
Publication of NO944429D0publicationCriticalpatent/NO944429D0/en
Publication of NO944429LpublicationCriticalpatent/NO944429L/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Saccharide Compounds
(AREA)
Abstract
En enantiomer av en fusjonert ringsystemforbindelse inneholdende en epoksidgruppe på en side av de fusjon- erte ringer og en endiyn-makrosyklisk ring på den andre side av de fusjonerte ringer. De enantiomere forbindelser har forhøyede DNA-spaltende, antimikro- bielle og tumorvekstinhiberende egen- skaper i forhold til deres racemater. Kimære forbindelser hvor den enantio- mere, fusjonerte ringsystemforbindelse foreligger som et aglykon bundet til (i) en sukkergruppe som oligosakkarid- del eller (ii) et monoklonalt antistoff eller en antistoffbindingssetedel derav som immunreagerer med tumormålceller, er også beskrevet. Preparater innehol- dende en enantiomer forbindelse eller en enantiomer kimær og fremgangsmåter for fremstilling av en enantiomer for- bindelse, er også beskrevet.An enantiomer of a fused ring system compound containing an epoxide group on one side of the fused rings and an endyynocyclic ring on the other side of the fused rings. The enantiomeric compounds have elevated DNA cleavage, antimicrobial and tumor growth inhibitory properties in relation to their racemates. Chimeric compounds in which the enantiomerized ring system compound is present as an aglycone bound to (i) a sugar moiety as an oligosaccharide moiety or (ii) a monoclonal antibody or antibody binding site thereof that immunoreact with tumor target cells are also described. Compositions containing an enantiomeric compound or an enantiomeric chimera and methods for preparing an enantiomeric compound are also described.
NO944429A1992-05-211994-11-18
Enantiomeric dynemicin analogs, method of preparation and use thereof
NO944429L
(en)
HERBICIDE COMPOUND, HERBICIDE COMPOSITION, PROCESS TO SERIOUSLY DAMAGE OR KILL UNWANTED PLANTS, PROCESS TO SELECTIVELY CONTROL THE GROWTH OF WEEDS AND PROCESS FOR THE SYNTHESIS OF A HERBICIDE COMPOUND
3-PHENOXYPYRAZOL OR AN AGRONOMICALLY ACCEPTABLE SALT OF THE SAME, HERBICIDE COMPOSITION, PROCESS TO CONTROL THE GROWTH OF UNWANTED PLANTS AND PROCESS FOR PREPARATION OF COMPOUNDS
COMPOSITION TO PROTECT CULTURE PLANTS, PHOSPHONATES, PHOSPHINATES, PHOSPHINOXIDES, PROCESS FOR THEIR PREPARATION, PROCESS FOR THE SELECTIVE COMBAT OF WEEDS, APPLICATION, PROCESS TO PROTECT CROP PLANTS AND SEED
MICROBICIDE COMPOSITION, PROCESS FOR PREPARATION OF COMPOUNDS PROCESS FOR PREPARATION OF SUCH COMPOSITION, AND PROCESS TO COMBAT OR AVOID AN INFESTATION OF CULTURE PLANTS BY PHYTOPATHOGENIC MICROORGANISMS