NO944208L - Novel quinazolines as inhibitors of HIV reverse transcriptase - Google Patents

Novel quinazolines as inhibitors of HIV reverse transcriptase

Info

Publication number
NO944208L
NO944208L NO944208A NO944208A NO944208L NO 944208 L NO944208 L NO 944208L NO 944208 A NO944208 A NO 944208A NO 944208 A NO944208 A NO 944208A NO 944208 L NO944208 L NO 944208L
Authority
NO
Norway
Prior art keywords
reverse transcriptase
inhibitors
hiv reverse
compounds
treating
Prior art date
Application number
NO944208A
Other languages
Norwegian (no)
Other versions
NO944208D0 (en
Inventor
Terry A Lyle
Thomas J Tucker
Catherine M Wiscount
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1993/003975 external-priority patent/WO1993022292A1/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO944208D0 publication Critical patent/NO944208D0/en
Publication of NO944208L publication Critical patent/NO944208L/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Forbindelser med en kina- zolin-2-on-kjerne med et substituert alkynyl eller substituert alkenyl ved 4-stillingen er beskrevet. Disse for- bindelser er anvendbare ved inhibering av HIV-reverstranskriptase (innbefatt- ende dens resistente varianter), for- hindring eller behandling av infeksjon av HIV og behandling av AIDS, enten som forbindelser, farmasøytisk akseptable salter, farmasøytiske preparatbestand- deler, enten eller ikke i kombinasjon med andre antivirale midler, immunmodu- latorer, antibiotika eller vaksiner. Metoder for behandling av AIDS og metoder for forhindring eller behandling av infeksjon av HIV er også beskrevet .Compounds with a quinazolin-2-one nucleus having a substituted alkynyl or substituted alkenyl at the 4-position are described. These compounds are useful in inhibiting HIV reverse transcriptase (including its resistant variants), preventing or treating HIV infection and treating AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical preparations, or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods for treating AIDS and methods for preventing or treating HIV infection are also described.

NO944208A 1992-05-07 1994-11-04 Novel quinazolines as inhibitors of HIV reverse transcriptase NO944208L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88011992A 1992-05-07 1992-05-07
US99116492A 1992-12-16 1992-12-16
PCT/US1993/003975 WO1993022292A1 (en) 1992-05-07 1993-04-28 New quinazolines as inhibitors of hiv reverse transcriptase

Publications (2)

Publication Number Publication Date
NO944208D0 NO944208D0 (en) 1994-11-04
NO944208L true NO944208L (en) 1995-01-06

Family

ID=27377375

Family Applications (1)

Application Number Title Priority Date Filing Date
NO944208A NO944208L (en) 1992-05-07 1994-11-04 Novel quinazolines as inhibitors of HIV reverse transcriptase

Country Status (1)

Country Link
NO (1) NO944208L (en)

Also Published As

Publication number Publication date
NO944208D0 (en) 1994-11-04

Similar Documents

Publication Publication Date Title
NO953308L (en) Inhibitors of HIV reverse transcriptase
NO954427L (en) HIV protease inhibitors useful for the treatment of AIDS
DK0582455T3 (en) Benzoxazinones as inhibitors of HIV reverse transcriptase
WO2003013484A3 (en) N-monoacylated derivatives of o-phenylenediamines, their six membered heterocyclic analogues and their use as pharmaceutical agents
ATE175412T1 (en) HIV PROTEASE INHIBITORS
NO922949L (en) RELATIONSHIPS AND PROCEDURES FOR INHIBITING HIV AND RELATED VIRUSES
NO962000L (en) Promoters of an HIV protease inhibitor
DE69430385D1 (en) HIV Protease Inhibitors
NO944208L (en) Novel quinazolines as inhibitors of HIV reverse transcriptase
NO965591L (en) Combination treatment of HIV infection
NO20002481L (en) Combination therapy for the treatment of AIDS
FI970565A (en) HIV protease inhibitory combination