NO941188L - Prevention of allograft repulsion by anti-adhesion molecules - Google Patents

Prevention of allograft repulsion by anti-adhesion molecules

Info

Publication number
NO941188L
NO941188L NO941188A NO941188A NO941188L NO 941188 L NO941188 L NO 941188L NO 941188 A NO941188 A NO 941188A NO 941188 A NO941188 A NO 941188A NO 941188 L NO941188 L NO 941188L
Authority
NO
Norway
Prior art keywords
prevention
adhesion molecules
allograft
antibodies
treatment
Prior art date
Application number
NO941188A
Other languages
Norwegian (no)
Other versions
NO941188D0 (en
Inventor
Mitsuaki Isobe
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1992/008279 external-priority patent/WO1993006864A1/en
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of NO941188D0 publication Critical patent/NO941188D0/en
Publication of NO941188L publication Critical patent/NO941188L/en

Links

Abstract

Det tilveiebringes preparater og metoder for å forlenge funksjonen til et transplantert allograft og forhindre transplantat-frastotning. Spesielt fremkalles toleranse hos et mottager-pattedyr overfor et transplantert organ eller vev ved behandling med et preparat som omfatter mer enn en adhesjons-molekyl-inhibitor som omfatter antistoffer for adhesjonsmolekylet og tilsvarende ligand, f.eks. antistoffer for LFA-1 og ICAM-1. Preparatene ifølge oppfinnelsen kan videre anvendes for behandling av inflammatoriske reaksjoner, så vel som allergier og autoimmunsykdommer.Preparations and methods are provided to extend the function of a transplanted allograft and prevent graft rejection. In particular, tolerance of a recipient mammal to a transplanted organ or tissue is induced by treatment with a composition comprising more than one adhesion molecule inhibitor comprising antibodies to the adhesion molecule and corresponding ligand, e.g. antibodies for LFA-1 and ICAM-1. The compositions of the invention can further be used for the treatment of inflammatory reactions, as well as allergies and autoimmune diseases.

NO941188A 1991-10-01 1994-03-30 Prevention of allograft repulsion by anti-adhesion molecules NO941188L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76804491A 1991-10-01 1991-10-01
PCT/US1992/008279 WO1993006864A1 (en) 1991-10-01 1992-09-29 Preventing allograft rejection with antibodies to adhesion molecules

Publications (2)

Publication Number Publication Date
NO941188D0 NO941188D0 (en) 1994-03-30
NO941188L true NO941188L (en) 1994-05-31

Family

ID=26785050

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941188A NO941188L (en) 1991-10-01 1994-03-30 Prevention of allograft repulsion by anti-adhesion molecules

Country Status (1)

Country Link
NO (1) NO941188L (en)

Also Published As

Publication number Publication date
NO941188D0 (en) 1994-03-30

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