NO940448L - Novel Leukotriene B4 Antagonists, Methods of Preparing Such and Their Use as Pharmaceutical Agents - Google Patents
Novel Leukotriene B4 Antagonists, Methods of Preparing Such and Their Use as Pharmaceutical AgentsInfo
- Publication number
- NO940448L NO940448L NO940448A NO940448A NO940448L NO 940448 L NO940448 L NO 940448L NO 940448 A NO940448 A NO 940448A NO 940448 A NO940448 A NO 940448A NO 940448 L NO940448 L NO 940448L
- Authority
- NO
- Norway
- Prior art keywords
- antagonists
- radical
- pharmaceutical agents
- preparing
- methods
- Prior art date
Links
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Leukotrien-B4-antagonister med formel I (D hvori X representerer C,-C4-alkoksy eller -S(0)p-(C1-C4)-alkyl, p representerer O, l eller 2, Y representerer et hydrogenatom eller radikalet CO-A-COR2, hvori A represen- terer en alkylengruppe med 1-6 C-atomer i kjeden, eller et radikal R! og R2 representerer radikalet OH, -O- ( Cj-C4) -alkyl, -O- ( C3-C6) -sykloalkyl, -O- ( C6-C10) -aryl, -O- ( C7-C12) -aralkyl eller radikalet NR3R4, hvor R3 og R, betegner hydrogen, (Cj-C4 )-alkyl, (C3- C6)-sykloalkyl eller ( C7-C12)-aralkyl så vel som deres salter med fysiologisk forenlige baser og deres syklodekstrin- clathrater, en fremgangsmåte for deres fremstilling og anvendelse som farma- søytiske midler er også beskrevet.Leukotriene B4 antagonists of formula I (D wherein X represents C, -C4 alkoxy or -S (O) p- (C1-C4) alkyl, p represents O, 1 or 2, Y represents a hydrogen atom or radical CO -A-COR2, wherein A represents an alkylene group having 1-6 C atoms in the chain, or a radical R 1 and R 2 represents the radical OH, -O- (C 1 -C 4) alkyl, -O- (C 3 - C6) -cycloalkyl, -O- (C6-C10) -aryl, -O- (C7-C12) -aralkyl or radical NR3R4, wherein R3 and R, represent hydrogen, (C1-C4) -alkyl, ) -cycloalkyl or (C7-C12) -aralkyl as well as their salts with physiologically compatible bases and their cyclodextrin clathrates, a process for their preparation and use as pharmaceutical agents are also described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4127193A DE4127193A1 (en) | 1991-08-15 | 1991-08-15 | NEW LEUKOTRIEN-B (ARROW DOWN) 4 (ARROW DOWN) ANTAGONISTS, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS |
PCT/EP1992/001816 WO1993004056A1 (en) | 1991-08-15 | 1992-08-06 | New leukotriene-b4 antagonists, methods of preparing them and their use as drugs |
Publications (2)
Publication Number | Publication Date |
---|---|
NO940448D0 NO940448D0 (en) | 1994-02-10 |
NO940448L true NO940448L (en) | 1994-02-10 |
Family
ID=25906438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO940448A NO940448L (en) | 1991-08-15 | 1994-02-10 | Novel Leukotriene B4 Antagonists, Methods of Preparing Such and Their Use as Pharmaceutical Agents |
Country Status (1)
Country | Link |
---|---|
NO (1) | NO940448L (en) |
-
1994
- 1994-02-10 NO NO940448A patent/NO940448L/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO940448D0 (en) | 1994-02-10 |
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