NO932120D0 - BIFENYL DERIVATIVES, PHARMACEUTICALS CONTAINING THESE, AND PROCEDURE FOR THEIR PREPARATION - Google Patents

BIFENYL DERIVATIVES, PHARMACEUTICALS CONTAINING THESE, AND PROCEDURE FOR THEIR PREPARATION

Info

Publication number
NO932120D0
NO932120D0 NO932120A NO932120A NO932120D0 NO 932120 D0 NO932120 D0 NO 932120D0 NO 932120 A NO932120 A NO 932120A NO 932120 A NO932120 A NO 932120A NO 932120 D0 NO932120 D0 NO 932120D0
Authority
NO
Norway
Prior art keywords
bifenyl
derivatives
procedure
preparation
pharmaceuticals containing
Prior art date
Application number
NO932120A
Other languages
Norwegian (no)
Other versions
NO932120L (en
Inventor
Helmut Pieper
Frank Himmelsbach
Guenter Linz
Volkhard Austel
Thomas Mueller
Johannes Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO932120D0 publication Critical patent/NO932120D0/en
Publication of NO932120L publication Critical patent/NO932120L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
NO932120A 1992-06-11 1993-06-10 Biphenyl derivatives, drugs containing them, and methods for their preparation NO932120L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4219158A DE4219158A1 (en) 1992-06-11 1992-06-11 Biphenyl derivatives, pharmaceutical compositions containing them and processes for their preparation

Publications (2)

Publication Number Publication Date
NO932120D0 true NO932120D0 (en) 1993-06-10
NO932120L NO932120L (en) 1993-12-13

Family

ID=6460811

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932120A NO932120L (en) 1992-06-11 1993-06-10 Biphenyl derivatives, drugs containing them, and methods for their preparation

Country Status (14)

Country Link
EP (1) EP0574808A1 (en)
JP (1) JPH0673038A (en)
KR (1) KR940005554A (en)
CN (1) CN1080917A (en)
AU (1) AU4120193A (en)
CA (1) CA2098158A1 (en)
DE (1) DE4219158A1 (en)
FI (1) FI932649A (en)
HU (1) HU9301700D0 (en)
IL (1) IL105976A0 (en)
MX (1) MX9303466A (en)
NO (1) NO932120L (en)
PL (1) PL299260A1 (en)
ZA (1) ZA934090B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
ATE202345T1 (en) * 1993-03-29 2001-07-15 Astrazeneca Ab HETEROCYCLIC DERIVATIVES AS PLATE AGGREGATION INHIBITORS
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
AU692439B2 (en) * 1993-03-29 1998-06-11 Zeneca Limited Heterocyclic compounds as platelet aggregation inhibitors
GB9313285D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Acid derivatives
US5463011A (en) * 1993-06-28 1995-10-31 Zeneca Limited Acid derivatives
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
DE4424974A1 (en) * 1994-07-15 1996-01-18 Thomae Gmbh Dr K Urea and carbamic acid derivatives, medicaments containing these compounds and process for their preparation
DE19636689A1 (en) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg New benzamidine derivatives
ID24846A (en) * 1997-11-20 2000-08-24 Teijin Ltd BIFENYLAMIDINE DECLINES
DE19819548A1 (en) * 1998-04-30 1999-11-04 Merck Patent Gmbh Biphenyl derivatives
AU2868601A (en) * 2000-01-27 2001-08-07 Ribotargets Ltd Biaryl compounds, their preparation and their use in therapy
US7534894B2 (en) 2003-09-25 2009-05-19 Wyeth Biphenyloxy-acids
US20090018145A1 (en) * 2004-10-19 2009-01-15 Compass Pharmaceuticals Llc Compositions and their use as anti-tumor agents
EP3026044B8 (en) 2006-06-26 2018-12-19 Akebia Therapeutics, Inc. Prolyl hydroxylase inhibitors and methods of use
WO2012170439A1 (en) 2011-06-06 2012-12-13 The Ohio State University Methods for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
NO2686520T3 (en) 2011-06-06 2018-03-17
CN114404414A (en) 2013-06-13 2022-04-29 阿克比治疗有限公司 Compositions and methods for treating anemia
AR099354A1 (en) 2013-11-15 2016-07-20 Akebia Therapeutics Inc SOLID FORMS OF ACID {[5- (3-CHLOROPHENYL) -3-HYDROXIPIRIDIN-2-CARBON] AMINO} ACETIC, COMPOSITIONS, AND ITS USES
WO2016118858A1 (en) 2015-01-23 2016-07-28 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
BR112017021097B1 (en) 2015-04-01 2024-01-02 Akebia Therapeutics, Inc ORAL DOSAGE FORMULATION AND ITS USE
TWI822776B (en) 2018-05-09 2023-11-21 美商阿克比治療有限公司 Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5084466A (en) * 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
DE4035961A1 (en) * 1990-11-02 1992-05-07 Thomae Gmbh Dr K CYCLIC IMINODERIVATES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE4102024A1 (en) * 1991-01-24 1992-07-30 Thomae Gmbh Dr K BIPHENYL DERIVATIVES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF
ATE125791T1 (en) * 1991-06-11 1995-08-15 Ciba Geigy Ag AMIDINO COMPOUNDS, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS.
DE4127404A1 (en) * 1991-08-19 1993-02-25 Thomae Gmbh Dr K CYCLIC IMINODERIVATES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
DE4219158A1 (en) 1993-12-16
FI932649A (en) 1993-12-12
EP0574808A1 (en) 1993-12-22
CA2098158A1 (en) 1993-12-12
HU9301700D0 (en) 1993-09-28
PL299260A1 (en) 1994-03-07
JPH0673038A (en) 1994-03-15
MX9303466A (en) 1994-01-31
ZA934090B (en) 1994-12-11
FI932649A0 (en) 1993-06-10
IL105976A0 (en) 1993-10-20
AU4120193A (en) 1993-12-23
NO932120L (en) 1993-12-13
KR940005554A (en) 1994-03-21
CN1080917A (en) 1994-01-19

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