NO922345L - PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES - Google Patents

PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES

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Publication number
NO922345L
NO922345L NO92922345A NO922345A NO922345L NO 922345 L NO922345 L NO 922345L NO 92922345 A NO92922345 A NO 92922345A NO 922345 A NO922345 A NO 922345A NO 922345 L NO922345 L NO 922345L
Authority
NO
Norway
Prior art keywords
aryl group
group
alkyl
optionally substituted
pharmacologically active
Prior art date
Application number
NO92922345A
Other languages
Norwegian (no)
Other versions
NO922345D0 (en
Inventor
Colin Bennion
Stephen Connolly
David Hulme Robinson
Original Assignee
Fisons Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898928456A external-priority patent/GB8928456D0/en
Priority claimed from GB909023645A external-priority patent/GB9023645D0/en
Priority claimed from PCT/GB1990/001941 external-priority patent/WO1991008737A2/en
Application filed by Fisons Plc filed Critical Fisons Plc
Publication of NO922345D0 publication Critical patent/NO922345D0/en
Publication of NO922345L publication Critical patent/NO922345L/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelser som har farmakologisk aktivitet, frem- gangsmåte for fremstilling, sammensetninger som inneholder disse og fremgangsmåter for behandling som innbefatter anvendelse av disse. I sitt videste aspekt angår oppfinnelsen forbindelser som har generell formel I der R1 representerer en alkyl C^^g gruppe valgfritt substituert med en arylgruppe eller hydroksy eller en cykloalkyl C3_6 gruppe. R2 representerer en alkyl Cj^g gruppe valgfritt substituert med en arylgruppe, eller R2 representerer en gruppe -CH2-X-R4 der X represen- terer O eller S, og R4 representerer hydrogen, en arylgruppe, eller en alkyl eller alkenyl CI-IQ gruppe valgfritt substituert med en arylgruppe, R3 represen- terer OB, alkoksy C^.fc eller -NER31, der R31 represen- terer hydrogen, alkyl C}.^, OH eller alkoksy C]^ valgfritt substituert med arylgruppe, R5 representerer hydrogen, en arylgruppe eller en alkyl eller alkenyl cl-18 gruppe valgfritt substituert med en arylgruppe, n representerer O, l, 2 eller 3, q representerer O eller l, Y representerer -CHR6- eller -CH=CH-, O eller S, der R^ representerer hydrogen, en arylgruppe eller en alkyl eller en alkenyl C-^jg gruppe valgfritt substituert med en arylgruppe, og farmasøytisk aksepterbare derivater derav.Compounds having pharmacological activity, process for preparation, compositions containing them and methods of treatment which include their use. In its broadest aspect, the invention relates to compounds having general formula I wherein R 1 represents an alkyl C 1-6 group optionally substituted with an aryl group or hydroxy or a cycloalkyl C 3-6 group. R 2 represents an alkyl C 1-6 group optionally substituted with an aryl group, or R 2 represents a group -CH 2 -X-R 4 where X represents O or S and R 4 represents hydrogen, an aryl group, or an alkyl or alkenyl C group optionally substituted with an aryl group, R 3 represents OB, alkoxy C 1-4 or -NER 31, wherein R 31 represents hydrogen, alkyl C 1-4, OH or alkoxy C 1 an aryl group or an alkyl or alkenyl cl-18 group optionally substituted with an aryl group, n represents 0, 1, 2 or 3, q represents O or 1.2, Y represents -CHR6- or -CH = CH-, O or S, where R 2 represents hydrogen, an aryl group or an alkyl or an alkenyl C 1-6 group optionally substituted with an aryl group, and pharmaceutically acceptable derivatives thereof.

NO92922345A 1989-12-16 1992-06-15 PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES NO922345L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898928456A GB8928456D0 (en) 1989-12-16 1989-12-16 Compounds
GB909023645A GB9023645D0 (en) 1990-10-31 1990-10-31 Compounds
PCT/GB1990/001941 WO1991008737A2 (en) 1989-12-16 1990-12-12 Pharmacologically active amide carboxylate derivatives

Publications (2)

Publication Number Publication Date
NO922345D0 NO922345D0 (en) 1992-06-15
NO922345L true NO922345L (en) 1992-06-15

Family

ID=27264850

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92922345A NO922345L (en) 1989-12-16 1992-06-15 PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES

Country Status (1)

Country Link
NO (1) NO922345L (en)

Also Published As

Publication number Publication date
NO922345D0 (en) 1992-06-15

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