NO920024L - PREPARATIONS AND PROCEDURES FOR AA PREVENT FLUOROSE - Google Patents

PREPARATIONS AND PROCEDURES FOR AA PREVENT FLUOROSE

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Publication number
NO920024L
NO920024L NO92920024A NO920024A NO920024L NO 920024 L NO920024 L NO 920024L NO 92920024 A NO92920024 A NO 92920024A NO 920024 A NO920024 A NO 920024A NO 920024 L NO920024 L NO 920024L
Authority
NO
Norway
Prior art keywords
fluoride
monofluorophosphate
fluorosis
ingested
fluorose
Prior art date
Application number
NO92920024A
Other languages
Norwegian (no)
Other versions
NO920024D0 (en
Inventor
Marcus G Grodberg
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Priority to NO92920024A priority Critical patent/NO920024L/en
Publication of NO920024D0 publication Critical patent/NO920024D0/en
Publication of NO920024L publication Critical patent/NO920024L/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Et fluorosefritt, spiselig fluorioninneholdende preparat om- fattende en blanding av farmasøytisk akseptabelt fluorid og monofluorfosfat i et vektforhold for å tilveiebringe ikke mer enn 50 %, og fortrinnsvis ikke mer enn 25 %, tilgjengelige fluorioner fra fluoridet og balansen fra mono- fluorfosfatet. Med "fluorosefritt" pre- parat er ment et preparat som, når det inntas, minimaliserer eller forebygger forekomsten av fluorose som er en van- lig effekt når fluor inntas. Preparatet kan inneholde ytterligere farmasøytisk akseptable adjuvanser, slik som vit- aminer, fargestoffer, smaksstoffer, bærere, stabiliseringsmidler, konser- veringsmidler og medikamenter, og kan foreligge i form av et pulver, tablett, kapsel, pille eller en væske i en egnet spiselig bærer. Foretrukne forbindelser er alkalimetall-, ammonium- og amin- fluorider og monofluorfosfater. De mest foretrukne forbindelser er natrium- fluorid (NaF) og natriummonofluorfosfat (MFP), hvis formel er Na2FP03, og de tilsvarende kaliumsalter. Preparatene er spesielt til- passet anvendelse som et kosttilskudd for vesentlig umiddelbart å tilveie- bringe lave doseringer av fluorioner fra fluoridforbindelsen ved inntak, og en langsom, forlenget frigivelse av fluorioner fra monofluorfosfatet.A fluorose-free, edible fluoride-containing composition comprising a mixture of pharmaceutically acceptable fluoride and monofluorophosphate in a weight ratio to provide no more than 50%, and preferably not more than 25%, available fluoride ions from the fluoride and the balance from the monofluorophosphate. By "fluorosis-free" preparation is meant a preparation which, when ingested, minimizes or prevents the occurrence of fluorosis which is a common effect when fluoride is ingested. The composition may contain additional pharmaceutically acceptable adjuvants, such as vitamins, dyes, flavors, carriers, stabilizers, preservatives and medicaments, and may be in the form of a powder, tablet, capsule, pill or liquid in a suitable edible carrier. . Preferred compounds are alkali metal, ammonium and amine fluorides and monofluorophosphates. The most preferred compounds are sodium fluoride (NaF) and sodium monofluorophosphate (MFP), whose formula is Na2FP03, and the corresponding potassium salts. The compositions are particularly adapted for use as a dietary supplement to provide substantially immediate doses of fluoride ions from the fluoride compound upon ingestion, and a slow, prolonged release of fluoride ions from the monofluorophosphate.

NO92920024A 1992-01-02 1992-01-02 PREPARATIONS AND PROCEDURES FOR AA PREVENT FLUOROSE NO920024L (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO92920024A NO920024L (en) 1992-01-02 1992-01-02 PREPARATIONS AND PROCEDURES FOR AA PREVENT FLUOROSE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO92920024A NO920024L (en) 1992-01-02 1992-01-02 PREPARATIONS AND PROCEDURES FOR AA PREVENT FLUOROSE

Publications (2)

Publication Number Publication Date
NO920024D0 NO920024D0 (en) 1992-01-02
NO920024L true NO920024L (en) 1993-07-05

Family

ID=19894739

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92920024A NO920024L (en) 1992-01-02 1992-01-02 PREPARATIONS AND PROCEDURES FOR AA PREVENT FLUOROSE

Country Status (1)

Country Link
NO (1) NO920024L (en)

Also Published As

Publication number Publication date
NO920024D0 (en) 1992-01-02

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