NO914667L - PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLED DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLED DERIVATIVES

Info

Publication number
NO914667L
NO914667L NO91914667A NO914667A NO914667L NO 914667 L NO914667 L NO 914667L NO 91914667 A NO91914667 A NO 91914667A NO 914667 A NO914667 A NO 914667A NO 914667 L NO914667 L NO 914667L
Authority
NO
Norway
Prior art keywords
aryled
derivatives
procedure
preparation
therapeutic active
Prior art date
Application number
NO91914667A
Other languages
Norwegian (no)
Other versions
NO914667D0 (en
Inventor
Robert Ian Dowell
Philip Neil Edwards
Keith Oldham
Original Assignee
Ici Pharma
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma, Ici Plc filed Critical Ici Pharma
Publication of NO914667D0 publication Critical patent/NO914667D0/en
Publication of NO914667L publication Critical patent/NO914667L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
NO91914667A 1990-11-28 1991-11-27 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLED DERIVATIVES NO914667L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90403377 1990-11-28
EP91402536 1991-09-24

Publications (2)

Publication Number Publication Date
NO914667D0 NO914667D0 (en) 1991-11-27
NO914667L true NO914667L (en) 1992-05-29

Family

ID=26127543

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914667A NO914667L (en) 1990-11-28 1991-11-27 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLED DERIVATIVES

Country Status (16)

Country Link
US (2) US5225438A (en)
EP (1) EP0488602A1 (en)
JP (1) JPH04283577A (en)
KR (1) KR920009816A (en)
AU (1) AU645363B2 (en)
CA (1) CA2055530A1 (en)
CS (1) CS360891A3 (en)
FI (1) FI915507A (en)
GB (1) GB9124825D0 (en)
IE (1) IE913866A1 (en)
IL (1) IL99987A (en)
MY (1) MY131013A (en)
NO (1) NO914667L (en)
NZ (1) NZ240491A (en)
PT (1) PT99627A (en)
RU (1) RU2067976C1 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254581A (en) * 1990-06-21 1993-10-19 Imperial Chemical Industries Plc Pyran derivatives and their use as inhibitors of 5-lipoxygenase
IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
IL100483A0 (en) * 1991-01-17 1992-09-06 Ici Plc Sulphonamide derivatives
EP0532239B1 (en) * 1991-09-10 1995-12-13 Zeneca Limited Benzenesulphonamide derivatives as 5-lipoxygenase inhibitors
GB9300894D0 (en) * 1992-02-07 1993-03-10 Zeneca Ltd Oxime derivatives
CA2094465A1 (en) * 1992-04-23 1993-10-24 Pierre Andre Raymond Bruneau Cycloalkane derivatives
CA2095005A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Hydroxylamine derivatives
CA2095006A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Oxime derivatives
AU4444393A (en) * 1992-09-01 1994-03-10 Zeneca Limited Pyrrolidine derivatives
ES2055657B1 (en) * 1992-10-08 1995-02-16 Ici Plc BENZENE SULFONAMIDE DERIVATIVES.
US5298627A (en) * 1993-03-03 1994-03-29 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
IL109254A (en) * 1993-04-29 1999-03-12 Zeneca Ltd Tetrahydropyran and tetrahydrofuran ether derivatives their preparation and pharmaceutical compositions comprising them
US5346914A (en) * 1993-05-14 1994-09-13 Abbott Laboratories (4-alkoxypyran-4-yl) substituted arylalkylaryl-, arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase
BR9406822A (en) * 1993-06-14 1996-03-26 Pfizer Lipidoxygenase imidazole inhibitors
US5360815A (en) * 1993-06-23 1994-11-01 Merck Frosst Canada, Inc. Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis
KR100239930B1 (en) * 1994-10-18 2000-03-02 디. 제이. 우드, 스피겔 알렌 제이 5-lipoxygenase inhibitors
SK281577B6 (en) * 1994-10-18 2001-05-10 Pfizer Inc. Heterocyclic compositions and pharmaceutical agent based on them
US5883106A (en) * 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
US6063928A (en) * 1994-10-18 2000-05-16 Pfizer Inc 5-lipoxygenase inhibitors
US5527827A (en) * 1994-10-27 1996-06-18 Merck Frosst Canada, Inc. Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis
US5622948A (en) * 1994-12-01 1997-04-22 Syntex (U.S.A.) Inc. Pyrrole pyridazine and pyridazinone anti-inflammatory agents
US5670526A (en) * 1995-12-21 1997-09-23 Otsuka Pharmaceutical Co., Ltd. 1,3,4-oxadiazoles
CN1136197C (en) * 1996-05-30 2004-01-28 霍夫曼-拉罗奇有限公司 Novel pyridajinone derivatives
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
ATE515493T1 (en) * 2003-03-31 2011-07-15 Council Scient Ind Res MERCAPTOPHENYLNAPHTHYLMETHANE DERIVATIVES AND THEIR PRODUCTION
DE102004007358B4 (en) * 2004-02-16 2017-10-12 Chiron As Congeners, chlorinated, brominated and / or iodinated fluorinated aromatic compounds containing two benzene rings in their basic structure, process for their preparation and their use
EP2332527A3 (en) 2004-10-20 2011-11-16 Resverlogix Corp. Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases
AU2006275514B2 (en) 2005-07-29 2012-04-05 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
RS20090211A (en) * 2006-11-27 2010-10-31 Pfizer Products Inc. Pyrazole analogs
PT2118074E (en) 2007-02-01 2014-03-20 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular diseases
CA2680139A1 (en) * 2007-03-05 2008-09-12 Biolipox Ab New methylenebisphenyl compounds useful in the treatment of inflammation
EP2225229A1 (en) * 2007-11-26 2010-09-08 Pfizer Inc. Pyrazole derivatives as 5-lo inhibitors
CA2711103C (en) 2008-06-26 2016-08-09 Resverlogix Corp. Methods of preparing quinazolinone derivatives
CA2747417C (en) 2009-01-08 2017-01-03 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
CA3146333A1 (en) 2009-03-18 2010-09-23 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
LT2421533T (en) 2009-04-22 2018-12-27 Resverlogix Corp. Novel anti-inflammatory agents
JP5992049B2 (en) 2011-11-01 2016-09-14 レスバーロジックス コーポレイション Oral immediate release formulations for substituted quinazolinones
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
CN103724207B (en) * 2013-12-20 2016-07-06 北京智博高科生物技术有限公司 Phenylbenzyl ether derivative and its preparation method and application
WO2016147053A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3661917A (en) * 1970-05-21 1972-05-09 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols
US3743737A (en) * 1970-05-21 1973-07-03 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions
US4567184A (en) * 1982-12-01 1986-01-28 Usv Pharmaceutical Corporation Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies
US4794188A (en) * 1982-12-01 1988-12-27 Usv Pharmaceutical Corporation Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
US4625034A (en) * 1985-02-04 1986-11-25 Usv Pharmaceutical Corp. 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4728668A (en) * 1985-04-16 1988-03-01 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4876346A (en) * 1985-05-02 1989-10-24 American Home Products Corporation Quinoline compounds
EP0271287A3 (en) * 1986-12-11 1990-06-13 Merck Frosst Canada Inc. Quinoline dioic acids and amides
US4920130A (en) * 1987-11-02 1990-04-24 Rorer Pharamceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920133A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920132A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920131A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4918081A (en) * 1988-06-20 1990-04-17 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene d4
EP0349062A1 (en) * 1988-06-27 1990-01-03 Merck Frosst Canada Inc. Quinoline ether alkanoic acid
US4943586A (en) * 1988-12-14 1990-07-24 Arizona Board Of Regents For The University Of Arizona Pyrazole-containing juvenile hormone mimics for pest control, compositions and use
GB8926981D0 (en) * 1988-12-23 1990-01-17 Ici Plc Heterocyclic derivatives
IE64358B1 (en) * 1989-07-18 1995-07-26 Ici Plc Diaryl ether heterocycles
GB9018134D0 (en) * 1989-09-29 1990-10-03 Ici Plc Heterocyclic derivatives

Also Published As

Publication number Publication date
EP0488602A1 (en) 1992-06-03
FI915507A (en) 1992-05-29
CS360891A3 (en) 1992-06-17
AU645363B2 (en) 1994-01-13
RU2067976C1 (en) 1996-10-20
FI915507A0 (en) 1991-11-22
IL99987A0 (en) 1992-08-18
CA2055530A1 (en) 1992-05-29
NO914667D0 (en) 1991-11-27
IE913866A1 (en) 1992-06-03
NZ240491A (en) 1994-01-26
KR920009816A (en) 1992-06-25
PT99627A (en) 1992-10-30
GB9124825D0 (en) 1992-01-15
IL99987A (en) 1996-10-16
US5225438A (en) 1993-07-06
US5276037A (en) 1994-01-04
JPH04283577A (en) 1992-10-08
MY131013A (en) 2007-07-31
AU8702991A (en) 1992-06-04

Similar Documents

Publication Publication Date Title
NO914667D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLED DERIVATIVES
NO914036D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE QUINAZOLINE DERIVATIVES
NO904694L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES.
NO901684D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 3-SUBSTITUTED-2-OXINDOL DERIVATIVES.
NO172801C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE KINUCLIDINE DERIVATIVES
NO883974D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDRO-HYDROXYPYRANON DERIVATIVES.
NO903088D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES.
NO904986D0 (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES.
NO172575C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZOCYCLYLKANE DERIVATIVES
NO900697D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ACETAMIDE DERIVATIVES.
NO171857C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 2'-HALOMETHYLIDEEN-ADENOSINE DERIVATIVES
NO891723L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHINAZOLINE DERIVATIVES.
NO173061C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 2-BENZOTIAZOLINES
NO914071D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RELATIONS
NO172802C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TIENOPYRANES
NO913187D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TRICYCLIC DERIVATIVES.
NO900972D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE NAFTALEN DERIVATIVES.
NO900942D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AZACYCLOOKTADIEN DERIVATIVES.
NO169589C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAAZAACENAFETYLENE DERIVATIVES
NO890519D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PROPANON DERIVATIVES.
NO904470D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZODIAZEPINE DERIVATIVES.
NO169486C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ALLYLAMINOETYLAZOLES
NO891677D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PHENETANOLAMINE DERIVATIVES.
NO890506L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHLORANILIN DERIVATIVES.
NO173140C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE TIENO-TRIAZOLO-DIAZEPINE DERIVATIVES