NO903307L - PARAMAGNETIC CONNECTIONS. - Google Patents

PARAMAGNETIC CONNECTIONS.

Info

Publication number
NO903307L
NO903307L NO90903307A NO903307A NO903307L NO 903307 L NO903307 L NO 903307L NO 90903307 A NO90903307 A NO 90903307A NO 903307 A NO903307 A NO 903307A NO 903307 L NO903307 L NO 903307L
Authority
NO
Norway
Prior art keywords
group
paramagnetic
connections
linker
compounds
Prior art date
Application number
NO90903307A
Other languages
Norwegian (no)
Other versions
NO903307D0 (en
Inventor
Jo Klaveness
Paal Rongved
Per Strande
Original Assignee
Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888801646A external-priority patent/GB8801646D0/en
Application filed by Nycomed As filed Critical Nycomed As
Publication of NO903307L publication Critical patent/NO903307L/en
Publication of NO903307D0 publication Critical patent/NO903307D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

Det er gitt paramagnetiske forbindelser som omfatter en paramagnetisk metalltype chelatert ved en chelaterende del bundet av en amidgruppe til en linkergruppe som selv er bundet av en estergruppe til et makromolekyl, hvori nevnte linkergruppe gir en karbonkjede på minst to atomer mellom nevnte amidgruppe og nevnte estergruppe. De nye forbindelsene er spesielt egnet som kontrastmidler, f.eks. i magnetisk resonansavbildning.Paramagnetic compounds are provided which comprise a paramagnetic metal type chelated at a chelating moiety bonded by an amide group to a linker group itself bonded by an ester group to a macromolecule, wherein said linker group provides a carbon chain of at least two atoms between said amide group and said group. The new compounds are particularly suitable as contrast agents, e.g. in magnetic resonance imaging.

NO903307A 1988-01-26 1990-07-25 PARAMAGNETIC CONNECTIONS. NO903307D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888801646A GB8801646D0 (en) 1988-01-26 1988-01-26 Chemical compounds
PCT/EP1989/000078 WO1989006979A1 (en) 1988-01-26 1989-01-26 Paramagnetic compounds

Publications (2)

Publication Number Publication Date
NO903307L true NO903307L (en) 1990-07-25
NO903307D0 NO903307D0 (en) 1990-07-25

Family

ID=26069637

Family Applications (1)

Application Number Title Priority Date Filing Date
NO903307A NO903307D0 (en) 1988-01-26 1990-07-25 PARAMAGNETIC CONNECTIONS.

Country Status (3)

Country Link
AU (1) AU623901B2 (en)
DE (1) DE68901924T2 (en)
NO (1) NO903307D0 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU628403B2 (en) * 1988-09-29 1992-09-17 Access Pharmaceuticals, Inc. Methods and compositions for magnetic resonance imaging
DE10040381C1 (en) * 2000-08-11 2002-06-06 Schering Ag Perfluoroalkyl-containing complexes with sugar residues, process for their preparation and their use
US6641797B2 (en) 2000-08-11 2003-11-04 Schering Aktiengesellschaft Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use
DE102014016901B4 (en) * 2014-09-17 2021-08-12 Friedrich-Schiller-Universität Jena Process for the production of new dextran derivatives as active ingredient carrier systems and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002893A1 (en) * 1985-11-18 1987-05-21 Board Of Regents, The University Of Texas System Polychelating agents for image and spectral enhancement (and spectral shift)
PT90959B (en) * 1988-06-24 1995-05-04 Dow Chemical Co PROCESS FOR THE PREPARATION OF BIFUNCTIONAL MACROCYCLIC CHELANTES, OF THEIR COMPLEXES AND THEIR CONJUGATES WITH ANTIBODIES
DK169306B1 (en) * 1989-06-14 1994-10-10 Af 18 Juni 1990 As Means for removing or inactivating unwanted components in blood or other extracellular body fluids and method of preparing dextran-O-carbonyl-benzo-18-crown-6 and of dextran-hydroxyethylbenzo-18-crown-6

Also Published As

Publication number Publication date
DE68901924T2 (en) 1992-12-10
AU3216289A (en) 1989-08-25
AU623901B2 (en) 1992-05-28
DE68901924D1 (en) 1992-07-30
NO903307D0 (en) 1990-07-25

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