NO891231L - CEPHALOSPORIN DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF. - Google Patents

CEPHALOSPORIN DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF.

Info

Publication number
NO891231L
NO891231L NO89891231A NO891231A NO891231L NO 891231 L NO891231 L NO 891231L NO 89891231 A NO89891231 A NO 89891231A NO 891231 A NO891231 A NO 891231A NO 891231 L NO891231 L NO 891231L
Authority
NO
Norway
Prior art keywords
procedures
preparing
cephalosporin derivatives
derivatives
cefemder
Prior art date
Application number
NO89891231A
Other languages
Norwegian (no)
Other versions
NO891231D0 (en
Inventor
Friedhelm Adam
Walter Duerckheimer
Gerd Fischer
Burghard Mencke
Hubert Selinger
Dieter Isert
Norbert Klesel
Gerhard Seibert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO891231D0 publication Critical patent/NO891231D0/en
Publication of NO891231L publication Critical patent/NO891231L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Det er beskrevet cefemkarboksylsyreestere av den generelle formelen. hvori Rog Rbetyr Cfc-alkyl og HO-gruppen står 1 syn-poslsjon. Det er videre angitt fremgangsmåter for fremstilling av cefemderlvatene. Forbindelsene viser aktivitet mot bakterielle infeksjoner og kan anvendes 1 farmasøytiske preparater.Cephemcarboxylic acid esters of the general formula are described. wherein Rog R represents Cfc-alkyl and the HO group stands 1 syn-position. Processes for the preparation of the cefemder derivatives are further stated. The compounds show activity against bacterial infections and can be used in pharmaceutical preparations.

NO89891231A 1988-03-22 1989-03-21 CEPHALOSPORIN DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF. NO891231L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3809561A DE3809561A1 (en) 1988-03-22 1988-03-22 ESTER OF 7- (2- (2-AMINOTHIAZOL-4-YL) -2- (Z) - HYDROXYIMINOACETAMIDO) -3-METHOXYMETHYL-3-CEPHEM-4-CARBONIC ACID, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL ACCESSORIES CONTAINING IT

Publications (2)

Publication Number Publication Date
NO891231D0 NO891231D0 (en) 1989-03-21
NO891231L true NO891231L (en) 1989-09-25

Family

ID=6350344

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89891231A NO891231L (en) 1988-03-22 1989-03-21 CEPHALOSPORIN DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF.

Country Status (14)

Country Link
EP (1) EP0334281A3 (en)
JP (1) JPH01283290A (en)
KR (1) KR890014560A (en)
CN (1) CN1036770A (en)
AU (1) AU613164B2 (en)
DE (1) DE3809561A1 (en)
DK (1) DK138789A (en)
FI (1) FI891304A (en)
HU (1) HUT49615A (en)
IL (1) IL89679A0 (en)
NO (1) NO891231L (en)
NZ (1) NZ228403A (en)
PT (1) PT90065B (en)
ZA (1) ZA892089B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3804841A1 (en) * 1988-02-17 1989-08-31 Hoechst Ag CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE3919259A1 (en) * 1989-06-13 1990-12-20 Hoechst Ag CRYSTALLINE CEPHEM ACID ADDITION SALTS AND METHOD FOR THE PRODUCTION THEREOF
TW212181B (en) * 1992-02-14 1993-09-01 Hoechst Ag
ATE164378T1 (en) * 1992-05-21 1998-04-15 Hoechst Ag METHOD FOR CLEAVING CEPHALOSPORIN PRODRUG ESTERS TO 7-AMINO-3-METHOXYMETHYLCEPH-3-EM-4-CARBONIC ACID
CN101245077B (en) * 2007-02-14 2010-06-02 山东轩竹医药科技有限公司 Novel cephalosporin derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575803A (en) * 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
DE2716677C2 (en) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephem derivatives and processes for their preparation
DE3021373A1 (en) * 1980-06-06 1981-12-17 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING 2- (2-AMINOTHIAZOL-4-YL) -N- (IMIDAZOLIDIN-2-ON-1-YL) 2-IMINOACETYLCEPHALOSPORINES OF THE SYN FORM
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
DE3804841A1 (en) * 1988-02-17 1989-08-31 Hoechst Ag CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
DK138789A (en) 1989-09-23
AU3153289A (en) 1989-09-28
EP0334281A2 (en) 1989-09-27
NO891231D0 (en) 1989-03-21
EP0334281A3 (en) 1991-08-28
ZA892089B (en) 1989-10-25
KR890014560A (en) 1989-10-24
IL89679A0 (en) 1989-09-28
PT90065B (en) 1994-05-31
CN1036770A (en) 1989-11-01
PT90065A (en) 1989-11-10
DE3809561A1 (en) 1989-10-05
JPH01283290A (en) 1989-11-14
DK138789D0 (en) 1989-03-21
NZ228403A (en) 1990-10-26
FI891304A (en) 1989-09-23
AU613164B2 (en) 1991-07-25
HUT49615A (en) 1989-10-30
FI891304A0 (en) 1989-03-20

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