NO883205L

NO883205L - MOISTURE RESISTANT SKIN TREATMENT PREPARATIONS.

Info

Publication number: NO883205L
Application number: NO883205A
Authority: NO
Inventors: Arthur C W Georgalas
Original assignee: Ritz Group Ltd Charles
Priority date: 1986-12-08
Filing date: 1988-07-19
Publication date: 1988-07-27
Also published as: NO883205D0

Description

T eknisk områdeT echnical area

Den foreliggende oppfinnelse angår hudbehandlingspreparater og fremgangsmåter for fremstilling av samme, såsom solfilterpreparater og fuktighetspreparater med forbedret substantivitet. The present invention relates to skin treatment preparations and methods for producing the same, such as sunscreen preparations and moisturizing preparations with improved substantivity.

BakgrunnsteknikkBackground technology

Markedet oversvømmes med solfilter- og solsperrepreparater. Disse produkter gir utmerket beskyttelse mot alvor- The market is flooded with sun filter and sunscreen preparations. These products provide excellent protection against serious

lig forbrenning av hud som utsettes for solen, og inneholder kjemikalier som er i stand til å absorbere ultrafiolett lys av ulike bølgelengder, som f.eks. 2-hydroxy-4-methoxybenzo-fenon, eller et ugjennomskinnelig materiale som fysisk reflek-terer eller sprer ultrafiolett lys, som f.eks. sinkoxyd eller titandioxyd. De fleste av disse preparater gir solbeskyttelse i lengre tid, så lenge de forblir på huden og ikke vaskes vekk ved bading. similar to burning of skin exposed to the sun, and contains chemicals capable of absorbing ultraviolet light of various wavelengths, such as e.g. 2-hydroxy-4-methoxybenzo-phenone, or an opaque material which physically reflects or scatters ultraviolet light, such as e.g. zinc oxide or titanium dioxide. Most of these preparations provide sun protection for a longer period of time, as long as they remain on the skin and are not washed away when bathing.

Uheldigvis vil bading i svømmebassengvann eller sjøvann van-ligvis resultere i at de fleste konvensjonelle solfilter- Unfortunately, bathing in swimming pool water or sea water will usually result in most conventional sun filters

og solsperrepreparater vaskes vekk fra huden, slik at partier av huden blir liggende bare. Det er blitt gjort forsøk på and sunscreen preparations are washed away from the skin, leaving parts of the skin exposed. Attempts have been made

å fremstille solfilterprodukter som er fuktighetsresistente,to produce solar filter products that are moisture resistant,

se f.eks. US patentskrift nr. 3 666 732.see e.g. US Patent No. 3,666,732.

I US patentskrift nr. 4 597 963 beskrives fuktighetsresistente hudbehandlingspreparater, som f.eks. solfilterpreparater, som inneholder en polyvinylalkyl- eller polyvinyl-alkenylester, som f.eks. polyvinylstearat, for å forbedre fuktighetsresistensen eller substantiviteten. US Patent No. 4,597,963 describes moisture-resistant skin treatment preparations, such as e.g. solar filter preparations, which contain a polyvinyl alkyl or polyvinyl alkenyl ester, such as e.g. polyvinyl stearate, to improve moisture resistance or substantivity.

Presentasjon av oppfinnelsenPresentation of the invention

I hnehold til den foreliggende oppfinnelse tilveiebrin-ges et fuktighetsresistent hudbehandlingspreparat i form av et solfilterpreparat eller fuktighetspreparat, i form av en olje-i-vann-emulsjon eller en vann-i-olje-emulsjon, bestående i det vesentlige av fra ca. 50 til 90 vekt% vann, fra ca. According to the present invention, a moisture-resistant skin treatment preparation is provided in the form of a sun filter preparation or moisturizing preparation, in the form of an oil-in-water emulsion or a water-in-oil emulsion, consisting essentially of from approx. 50 to 90% by weight water, from approx.

1 til ca. 10 vekt% mykgjørende middel, fra ca. 1 til ca. 10 1 to approx. 10% by weight softener, from approx. 1 to approx. 10

vekt% emulgeringsmiddel, et konserveringsmiddel og et sekundært amid med strukturen: wt% emulsifier, a preservative and a secondary amide with the structure:

hvor R^og R_ er like eller ulike og betegner mettede eller umettede fettsyrerester inneholdende 8-36 carbonatomer og 0-3 dobbeltbindinger samt 0-1 hydroxylgruppe, i en mengde i området fra ca. 0,5 til 10 vekt%, beregnet på det totale preparat, for å bibringe preparatet fuktighetsresistens. where R^ and R_ are the same or different and denote saturated or unsaturated fatty acid residues containing 8-36 carbon atoms and 0-3 double bonds as well as 0-1 hydroxyl group, in an amount in the range from approx. 0.5 to 10% by weight, calculated on the total preparation, to give the preparation moisture resistance.

I henhold til den foreliggende oppfinnelse tilveiebrin-ges det ytterligere en fremgangsmåte for å forbedre fuktighets-resistensegenskapene av et solfilterpreparat som inneholder ett eller flere UV-absorberende midler, hvilken fremgangsmåte omfatter det trekk at det innlemmes minst ca. 0,5 vekt% av et sekundært amid med strukturen: According to the present invention, a further method is provided for improving the moisture resistance properties of a solar filter preparation containing one or more UV absorbing agents, which method comprises the feature of incorporating at least approx. 0.5% by weight of a secondary amide with the structure:

hvor R^og R2er like eller ulike og betegner mettede eller umettede fettsyreestere inneholdende 8-36 carbonatomer og 0-3 dobbeltbindinger samt 0-1 hydroxylgruppe. where R1 and R2 are the same or different and denote saturated or unsaturated fatty acid esters containing 8-36 carbon atoms and 0-3 double bonds and 0-1 hydroxyl group.

Beste utførelse av oppfinnelsenBest embodiment of the invention

I henhold til den foreliggende oppfinnelse tilveiebrin-ges fuktighetsresistente hudbehandlingspreparater, som f.eks. solfilter- og solsperrepreparater og fuktighetspreparater, hvilke preparater oppviser forbedret fuktighetsresistens og substantivitet som følge av tilstedeværelsen i disse av ett eller flere sekundære amider og inneholder vann, mykgjørende midler, emulgeringsmidler, fortykningsmidler, konserveringsmidler, fargemidler, luktstoffer, antioxydasjonsmidler og lignende samt ett eller flere kjente UV-absorberende forbindelser (når det dreier seg om solfilter- eller solsperrepreparater). Fuktighetspreparatene ifølge oppfinnelsen vil ligne solfilter- og solsperrepreparatene med hensyn til sammensetning, bortsett fra at de eventuelt ikke inneholder noen UV-absorberende forbindelse. According to the present invention, moisture-resistant skin treatment preparations are provided, such as e.g. sun filter and sunscreen preparations and moisturizing preparations, which preparations exhibit improved moisture resistance and substantivity as a result of the presence in them of one or more secondary amides and contain water, emollients, emulsifiers, thickeners, preservatives, coloring agents, fragrances, antioxidants and the like as well as one or more known UV-absorbing compounds (in the case of sun filter or sunscreen preparations). The moisture preparations according to the invention will be similar to the sun filter and sunscreen preparations with regard to composition, except that they may not contain any UV-absorbing compound.

Preparatet ifølge oppfinnelsen er fortrinnsvis en emulsjon av olje-i-vann-typen, da denne type emulsjon gir bedre kosmetisk hudfølelse. Imidlertid kan produktet også fremstilles som vann-i-olje-emulsjon, krembasis eller oljebasis. Avhengig av valget av bestanddeler får preparatet en halvfast, kremlignende konsistens som gjør at det kan fylles på plast-tuber,. eller det får konsistens som losjon, i hvilken form det kan pakkes i en utpresningsbeholder av plast. Beholderen kan innbefatte kork av typen som gir utstrømning eller en utdeler av pumpetypen. The preparation according to the invention is preferably an emulsion of the oil-in-water type, as this type of emulsion provides a better cosmetic skin feel. However, the product can also be prepared as a water-in-oil emulsion, cream base or oil base. Depending on the choice of ingredients, the preparation has a semi-solid, cream-like consistency that allows it to be filled into plastic tubes. or it takes on the consistency of a lotion, in which form it can be packaged in a plastic squeeze container. The container may include an outflow type stopper or a pump type dispenser.

Kjernen i den foreliggende oppfinnelse består i anven-delse av ett eller flere sekundære amider, som denfor defi-nert, som har til hensikt å forbedre fuktighetsresistensen av det angjeldende preparat. Således vil preparatet ifølge oppfinnelsen, uansett hvorvidt det utgjøres av et solsikte-preparat, solsperrepreparat, fuktighetspreparat, osv., inneholde fra ca. 0,5 til ca. 10% og fortrinnsvis fra ca. 1 til ca. 8 vekt% (beregnet på preparatets totalvekt) sekundært amid. Når de benyttes mindre enn 0,5 vekt% sekundært amid, vil den bibragte fuktighetsresistens bli minimal og uaksep-tabel, mens økningen i den bibragte fuktighetsresistens - der-som det benyttes mengder større enn 10 vekt% - vil være mini-male og ikke vil kunne forsvares i betraktning av forbruket av involverte råmaterialer. The core of the present invention consists in the use of one or more secondary amides, as defined therefor, which are intended to improve the moisture resistance of the preparation in question. Thus, the preparation according to the invention, regardless of whether it consists of a sunscreen preparation, sunscreen preparation, moisturizing preparation, etc., will contain from approx. 0.5 to approx. 10% and preferably from approx. 1 to approx. 8% by weight (calculated on the total weight of the preparation) secondary amide. When less than 0.5% by weight of secondary amide is used, the imparted moisture resistance will be minimal and unacceptable, while the increase in the imparted moisture resistance - where amounts greater than 10% by weight - will be minimal and not will be defensible in view of the consumption of raw materials involved.

De sekundære amider som er anvendelige i henhold til den foreliggende oppfinnelse for å bibringe solfilterpreparater forbedret substantivitet, har strukturen: The secondary amides which are applicable according to the present invention to provide solar filter preparations with improved substantivity, have the structure:

hvor og R2er like eller ulike og betegner mettede eller umettede fettsyreestere inneholdende 8-36 carbonatomer, fortrinnsvis 12-22 carbonatomer, og 0-3 dobbeltbindinger samt 0-1 eller flere hydroxylgrupper. where and R2 are the same or different and denote saturated or unsaturated fatty acid esters containing 8-36 carbon atoms, preferably 12-22 carbon atoms, and 0-3 double bonds as well as 0-1 or more hydroxyl groups.

Disse fåes i handelen og kan fremstilles etter konvensjonelle metoder. These are commercially available and can be produced using conventional methods.

Eksempler på sekundære fettamider som egner seg forExamples of secondary fatty amides suitable for

det foreliggende formål, innbefatter, men er ikke begrenset til, N-stearylstearamid, N-stearylerucamid, N-stearyl-12-hydroxystearamid, N-erucylerucamid, N-oleyl-palmitamid, N-oleyl-hyd-roxypalmitamid, N-stearyloleamid, N-erucylstearamid, N-stearyl-hydroxyoleamid, N-oleyloleamid, N-palmitylpalmitamid, N-oleyl-hydroxyoleamid, N-behenylbehenamid, N-behenylerucamid, N-oleyl-hydroxystearamid, N-oleylstearamid, N-oleylbehena- the present purpose, includes, but is not limited to, N-stearyl stearamide, N-stearyl erucamide, N-stearyl-12-hydroxystearamide, N-erucylerucamide, N-oleyl-palmitamide, N-oleyl-hydroxypalmitamide, N-stearyl oleamide, N-erucyl stearamide, N-stearyl hydroxyoleamide, N-oleyl oleamide, N-palmityl palmitamide, N-oleyl hydroxyoleamide, N-behenyl behenamide, N-behenylerucamide, N-oleyl hydroxy stearamide, N-oleyl stearamide, N-oleyl behena-

mid, N-erucylbehehamid, N-caprylstearamid, N-laurylmyristamid, N-margarylarachidamid, N-lauryl-hydroxymyristamid, N-tricosa-nyl-nonadecanamid og lignende. mid, N-erucylbehehamide, N-caprylstearamide, N-laurylmyristamide, N-margarylarachidamide, N-lauryl-hydroxymyristamide, N-tricosa-nyl-nonadecanamide and the like.

Når preparatet er et solfilter- eller solsperrepreparat, vil det inneholde ett eller flere kjente UV-absorberende midler, fortrinnsvis minst én forbindelse som absorberer i UV-B-området (bølgelengder 290-320 nanometer) og minst én forbindelse som absorberer i UV-A-området (bølgelengder 320-400 nanometer). Den totale mengde UV-absorberende midler som innlemmes i preparatet, vil være fra ca. 3 vekt% til ca. 15 vekt%, hvilken mengde vil avgjøre hvorvidt preparatet vil være et solfilterpreparat eller et solsperrepreparat. When the preparation is a sun filter or sunscreen preparation, it will contain one or more known UV absorbing agents, preferably at least one compound that absorbs in the UV-B range (wavelengths 290-320 nanometers) and at least one compound that absorbs in UV-A range (wavelengths 320-400 nanometers). The total amount of UV absorbing agents incorporated into the preparation will be from approx. 3% by weight to approx. 15% by weight, which amount will determine whether the preparation will be a sun filter preparation or a sunscreen preparation.

Egnede UV-A-absorberende midler innbefatter 2-(2'-hyd-roxy-5<1->methylfenyl)-benzotriazol ("Tinuvin P"), 2-(2'-hyd-roxy-5'-t-octylfenyl)-benzotriazol ("Spectra-Sorb UV 5411"), 2,4-dihydroxybenzofenon ("Uvinul 400"), 2-hydroxy-4-methoxy-benzofenon (oxybenzon, "Spectra-Sorb UV9", "Uvinul M-40"), 2,2<1>,4,4<1->tetrahydroxybenzofenon ("Uvinul D50"), 2,2'-dihyd-roxy-4,4<1->dimethoxybenzofenon ("Uvinul D49"), 2,2'-dihydroxy-4-methoxybenzofenon (dioxybenzon, "Spectra-Sorb UV24"), 2-ethyl-hexyl-4-fenyl-benzofenon-carbonat ("Eusolex 3573"), 2-hydro-xy-4-methoxy-4<1->methylbenzofenon (mexenon, "Uvistat 2211"), 2-hydroxy-4-(n-octyloxy)-benzofenon (octabenzon, "Spectra-Sorb UV531"), 4-fenylbenzofenon ("Eusolex 3490") og 2-ethylhexyl-2-cyano-3,3<1->difenylacrylat ("Uvinul N539"). Det eller de UV-A-absorberende midler er tilstede i det ferdige produkt i en mengde av fra ca. 0,5 vekt% til ca. 10 vekt% av preparatet. Mengden vil variere med midlet som velges og i henhold til hvorvidt preparatet er ment å skulle redusere bruningen til et minimum eller å tillate bruning. Det foretrukne UV-A-absorberende middel er 2-hydroxy-4-methoxybenzofenon, alene eller i kombinasjon med 2,2'-dihydroxy-4-methoxybenzofenon. Suitable UV-A absorbents include 2-(2'-hydroxy-5<1->methylphenyl)-benzotriazole ("Tinuvin P"), 2-(2'-hydroxy-5'-t-octylphenyl )-benzotriazole ("Spectra-Sorb UV 5411"), 2,4-dihydroxybenzophenone ("Uvinul 400"), 2-hydroxy-4-methoxy-benzophenone (oxybenzone, "Spectra-Sorb UV9", "Uvinul M-40" ), 2,2<1>,4,4<1->tetrahydroxybenzophenone ("Uvinul D50"), 2,2'-dihydroxy-4,4<1->dimethoxybenzophenone ("Uvinul D49"), 2, 2'-dihydroxy-4-methoxybenzophenone (dioxybenzone, "Spectra-Sorb UV24"), 2-ethyl-hexyl-4-phenyl-benzophenone carbonate ("Eusolex 3573"), 2-hydroxy-4-methoxy-4 <1->methylbenzophenone (mexenon, "Uvistat 2211"), 2-hydroxy-4-(n-octyloxy)-benzophenone (octabenzone, "Spectra-Sorb UV531"), 4-phenylbenzophenone ("Eusolex 3490") and 2- ethylhexyl-2-cyano-3,3<1->diphenyl acrylate ("Uvinul N539"). The UV-A absorbing agent(s) are present in the finished product in an amount of from approx. 0.5% by weight to approx. 10% by weight of the preparation. The amount will vary with the agent chosen and according to whether the preparation is intended to reduce browning to a minimum or to allow browning. The preferred UV-A absorbing agent is 2-hydroxy-4-methoxybenzophenone, alone or in combination with 2,2'-dihydroxy-4-methoxybenzophenone.

Egnede UV-B-absorberende midler innbefatter 4-(dimethyl-amino)-benzoesyreethyles ter, 4-(dimethylamino)-benzoesyre-2 - ethylhexylester ("Escalol 507"), 4-(dimethylamino)-benzoe-syrepentylester ("Escalol 506"), glyceryl-p-aminobenzoat ("Escalol 106"), isobutyl-p-aminobenzoat, ("Cycloform") og isopropyl-p-aminobenzoat. Det eller de UV-B-absorberende midler er tilstede i sluttproduktet i en mengde av fra ca. 1 vekt% til ca. 15 vekt% av preparatet. Mengden vil variere med midlet som velges og med graden av beskyttelse som det ønskes at sluttproduktet skal gi. Det foretrukne UV-B-absorberende middel er 4-(dimethylamino)-benzoesyre-2-ethylhexyl-ester . Suitable UV-B absorbents include 4-(dimethylamino)benzoic acid ethyl ester, 4-(dimethylamino)benzoic acid 2-ethylhexyl ester ("Escalol 507"), 4-(dimethylamino)benzoic acid pentyl ester ("Escalol 506 "), glyceryl p-aminobenzoate ("Escalol 106"), isobutyl p-aminobenzoate, ("Cycloform") and isopropyl p-aminobenzoate. The UV-B absorbing agent or agents are present in the final product in an amount of from approx. 1% by weight to approx. 15% by weight of the preparation. The amount will vary with the agent chosen and with the degree of protection that the final product is desired to provide. The preferred UV-B absorbing agent is 4-(dimethylamino)-benzoic acid 2-ethylhexyl ester.

Preparatet inneholder også fra ca. 50 til ca. 90 vekt%, fortrinnsvis fra ca. 60 til ca. 80 vekt%, vann og fra ca. The preparation also contains from approx. 50 to approx. 90% by weight, preferably from approx. 60 to approx. 80% by weight, water and from approx.

1 til ca. 20 vekt%, fortrinnsvis fra ca. 1 til ca. 10 vekt%, mykgjørende midler, fra ca. 1 til ca. 10 vekt%, fortrinns- 1 to approx. 20% by weight, preferably from approx. 1 to approx. 10% by weight, softeners, from approx. 1 to approx. 10% by weight, preferential

vis fra ca. 1 til ca. 5 vekt%, emulgeringsmidler, fra ca.show from approx. 1 to approx. 5% by weight, emulsifiers, from approx.

0,05 til ca. 2 vekt%, fortrinnsvis fra ca. 0,1 til ca. 1 vekt%, konserveringsmidler og antioxydasjonsmidler og mindre enn ca. 1 vekt% luftstoffer og fargemidler. 0.05 to approx. 2% by weight, preferably from approx. 0.1 to approx. 1% by weight, preservatives and antioxidants and less than approx. 1% by weight air substances and coloring agents.

Egnede mykgjørende midler innbefatter mineralolje, avocadoolje, squalan, octylpalmitat, kakaosmør, sesamolje, vaselin, propylenglycol-dicaprylat-dicaprat, isopropylmyri-stat, osv. Preparatet vil fortrinnsvis inneholde en blanding av flere av disse mykgjørende midler eller andre som er godkjent for kosmetisk bruk. Suitable emollients include mineral oil, avocado oil, squalane, octyl palmitate, cocoa butter, sesame oil, vaseline, propylene glycol dicaprylate dicaprate, isopropyl myristate, etc. The preparation will preferably contain a mixture of several of these emollients or others approved for cosmetic use .

Egnede emulgeringsmidler innbefatter polyethylenglycol-20-sorbitanmonolaurat ("Polysorbat 20"), diethanolamin-cetylfosfat, glycerylstearat, polyethylenglycol-100-stearat, polyethylenglycol-20-stearylkether ("Brij 78", "Steareth 20"), polysorbat 80 ("Tween 80"), osv. Preparatet vil fortrinnsvis inneholde en blanding av to eller flere av disse emulgeringsmidler eller andre som er godkjent for kosmetisk bruk. Suitable emulsifiers include polyethylene glycol-20-sorbitan monolaurate ("Polysorbate 20"), diethanolamine cetyl phosphate, glyceryl stearate, polyethylene glycol-100 stearate, polyethylene glycol-20-stearyl ether ("Brij 78", "Steareth 20"), polysorbate 80 ("Tween 80 "), etc. The preparation will preferably contain a mixture of two or more of these emulsifiers or others that are approved for cosmetic use.

Egnede konserveringsmidler innbefatter imidazolidi-nylurea ("Germall 115"), methylparaben ("Tegosept M"), qua-ternium-15 (N-(3-klora1ly1)-hexaminiumklorid, "Dowcil 200"), propylparaben ("Tegosept P"), dimethyldimethoylhydantoin, benzylalkohol og/eller fenoxyethanol, osv., og det foretrukne antioxydasjonsmiddel utgjøres av en blanding av butylert hyd-roxyanisol, propylenglycol, propylgallat og sitronsyre ("Tenox 2"). Preparatet vil fortrinnsvis inneholde antioxydasjons-middelblandingen og ett eller flere av konserveringsmidlene eller hvilke som helst andre konserveringsmidler og antioxy-das jonsmidler som er godkjent for kosmetisk bruk. Suitable preservatives include imidazolidyl urea ("Germall 115"), methylparaben ("Tegosept M"), quaternium-15 (N-(3-chlora1ly1)-hexaminium chloride, "Dowcil 200"), propylparaben ("Tegosept P") , dimethyldimethoylhydantoin, benzyl alcohol and/or phenoxyethanol, etc., and the preferred antioxidant is a mixture of butylated hydroxyanisole, propylene glycol, propyl gallate and citric acid ("Tenox 2"). The preparation will preferably contain the antioxidant mixture and one or more of the preservatives or any other preservatives and antioxidants that are approved for cosmetic use.

Som ovenfor angitt kan man ved å variere prosentandelen av bestanddeler få preparatet i form av en losjon eller i halvfast form. Ved fremstilling av produktet som en losjon vil man f.eks. tilsette vann i en mengde av fra ca. 60 til 65 vekt% av det ferdige produkt, og ett eller flere fuktemidler, som f.eks. propylenglycol, glycerin, 1,3-butylengly-col, sorbitol, polyethylenglycoler (f.eks. "Carbowax 400"), vil kunne innlemmes i en mengde av inntil ca. 7,5 vekt% av det ferdige produkt. As indicated above, by varying the percentage of ingredients, the preparation can be obtained in the form of a lotion or in semi-solid form. When producing the product as a lotion, one will e.g. add water in an amount of from approx. 60 to 65% by weight of the finished product, and one or more wetting agents, such as e.g. propylene glycol, glycerin, 1,3-butylene glycol, sorbitol, polyethylene glycols (e.g. "Carbowax 400"), can be incorporated in an amount of up to approx. 7.5% by weight of the finished product.

Preparatet ifølge oppfinnelsen vil eventuelt inneholde et fortykningsmiddel i en mengde i området fra ca. 0,05 til ca. 1 vekt%, fortrinnsvis fra ca. 0,05 til ca. 0,3 vekt%. The preparation according to the invention will possibly contain a thickening agent in an amount in the range from approx. 0.05 to approx. 1% by weight, preferably from approx. 0.05 to approx. 0.3% by weight.

Et foretrukket fortykningsmiddel som er egnet for formålet,A preferred thickener suitable for the purpose,

er "Carbopol 940" eller "Carbomer 940", som er hydrofile ac-rylpolymerer tverrbundet med et polyfunksjonelt middel og benyttet sammen med en organisk eller uorganisk base, fortrinnsvis triethanolamin. Andre eksempler på fortykningsmidler som kan benyttes, innbefatter, men er ikke begrenset til, stearinsyre, magnesiumaluminiumsilicat, stearoxydimethicon, hydroxyethylcellulose, hydroxypropylcellulose og xanthangummi. is "Carbopol 940" or "Carbomer 940", which are hydrophilic acrylic polymers cross-linked with a polyfunctional agent and used together with an organic or inorganic base, preferably triethanolamine. Other examples of thickeners that may be used include, but are not limited to, stearic acid, magnesium aluminum silicate, stearoxydimethicone, hydroxyethyl cellulose, hydroxypropyl cellulose, and xanthan gum.

Hudkondisjoneringsmidler som eventuelt kan være tilstede i preparatet ifølge oppfinnelsen, innbefatter allantoin, d- eller dl-panthenol, hydrolysert dyreprotein og lignende. Slike kondisjoneringsmidler kan være tilstede i en mengde Skin conditioning agents which may possibly be present in the preparation according to the invention include allantoin, d- or dl-panthenol, hydrolysed animal protein and the like. Such conditioners may be present in an amount

i området fra ca. 0,01 til ca. 5 vekt%, fortrinnsvis fra ca. in the area from approx. 0.01 to approx. 5% by weight, preferably from approx.

0,05 til ca. 2 vekt%, avhengig av hva hudpreparatet skal bru-kes til. 0.05 to approx. 2% by weight, depending on what the skin preparation is to be used for.

Fremstillingsteknikken vil variere, avhengig av bestanddelene som skal benyttes. I henhold til en foretrukken fremgangsmåte blir fortykningsmiddel, f.eks. sterinsyre, emulgeringsmiddel, f.eks. polysorbat-20-laurat ("Tween 20") og glycerylmonostearat og natriumlaurylsulfat ("Tegacid"spesial ), mykgjørende middel, som f.eks. dimethicon ("Silicon 225"), konserveringsmiddel, som f.eks. propylparaben, og eventuelle solfiltermidler blandet sammen under moderat omrøring for dannelse av en første ikke-vandig blanding. Det dannes også The manufacturing technique will vary, depending on the components to be used. According to a preferred method, thickening agent, e.g. stearic acid, emulsifier, e.g. polysorbate-20 laurate ("Tween 20") and glyceryl monostearate and sodium lauryl sulfate ("Tegacid" special), emollients, such as e.g. dimethicone ("Silicon 225"), preservative, such as propylparaben, and any sunscreen agents mixed together with moderate stirring to form a first non-aqueous mixture. It is also formed

en andre blanding bestående av deionisert vann, gummi-fortykningsmiddel, som f.eks. "Carbopol 490", og om ønsket også andre vannoppløselige bestanddeler, og en tredje blanding bestående av fuktemiddel, f.eks. en polyethylenglycol (f.eks. "Carbowax 400") og konserveringsmiddel, som f.eks. methylparaben og benzylalkohol. Den første, ikke-vandige blanding feie-blandes inn i den andre og den tredje blanding, slik at det dannes en emulsjon. Deretter kan en blanding av en liten mengde deionisert vann og triethanolamin (nøytraliseringsmiddel for "Carbopol 940", om nødvendig) og andre vannoppløselige bestanddeler som kan innlemmes i denne vandige fase, satt til emul-sjonen under omrøring. Vandig sekundært amid tilsettes deretter, og den ferdige blanding avkjøles til romtemperatur, hvoretter den homogeniseres og lagres eller pakkes. a second mixture consisting of deionized water, rubber thickener, such as "Carbopol 490", and if desired also other water-soluble ingredients, and a third mixture consisting of wetting agent, e.g. a polyethylene glycol (eg "Carbowax 400") and preservative, such as methylparaben and benzyl alcohol. The first, non-aqueous mixture is swept into the second and third mixtures to form an emulsion. Then a mixture of a small amount of deionized water and triethanolamine (neutralizing agent for "Carbopol 940", if necessary) and other water-soluble ingredients that can be incorporated into this aqueous phase can be added to the emulsion with stirring. Aqueous secondary amide is then added, and the finished mixture is cooled to room temperature, after which it is homogenized and stored or packaged.

Foretrukne solsperrepreparater ifølge oppfinnelsenPreferred sunscreen preparations according to the invention

som gir maksimal beskyttelse, inneholder fra ca. 60 til ca.which provides maximum protection, contains from approx. 60 to approx.

80 vekt% vann, fra ca. 1 til ca. 10 vekt% av et sekundært amid, som f.eks. N-stearylstearamid, fra ca. 2,5 til ca. 3,5 vekt% UV-A-absorberende midler valgt blant 2-hydroxy-4-methoxy-benzofenon (oxybenzon) og 2,2'-dihydroxy-4-methoxybenzofenon (dioxybenzon), fra ca. 5 til ca. 10 vekt% av det UV-B-absorberende middel 4-(dimethylamino)-benzoesyre-2-ethylhexylester ("Escalol 507"), fra ca. 1 til ca. 5 vekt% fuktemi.dler, fra ca. 1 til ca. 5 vekt% mykgjørende midler, fra ca. 1 til ca. 5 vekt% emulgeringsmidler, fra ca. 0,1 til ca. 0,5 vekt% for tykningsmidler og inntil ca. 1 vekt% totalt av konserveringsmidler, antioxydasjonsmidler og luktstoffer. Mest foretrukket vil det preparat som skal gi maksimal beskyttelse, inneholde ca. 70 vekt% deionisert vann, ca. 4 vekt% N-stearylstearamid, ca. 3 vekt% 2-hydroxy-4-methoxybenzofenon, inntil ca. 1 vekt% 2,2<1->dihydroxy-4-methoxybenzofenon, ca. 8 vekt% 4-(dimethyl-amino)-benzoesyre-2-ethylhexylester, ca. 3 vekt% mykgjørende midler, ca. 5 vekt% emulgeringsmidler, ca. 0,35 vekt% fortykningsmiddel og inntil 1 vekt% totalt av konserveringsmidler, antioxydasjonsmidler og luktstoffer. 80% by weight water, from approx. 1 to approx. 10% by weight of a secondary amide, such as e.g. N-stearyl stearamide, from approx. 2.5 to approx. 3.5% by weight UV-A absorbents chosen from 2-hydroxy-4-methoxy-benzophenone (oxybenzone) and 2,2'-dihydroxy-4-methoxybenzophenone (dioxybenzone), from approx. 5 to approx. 10% by weight of the UV-B absorbing agent 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester ("Escalol 507"), from approx. 1 to approx. 5% by weight of moisture, from approx. 1 to approx. 5% by weight of softening agents, from approx. 1 to approx. 5% by weight of emulsifiers, from approx. 0.1 to approx. 0.5% by weight for thickeners and up to approx. 1% by weight in total of preservatives, antioxidants and fragrances. Most preferably, the preparation that will provide maximum protection will contain approx. 70% by weight deionized water, approx. 4% by weight of N-stearyl stearamide, approx. 3% by weight 2-hydroxy-4-methoxybenzophenone, up to approx. 1% by weight 2,2<1->dihydroxy-4-methoxybenzophenone, approx. 8% by weight 4-(dimethyl-amino)-benzoic acid-2-ethylhexyl ester, approx. 3% by weight of softening agents, approx. 5% by weight emulsifiers, approx. 0.35% by weight of thickener and up to 1% by weight in total of preservatives, antioxidants and fragrances.

Foretrukne solfilterpreparater ifølge oppfinnelsen,Preferred solar filter preparations according to the invention,

som gir beskyttelse, men som likevel muliggjør gradvis bruning, inneholder fra ca. 55 til ca. 65 vekt% vann, fra ca. 1 til ca. 10 vekt% sekundært amid, inntil ca. 1 vekt% 2-hyd-roxy-4-methoxybenzofenon (oxybenzon), fra ca. 3 til 5 vekt% 4-(dimethylamino)-benzoesyre-2-ethylhexylester ("Escalol 507" ) , inntil ca. 7,5 vekt% fuktemidler, fra ca. 1 til ca. 10 vekt% mykgjørende midler, fra ca. 1 til 5 vekt% emulgeringsmidler og inntil ca. 1 vekt% totalt av konserveringsmidler, antioxy-das jonsmidler og luktstoffer og inntil ca. 1 vekt% fortykningsmidler. which provides protection, but which nevertheless enables gradual tanning, contains from approx. 55 to approx. 65% water by weight, from approx. 1 to approx. 10% by weight secondary amide, up to approx. 1% by weight 2-hydroxy-4-methoxybenzophenone (oxybenzone), from approx. 3 to 5% by weight 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester ("Escalol 507"), up to approx. 7.5% by weight humectants, from approx. 1 to approx. 10% by weight of softening agents, from approx. 1 to 5% by weight emulsifiers and up to approx. 1% by weight in total of preservatives, antioxidants and odorants and up to approx. 1% by weight of thickeners.

Det mest foretrukne solfilterpreparat som gir bruning, er en losjon som inneholder fra ca. 70 til ca. 72 vekt% deionisert vann, ca. 4 vekt% av et sekundært amid, ca. 0,5 vekt% 2-hydroxy-4-methoxybenzofenon, ca. 4 vekt% 4-(dimethylami-no ) -benzoesyre-2-ethylhexylester, ca. 3 vekt% glycerin eller propylenglycol, fra ca. 3 til ca. 8 vekt% mykgjørende midler, fra ca. 2 til ca. 5 vekt% emulgeringsmidler, inntil ca. 1 vekt% totalt av konserveringsmidler, antioxydasjonsmidler og luktstoffer og ca. 0,5% fortykningsmiddel. The most preferred sun filter preparation that provides tanning is a lotion that contains from approx. 70 to approx. 72% by weight deionized water, approx. 4% by weight of a secondary amide, approx. 0.5% by weight 2-hydroxy-4-methoxybenzophenone, approx. 4% by weight 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, approx. 3% by weight of glycerin or propylene glycol, from approx. 3 to approx. 8% by weight of softening agents, from approx. 2 to approx. 5% by weight of emulsifiers, up to approx. 1% by weight in total of preservatives, antioxidants and fragrances and approx. 0.5% thickener.

Foretrukne fuktighetspreparater vil ligne de ovenfor beskrevne solfilter- og solsperrepreparater, men de vil ikke inneholde solfiltermidlene. Preferred moisturizing compositions will be similar to the sunscreen and sunscreen compositions described above, but they will not contain the sunscreen agents.

De følgende eksempler illustrerer foreturkne utførel-sesformer av oppfinnelsen. Med mindre annet er angitt, er alle temperaturer uttrykt i grader Celcius. The following examples illustrate preferred embodiments of the invention. Unless otherwise stated, all temperatures are expressed in degrees Celsius.

Eksempel 1Example 1

Et solf ilterprepa-rat med forbedret substantivitet, med følgende sammensetning, fremstilles som beskrevet nedenfor. A solf filter preparation with improved substantivity, with the following composition, is prepared as described below.

Bestanddelene av Fase A blandes imtimt med hverandre The components of Phase A are intimately mixed with each other

i 15 minutter. Deretter blir en blanding av bestanddelene av Fase B feieblandet inn i Fase A. En blanding av bestanddelene av Fase C, oppvarmet ved 80°C, settes så til den oven-stående blanding under hurtig omrøring for å danne en emulsjon. Blandingen kombineres så med Fase D under omrøring, hvoretter Fase E tilsettes og blandingen avkjøles til 30°C, hvorved man får solfilterkrembasispreparatet. for 15 minutes. Then a mixture of the components of Phase B is swept into Phase A. A mixture of the components of Phase C, heated at 80°C, is then added to the above mixture with rapid stirring to form an emulsion. The mixture is then combined with Phase D while stirring, after which Phase E is added and the mixture is cooled to 30°C, whereby the sunscreen cream base preparation is obtained.

Deretter oppvarmes blandingen av N-stearylstearamidThe mixture of N-stearyl stearamide is then heated

og vann ved 100°C, og en tredjedel av solfilterbasispreparatet blandes med denne ved 100°C i 10 minutter. Deretter innblandes den gjenværende del av solfilterbasispreparatet ved 60°C i 15 minutter. Porsjonen avkjøles og homogeniseres for hånd, hvorved man får solfilterpreparatet ifølge oppfinnelsen med forbedret substantivitet. and water at 100°C, and one third of the solar filter base preparation is mixed with this at 100°C for 10 minutes. The remaining part of the solar filter base preparation is then mixed in at 60°C for 15 minutes. The portion is cooled and homogenized by hand, whereby the solar filter preparation according to the invention with improved substantivity is obtained.

Eksempel 2Example 2

Et vannresistent solsperrepreparatat (i form av en emulsjon av olje-i-vann-typen i tykk losjonsform) ifølge oppfinnelsen, med en solbeskyttelsesfaktor (SPF = Sun Protection Factor) på 15 og med den følgende sammensetning ble fremstilt som beskrevet nedenfor. A water-resistant sunscreen preparation (in the form of an emulsion of the oil-in-water type in thick lotion form) according to the invention, with a sun protection factor (SPF = Sun Protection Factor) of 15 and with the following composition was prepared as described below.

SPF-tallet bestemmes ved at man dividerer den minste erythemadose (MED) for beskyttet hud etter påføring av 2 mg/cm<2>av preparatet med MED for ubeskyttet hud. The SPF number is determined by dividing the smallest erythema dose (MED) for protected skin after application of 2 mg/cm<2> of the preparation by the MED for unprotected skin.

Vandig blanding II fremstilles ved at acrylåtpolymeren dispergeres i det deioniserte vann. Blanding III (fremstilt ved enkel blanding av bestanddelene) blandes så med Blanding II. Den kombinerte Blanding II-III oppvarmes så til 75°C. Aqueous mixture II is prepared by dispersing the acrylate polymer in the deionized water. Mixture III (made by simple mixing of the ingredients) is then mixed with Mixture II. The combined Mixture II-III is then heated to 75°C.

Blanding I dannes ved enkel blanding av bestanddelene i et separat kar under oppvarming til 75°C. Mixture I is formed by simply mixing the ingredients in a separate vessel while heating to 75°C.

Blanding I (oppvarmet ved 75°C) settes så til den kombinerte Blanding II-III (likeledes ved 75°C) under feieblanding. Mixture I (heated at 75°C) is then added to the combined Mixture II-III (also at 75°C) under sweeping mixing.

Den kombinerte blanding I-II-III oppvarmes ved 75°CThe combined mixture I-II-III is heated at 75°C

i 30 minutter og tillates å avkjøles i luft til 60°C, hvoretter Blanding IV (fremstilt ved enkel blanding av bestanddelene) tilsettes under feieblanding. Den resulterende porsjon tillates så å avkjøles i luft til 30°C, hvorved man får sol-sperrepreparatet ifølge oppfinnelsen. for 30 minutes and allowed to cool in air to 60°C, after which Mixture IV (prepared by simple mixing of the ingredients) is added under sweep mixing. The resulting portion is then allowed to cool in air to 30°C, whereby the sunscreen preparation according to the invention is obtained.

Eksempel 3Example 3

Et solfilterpreparat ifølge oppfinnelsen, med den føl-gende sammensetning og med en solbeskyttelsesfaktor (SPF) A sun filter preparation according to the invention, with the following composition and with a sun protection factor (SPF)

på 8, fremstilles som beskrevet nedenfor.of 8, is prepared as described below.

Bestanddelene er oppført på vektdelbasis, og kjemika-lienes betegnelse, CTFA og/eller varebetegnelse er angitt. Dette preparat utgjøres av en emulsjon av olje-i-vann-typen The ingredients are listed on a parts-by-weight basis, and the chemical's name, CTFA and/or product name are indicated. This preparation consists of an emulsion of the oil-in-water type

i form av en tykk losjon. in the form of a thick lotion.

Vandig Blanding IA fremstilles ved at acrylatpolymeren dispergeres i det deioniserte vann. Blanding IB (fremstilt ved enkel blanding av bestanddelene) blandes så med Blanding IA. Den kombinerte Blanding IA-B oppvarmes deretter til 75°C. Aqueous Mixture IA is prepared by dispersing the acrylate polymer in deionized water. Mixture IB (prepared by simple mixing of the ingredients) is then mixed with Mixture IA. The combined Mixture IA-B is then heated to 75°C.

Blanding II dannes ved enkel blanding av bestanddelene i et separat kar under oppvarmning ved 75°C. Mixture II is formed by simple mixing of the components in a separate vessel while heating at 75°C.

Blanding II (oppvarmet ved 75°C) settes så til den kombinerte blanding IA-B (likeledes ved 75°C) under feieblanding. Mixture II (heated at 75°C) is then added to the combined mixture IA-B (also at 75°C) with sweep mixing.

Den kombinerte blanding IA-B-II oppvarmes ved 75°CThe combined mixture IA-B-II is heated at 75°C

i 30 minutter og tillates å avkjøles i luft til 60°C, hvoretter blandinger III og IV (hver fremstilt ved enkel blanding) tilsettes, sammen med parfymeoljen, under feieblanding. for 30 minutes and allowed to cool in air to 60°C, after which mixtures III and IV (each prepared by simple mixing) are added, together with the perfume oil, with sweep mixing.

Den resulterende porsjon tillates så å avkjøles til 30°C, hvorved man får solfilterpreparatet ifølge oppfinnelsen. The resulting portion is then allowed to cool to 30°C, whereby the solar filter preparation according to the invention is obtained.

Eksempel 4Example 4

Et solfilterpreparat med en solbeskyttelsesfaktor påA sun filter preparation with a sun protection factor on it

4 og med den følgende sammensetning fremstilles som beskrevet nedenfor. Bestanddelene er oppført på vektdelbasis, og såvel CFTA og varenavn er angitt. Dette preparat utgjøres av en emulsjon av olje-i-vann-typen og har konsistens som en losjon. 4 and with the following composition is prepared as described below. The ingredients are listed on a parts by weight basis, and both the CFTA and product name are indicated. This preparation consists of an emulsion of the oil-in-water type and has the consistency of a lotion.

Vandig Blanding IA fremstilles ved dispergering av acrylatpolymeren i det deioniserte vann. Blanding IB (fremstilt ved enkel blanding av bestandelene) blandes så med Blanding IA. Den kombinerte Blanding IA-B oppvarmes så til 75°C. Aqueous Mixture IA is prepared by dispersing the acrylate polymer in deionized water. Mixture IB (prepared by simple mixing of the ingredients) is then mixed with Mixture IA. The combined Mixture IA-B is then heated to 75°C.

Blanding II (oppvarmet ved 75°C) settes så til den kombinerte Blanding IA-B (likeledes ved 75°C) under feieblanding. Mixture II (heated at 75°C) is then added to the combined Mixture IA-B (also at 75°C) under sweep mixing.

i 30 minutter og tillates å avkjøles til 60°C, hvoretter Blanding III (fremstilt ved enkel blanding) tilsettes under feieblanding. for 30 minutes and allowed to cool to 60°C, after which Mixture III (prepared by simple mixing) is added under sweep mixing.

Den resulterende porsjon tillates deretter å avkjøles til 30°C, hvorved man får solfilterpreparatet ifølge oppfinnelsen . The resulting portion is then allowed to cool to 30°C, whereby the solar filter preparation according to the invention is obtained.

Eksempel 5Example 5

Et fuktighetspreparat med den følgende sammensetning fremstilles som nedenfor beskrevet. Bestanddelene er oppført på vektdelbasis, og såvel CTFA som varebetegnelse er angitt. Preparatet utgjøres av en emulsjon av olje-i-vann-typen og har form av en losjon. A moisturizing preparation with the following composition is prepared as described below. The ingredients are listed on a parts by weight basis, and both the CTFA and product name are indicated. The preparation consists of an emulsion of the oil-in-water type and has the form of a lotion.

Den vandige Blanding IA fremstilles ved blanding av bestanddelene i det deioniserte vann. Blanding II (fremstilt ved enkel blanding av bestanddelene) blandes så med Blanding I. De sammenslåtte Blandinger I-II oppvarmes deretter til 75°C. The aqueous mixture IA is prepared by mixing the components in the deionized water. Mixture II (prepared by simple mixing of the ingredients) is then mixed with Mixture I. The combined Mixtures I-II are then heated to 75°C.

Blanding III dannes ved enkel blanding av bestanddelene i et separat kar under oppvarmning ved 75°C. Mixture III is formed by simple mixing of the components in a separate vessel while heating at 75°C.

Blanding III (oppvarmet ved 75°C) settes så til den kombinerte Blanding I-II-III (likeledes ved 75°C) under feieblanding. Mixture III (heated at 75°C) is then added to the combined Mixture I-II-III (also at 75°C) under sweeping mixing.

i 30 minutter og tillates å avkjøles i luft til 60°C, hvoretter Bestanddel IV tilsettes under feieblanding. for 30 minutes and allowed to cool in air to 60°C, after which Component IV is added with sweeping mixing.

Den resulterende porsjon tillates deretter å avkjøles i luft til 30°C, hvorved man får fuktighetspreparatet ifølge oppfinnelsen. The resulting portion is then allowed to cool in air to 30°C, whereby the moisturizing preparation according to the invention is obtained.

Industriell anvendelighetIndustrial applicability

Preparatene ifølge oppfinnelsen er anvendelige i hudbehandlingspreparater, spesielt som fuktighetspreparater og solfilter- og solsperrepreparater. The preparations according to the invention are applicable in skin treatment preparations, especially as moisturizing preparations and sun filter and sunscreen preparations.

1. I henhold til den foreliggende oppfinnelse tilveiebrin-ges et fuktighetsresistent hudbehandlingspreparat i form av et solfilterpreparat eller fuktighetspreparat, i form av en olje-i-vann-emulsjon eller en vann-i-olje-emulsjon,karakterisert vedat det består i det vesentlige av fra ca. 50 til 90 vekt% vann, fra ca. 1 til ca. 10 vekt% emulgeringsmiddel, et konserveringsmiddel og et sekundært amid med strukturen: 1. According to the present invention, a moisture-resistant skin treatment preparation is provided in the form of a sun filter preparation or moisturizing preparation, in the form of an oil-in-water emulsion or a water-in-oil emulsion, characterized in that it essentially consists of from approx. 50 to 90% by weight water, from approx. 1 to approx. 10% by weight emulsifier, a preservative and a secondary amide with the structure:

hvor og R2er like eller ulike og betegner mettede eller umettede fettsyrerester inneholdende 8-36 carbonatomer og 0-3 dobbeltbindinger samt 0-1 hydroxylgruppe, i en mengde i området fra ca. 0,5 til 10 vekt%, beregnet på det totale preparat, for å bibringe preparatet fuktighetsresistens. where and R2 are the same or different and denote saturated or unsaturated fatty acid residues containing 8-36 carbon atoms and 0-3 double bonds as well as 0-1 hydroxyl group, in an amount in the range from approx. 0.5 to 10% by weight, calculated on the total preparation, to give the preparation moisture resistance.

2. Preparat ifølge krav 1,2. Preparation according to claim 1,

karakterisert vedat R^ og/eller R^inneholder fra ca. 12 til ca. 22 carbonatomer. characterized in that R^ and/or R^ contains from approx. 12 to approx. 22 carbon atoms.

3. Preparat ifølge krav 1,3. Preparation according to claim 1,

karakterisert vedat det sekundære amid er N-stearylstearamid, N-stearylerucamid, N-erucylerucamid, N-oleylpalmitamid, N-stearyloleamid, N-erucylstearamid, N-oleyloleamid, N-palmitylpalmitamid, N-behenylbehenamid, N-behenylerucamid, N-oleylstearamid, N-oleylbehenamid, N-erucylbehenamid eller N-stearyl-hydroxystearamid. characterized in that the secondary amide is N-stearylstearamide, N-stearylerucamide, N-erucylerucamide, N-oleylpalmitamide, N-stearyloleamide, N-erucylstearamide, N-oleyloleamide, N-palmitylpalmitamide, N-behenylbehenamide, N-behenylerucamide, N-oleylstearamide, N-oleylbehenamide, N-erucylbehenamide or N-stearyl-hydroxystearamide.

4 . Preparat ifølge krav 1,4. Preparation according to claim 1,

karakterisert vedat det sekundære amid er N-stearylstearamid. 5. Preparat ifølge krav 1, i form av et fuktighetsresistent solfilterpreparat inneholdende fra ca. 1 til ca. 15 vekt% av minst ett UV-absorberende middel. characterized in that the secondary amide is N-stearyl stearamide. 5. Preparation according to claim 1, in the form of a moisture-resistant solar filter preparation containing from approx. 1 to approx. 15% by weight of at least one UV absorbing agent.

6. Preparat ifølge krav 1,6. Preparation according to claim 1,

karakterisert vedat de UV-absorberende midler innbefatter ett eller flere UV-A-absorberende midler og ett eller flere UV-B-absorberende midler. characterized in that the UV-absorbing agents include one or more UV-A absorbing agents and one or more UV-B absorbing agents.

7. Preparat ifølge krav 6,7. Preparation according to claim 6,

karakterisert vedat det eller de UV-A-absorberende midler er tilstede i en mengde av fra ca. 0,5 til 10 vekt% og det eller de UV-B-absorberende midler er tilstede i en mengde av fra ca. 3 til ca. 10 vekti. characterized in that the UV-A absorbing agent or agents are present in an amount of from approx. 0.5 to 10% by weight and the UV-B absorbing agent(s) are present in an amount of from approx. 3 to approx. 10 by weight.

8. Preparat ifølge krav 7,8. Preparation according to claim 7,

karakterisert vedat det UV-A-absorberende middel utgjøres av ett eller flere forbindelser valgt fra gruppen bestående av 2-(2'-hydroxy-5<1->methylfenyl)-benzotria-zol, 2-(2<1->hydroxy-5'-t-octylfenyl)-benzotriazol, 2,4-dihydroxybenzofenon, 2-hydroxy-4-methoxybenzofenon, 2,2'-4,4<1->tet-rahydroxybenzofenon, 2,2'-dihydroxy-4,4'-dimethoxybenzofenon, 2,2'-dihydroxy-4-methoxybenzofenon, 2-ethylhexyl-4-fenylbenzo-fenoncarbonat, 2-hydroxy-4-methoxy-4'-methylbenzofenon, 2-hyd-roxy-4-(n-octyloxy)-benzofenon, 4-fenylbenzofenon og 2-ethyl-hexyl-2-cyano-3,3'-difenylacrylat, og at det UV-B-absorberende middel utgjøres av én eller flere forbindelser valgt fra gruppen bestående av 4-(dimethylamino)-benzoesyreethylester, 4-(dimethylamino)-benzoesyre-2-ethylhexylester, 4-(dimethyl-amino ) -benzoeyre , amylester, glyceryl-p-aminobaenzoat, isobutyl-p-aminobenzoat og isopropyl-p-aminobenzoat. characterized in that the UV-A absorbing agent consists of one or more compounds selected from the group consisting of 2-(2'-hydroxy-5<1->methylphenyl)-benzotriazole, 2-(2<1->hydroxy- 5'-t-octylphenyl)-benzotriazole, 2,4-dihydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2,2'-4,4<1->tetrahydroxybenzophenone, 2,2'-dihydroxy-4,4 '-dimethoxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2-ethylhexyl-4-phenylbenzophenone carbonate, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-(n-octyloxy )-benzophenone, 4-phenylbenzophenone and 2-ethyl-hexyl-2-cyano-3,3'-diphenylacrylate, and that the UV-B absorbing agent consists of one or more compounds selected from the group consisting of 4-(dimethylamino) -benzoic acid ethyl ester, 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, 4-(dimethyl-amino)-benzoeyre, amyl ester, glyceryl-p-aminobenzoate, isobutyl-p-aminobenzoate and isopropyl-p-aminobenzoate.

9. Preparat ifølge krav 7,9. Preparation according to claim 7,

karakterisert vedat det UV-A-absorberende middel utgjøres av 2-hydroxy-4-methoxybenzofenon alene eller i kombinasjon med 2,2<1->dihydroxy-4-methoxybenzofenon, og at characterized in that the UV-A absorbing agent consists of 2-hydroxy-4-methoxybenzophenone alone or in combination with 2,2<1->dihydroxy-4-methoxybenzophenone, and that

det UV-B-absorberende middel utgjøres av 4-(dimethylamino)-benzoesyre-2-ethylhexylester. the UV-B absorbing agent consists of 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester.

10. Preparat ifølge krav 1,10. Preparation according to claim 1,

karakterisert vedat vann er tilstede i en mengde av fra ca. 50 til 90 vekt%, at mykgjørende midler er tilstede i en mengde av fra ca. 1 til ca. 10 vekt%, at emulgeringsmidler er tilstede i en mengde av fra ca. 1 til ca. 5 vekt%, at fortykningsmidler er tilstede i en mengde av fra ca. 0,1 til ca. 1 vekti, at fuktemidler er tilstede i en mengde av fra ca. 1 til ca. 5 vekt%, og at konserveringsmidler er tilstede i en mengde av fra ca. 0,5 til ca. 1 vekt%. characterized in that water is present in an amount of from approx. 50 to 90% by weight, that softening agents are present in an amount of from approx. 1 to approx. 10% by weight, that emulsifiers are present in an amount of from approx. 1 to approx. 5% by weight, that thickeners are present in an amount of from approx. 0.1 to approx. 1 by weight, that wetting agents are present in an amount of from approx. 1 to approx. 5% by weight, and that preservatives are present in an amount of from approx. 0.5 to approx. 1% by weight.

11. Preparat ifølge krav 5, som gir maksimal UV-beskyttelse og fuktighetsresistens, karakterisert vedat det inneholder fra ca. 60 til ca. 80 vekt% vann, fra ca. 2 til ca. 7 vekti sekundært amid, fra ca. 1 til ca. 5 vekti 2-hydroxy-4-methoxybenzofenon alene eller i kombinasjon med 2,2'-dihydroxy-4-methoxybenzo-fenon, fra ca. 5 til ca. 10 vekti 4-(dimethylamino)-benzoe-syre-2 -ethylhexylester , fra ca. 1 til ca. 10 vekti mykgjørende midler, fra ca. 1 til ca. 5 vekti emulgeringsmidler og inntil ca. 1 vekti totalt av konserveringsmidler, antioxydasjonsmidler og luktstoffer. 11. Preparation according to claim 5, which provides maximum UV protection and moisture resistance, characterized in that it contains from approx. 60 to approx. 80% by weight water, from approx. 2 to approx. 7 wt in secondary amide, from approx. 1 to approx. 5 weight in 2-hydroxy-4-methoxybenzophenone alone or in combination with 2,2'-dihydroxy-4-methoxybenzo-phenone, from approx. 5 to approx. 10 by weight of 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, from approx. 1 to approx. 10 by weight of softening agents, from approx. 1 to approx. 5 by weight of emulsifiers and up to approx. 1 weight in total of preservatives, antioxidants and fragrances.

12. Preparat ifølge krav 11,12. Preparation according to claim 11,

karakterisert vedat det inneholder ca. 73 vekti deionisert vann, ca. 4 vekti N-stearylstearamid, fra ca. 2 til ca. 4 vekti 2-hydroxy-4-methoxy-benzofenon, inntil ca. 1 vekti 2,2'-dihydroxy-4-methoxybenzofenon, ca. 8 vekti 4-(dimethylamino)-benzoesyre-2-ethylhexylester, fra ca. 3 characterized in that it contains approx. 73 weight in deionized water, approx. 4 wt in N-stearyl stearamide, from approx. 2 to approx. 4 weight in 2-hydroxy-4-methoxy-benzophenone, up to approx. 1 weight of 2,2'-dihydroxy-4-methoxybenzophenone, approx. 8 by weight of 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, from approx. 3

til ca. 8 vekti mykgjørende midler, fra ca. 2 til ca. 4 vekti emulgeringsmidler og inntil ca. 1 vekti totalt av konserveringsmidler, antioxydasjonsmidler og luktstoffer. to approx. 8 weight in softening agents, from approx. 2 to approx. 4 by weight of emulsifiers and up to approx. 1 weight in total of preservatives, antioxidants and fragrances.

13. Preparat ifølge krav 1,13. Preparation according to claim 1,

karakterisert vedat det ytterligere innehol- characterized in that it further contains

der et fortykningsmiddel i en mengde i området fra ca. 0,05 til ca. 1 vekt%. 14. I henhold til den foreliggende oppfinnelse tilveiebrin-ges det videre en fremgangsmåte for å forbedre fuktighetsre-sistensegenskapene av et solfilterpreparat som inneholder ett eller flere UV-absorberende midler, where a thickening agent in an amount in the range from approx. 0.05 to approx. 1% by weight. 14. According to the present invention, a method is further provided for improving the moisture resistance properties of a solar filter preparation containing one or more UV absorbing agents,

karakterisert vedat man innlemmer minst 0,5 vekt% av et sekundært amid med strukturen characterized by incorporating at least 0.5% by weight of a secondary amide with the structure

0 0

il ill

R?-C-NHR?-C-NH

<R>l<R>l

hvor og R2er like eller ulike og betegner mettede eller umettede fettsyrerester inneholdende 8-36 carbonatomer og 0-3 dobbeltbindinger samt 0-1 hydroxylgruppe. 15. Fremgangsmåte ifølge krav 14, where and R2 are the same or different and denote saturated or unsaturated fatty acid residues containing 8-36 carbon atoms and 0-3 double bonds and 0-1 hydroxyl group. 15. Method according to claim 14,

karakterisert vedat solfilterpreparatet inneholder fra ca. 3 til ca. 15 vekt% UV-absorberende midler, og at det sekundære amid innlemmes i en mengde av fra ca. characterized in that the solar filter preparation contains from approx. 3 to approx. 15% by weight of UV absorbing agents, and that the secondary amide is incorporated in an amount of from approx.

0,5 til ca. 10 vekti, beregnet på preparatet.0.5 to approx. 10 by weight, calculated for the preparation.

16. Fremgangsmåte ifølge krav 14,karakterisert vedat det sekundære amid er N-stearylstearamid, N-stearylerucamid, N-erucylerucamid, N-oleylpalmitamid, N-stearyloleamid, N-erucylstearamid, N-oleyloleamid, N-palmitylpalmitamid, N-behenylbehenamid, N-behenylerucamid, N-oleylstearamid, N-oleylbehenamid, N-erucylbehenamid eller N-stearylhydroxystearamid. 17. Fremgangsmåte ifølge krav 16, 16. Method according to claim 14, characterized in that the secondary amide is N-stearylstearamide, N-stearylerucamide, N-erucylerucamide, N-oleylpalmitamide, N-stearyloleamide, N-erucylstearamide, N-oleyloleamide, N-palmitylpalmitamide, N-behenylbehenamide, N -behenylerucamide, N-oleylstearamide, N-oleylbehenamide, N-erucylbehenamide or N-stearylhydroxystearamide. 17. Method according to claim 16,

karakterisert vedat det sekundære amid er N-stearylstearamid. characterized in that the secondary amide is N-stearyl stearamide.

18. Preparat ifølge krav 1,18. Preparation according to claim 1,

karakterisert vedat det ytterligere inneholder et fortykningsmiddel i en mengde i området fra ca. 0,05 til ca. 1 vekti. characterized in that it further contains a thickening agent in an amount in the range from approx. 0.05 to approx. 1 weight.

Claims

1. Moisture-resistant skin treatment preparation in the form of a sun filter preparation or moisturizing preparation, in the form of an oil-in-water emulsion or a water-in-oil emulsion, characterized in that it essentially consists of from approx. 50 to 90% by weight water, from approx. 1 to approx. 10% by weight emulsifier, a preservative and a secondary amide with the structure:

where and R^ are the same or different and denote saturated or unsaturated fatty acid residues containing 8-36 carbon atoms and 0-3 double bonds as well as 0-1 hydroxyl group, in an amount in the range from approx. 0.5 to 10% by weight, calculated on the total preparation, to give the preparation moisture resistance.

2. Preparation according to claim 1, characterized in that R 1 and/or R 2 contain from approx. 12 to approx. 22 carbon atoms.

3. Preparation according to claim 1, characterized in that the secondary amide is N-stearylstearamide, N-stearylerucamide, N-erucylerucamide, N-oleylpalmitamide, N-stearyloleamide, N-erucylstearamide, N-oleyloleamide, N-palmitylpalmitamide, N-behenylbehenamide, N-behenylerucamide, N-oleylstearamide , N-oleylbehenamide, N-erucylbehenamide or N-stearyl-hydroxystearamide.

4. Preparation according to claim 1, characterized in that the secondary amide is N-s thearyl stearamide.

5. Preparation according to claim 1, in the form of a moisture-resistant solar filter preparation containing from approx. 1 to approx. 15% by weight of at least one UV absorbing agent.

6. Preparation according to claim 1, characterized in that the UV-absorbing agents include one or more UV-A absorbing agents and one or more UV-B absorbing agents.

7. Preparation according to claim 6, characterized in that the UV-A absorbing agent or agents are present in an amount of from approx. 0.5 to 10% by weight and the UV-B absorbing agent(s) are present in an amount of from approx. 3 to approx. 10% by weight.

8. Preparation according to claim 7, characterized in that the UV-A absorbing agent consists of one or more compounds selected from the group consisting of 2-(2 <1-> hydroxy-5 <1-> methylphenyl)-benzotriazole, 2-(2 <1- > hydroxy-5 <1-> t-octylphenyl)-benzotriazole, 2,4-dihydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2,2 <1-> 4,4 <1-> tetrahydroxybenzophenone, 2,2 '-dihydroxy-4,4 <1-> dimethoxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2-ethylhexyl-4-phenylbenzo-phenone carbonate, 2-hydroxy-4-methoxy-4 <1-> methylbenzophenone, 2 -hydroxy-4-(n-octyloxy)-benzophenone, 4-phenylbenzophenone and 2-ethyl-hexyl-2-cyano-3,3 <1-> diphenylacrylate, and that the UV-B absorbing agent consists of one or more compounds selected from the group consisting of 4-(dimethylamino)-benzoic acid ethyl ester, 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, 4-(dimethyl- amino )-benzoeyre , amyl ester, glyceryl-p-aminobenzoate, isobutyl-p-aminobenzoate and isopropyl-p-aminobenzoate.

9. Preparation according to claim 7, characterized in that the UV-A absorbing agent consists of 2-hydroxy-4-methoxybenzophenone alone or in combination with 2,2'-dihydroxy-4-methoxybenzophenone, and that the UV-B absorbing agent consists of 4-(dimethylamino )-benzoic acid-2-ethylhexyl ester.

10. Preparation according to claim 1, characterized in that water is present in an amount of from approx. 50 to 90% by weight, that softening agents are present in an amount of from approx. 1 to approx. 10% by weight, that emulsifiers are present in an amount of from approx. 1 to approx. 5% by weight, that thickeners are present in an amount of from approx. 0.1 to approx. 1% by weight, that wetting agents are present in an amount of from approx. 1 to approx. 5% by weight, and that preservatives are present in an amount of from approx. 0.5 to approx. 1% by weight.

11. Preparation according to claim 5, which provides maximum UV protection and moisture resistance, characterized by the fact that it contains from approx.

60 to approx. 80% by weight water, from approx. 2 to approx. 7% by weight secondary amide, from approx. 1 to approx. 5% by weight 2-hydroxy-4-methoxybenzophenone alone or in combination with 2,2 <1-> dihydroxy-4-methoxybenzo-phenone, from approx. 5 to approx. 10% by weight 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, from approx. 1 to approx. 10% by weight of softening agents, from approx. 1 to approx. 5% by weight of emulsifiers and up to approx. 1% by weight in total of preservatives, antioxidants and fragrances.

12. Preparation according to claim 11, characterized by the fact that it contains approx. 73% by weight deionized water, approx. 4% by weight of N-stearyl stearamide, from approx. 2 to approx. 4% by weight 2-hydroxy-4-methoxy-benzophenone, up to approx. 1% by weight 2,2'-dihydroxy-4-methoxybenzophenone, approx. 8% by weight 4-(dimethylamino)-benzoic acid-2-ethylhexyl ester, from approx. 3 to approx. 8% by weight of softening agents, from approx. 2 to approx. 4% by weight of emulsifiers and up to approx. 1% by weight in total of preservatives, antioxidants and fragrances.

13. Preparation according to claim 1, characterized in that it further contained a thickening agent in an amount in the range from. about. 0.05 to approx. 1% by weight.

14. Method for improving the moisture resistance properties of a solar filter preparation containing one or more UV absorbing agents, characterized by incorporating at least 0.5% by weight of a secondary amide with the structure

where R, and R2 are the same or different and denote saturated or unsaturated fatty acid residues containing 8-36 carbon atoms and 0-3 double bonds and 0-1 hydroxyl group.

15. Method according to claim 14, characterized in that the solar filter preparation contains from approx. 3 to approx. 15% by weight of UV absorbing agents, and that the secondary amide is incorporated in an amount of from approx.

0.5 to approx. 10% by weight, calculated on the preparation.

16. Method according to claim 14, characterized in that the secondary amide is N-stearylstearamide, N-stearylerucamide, N-erucylerucamide, N-oleylpalmitamide, N-stearyloleamide, N-erucylstearamide, N-oleyloleamide, N-palmitylpalmitamide, N-behenylbehenamide, N-behenylerucamide, N-oleylstearamide, N-oleylbehenamide, N-erucylbehenamide or N-stearylhydroxystearamide.

17. Method according to claim 16, characterized in that the secondary amide is N-stearyl stearamide.

18. Preparation according to claim 1, characterized in that it further contains a thickening agent in an amount in the range from approx. 0.05 to approx. 1% by weight.