NO875478L - BANDING, AND MANUFACTURING THEREOF. - Google Patents
BANDING, AND MANUFACTURING THEREOF.Info
- Publication number
- NO875478L NO875478L NO87875478A NO875478A NO875478L NO 875478 L NO875478 L NO 875478L NO 87875478 A NO87875478 A NO 87875478A NO 875478 A NO875478 A NO 875478A NO 875478 L NO875478 L NO 875478L
- Authority
- NO
- Norway
- Prior art keywords
- wound dressing
- carrier material
- bleeding
- water
- soluble binder
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 239000012876 carrier material Substances 0.000 claims description 16
- 230000000740 bleeding effect Effects 0.000 claims description 14
- 229940037003 alum Drugs 0.000 claims description 7
- 239000003112 inhibitor Substances 0.000 claims description 7
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 6
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 6
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 6
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 239000003232 water-soluble binding agent Substances 0.000 claims description 6
- 239000011230 binding agent Substances 0.000 claims description 5
- BUACSMWVFUNQET-UHFFFAOYSA-H dialuminum;trisulfate;hydrate Chemical compound O.[Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O BUACSMWVFUNQET-UHFFFAOYSA-H 0.000 claims description 4
- 230000002401 inhibitory effect Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 229920000297 Rayon Polymers 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
- 239000002964 rayon Substances 0.000 description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
- 230000002439 hemostatic effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 229920003090 carboxymethyl hydroxyethyl cellulose Polymers 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- -1 polypropylenes Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Landscapes
- Package Frames And Binding Bands (AREA)
Description
Foreliggende oppfinnelse vedrører en blødningshemmende sårforbinding i porøs form, som f.eks. kan bestå av vevd eller sydd eller fluffet bærermateriale, vatt eller plasmateriale. Som bærermateriale kan også benyttes bomull, rayon, polyamid, polyester polyolefiner og/eller polypropylener, likeledes skumformige plastre. Oppfinnelssen vedrører også dets frem-stillingsmåte . The present invention relates to a bleeding-inhibiting wound dressing in porous form, which e.g. may consist of woven or sewn or fluffed carrier material, wadding or plastic material. As a carrier material, cotton, rayon, polyamide, polyester polyolefins and/or polypropylenes can also be used, as well as foam plasters. The invention also relates to its manufacturing method.
Man har i lang tid forsøkt å impregnere slike sårforbindinger med blødningshemmende midler, med det har hittil ikke vært mulig å sikre den herfor nødvendige kontrollerbare avgivning av slike virksomme midler og det har ikke i tilstrekkelig grad vært mulig å bevirke midlenes forankring i bærermaterlalet som anvendes i sårforbindingen. Attempts have been made for a long time to impregnate such wound dressings with anti-bleeding agents, but so far it has not been possible to ensure the necessary controllable release of such active agents and it has not been possible to a sufficient extent to effect the anchoring of the agents in the carrier material used in the wound dressing.
Det har nå overraskende vist seg at dette problem kan løses ved at i det minste den del av bærermaterialets overflate som er tenkt å ligge mot såret impregneres med et blødnings-hemmende middel i en mengde på mellom 2 og 20 vekt#, regnet på bærermaterlalet. It has now surprisingly turned out that this problem can be solved by impregnating at least the part of the surface of the carrier material which is intended to lie against the wound with a bleeding-inhibiting agent in an amount of between 2 and 20% by weight, calculated on the carrier material layer.
Ifølge en foretrukket utførelsesform av oppfinnelsen tilsettes det anvendte blødningshemmende middel til bærermaterlalet før et vannløselig bindemiddel tilsettes. According to a preferred embodiment of the invention, the used anti-bleeding agent is added to the carrier material layer before a water-soluble binder is added.
I henhold til oppfinnelsen består de anvendte blødningshem-mende midler av et astringerende stoff, såsom alun, aluminiumsulfat eller andre uorganiske salter, og som egnet bindemiddel anvendes ifølge oppfinnelsen karboksymetylcellulose, hydroksyetylcellulose eller lignende. Det kan også anvendes polyvinylpyrolidoner, polyvinylalkanoler og lignende. According to the invention, the anti-bleeding agents used consist of an astringent substance, such as alum, aluminum sulphate or other inorganic salts, and carboxymethyl cellulose, hydroxyethyl cellulose or the like is used as a suitable binder according to the invention. Polyvinyl pyrrolidones, polyvinyl alkanols and the like can also be used.
Oppfinnelsen omfatter også en fremgangsmåte for fremstilling av sårforbindingen i henhold til foreliggende oppfinnelse, som i hovedsak kjennetegnes ved at et blødningshemmende middel oppløses i et vannløselig bindemiddel, hvoretter den slik erholdte blanding anbringes på et bærermateriale påtenkt som sårforbinding i en slik konsentrasjon at det blødningshemmende midlet utgjør mellom 2 og 20 vekt# regnet på bærermaterlalet. For dette formål anvendes alun eller aluminiumsulfat og karboksymetylcellulose som bindemidler. The invention also includes a method for the production of the wound dressing according to the present invention, which is mainly characterized by the fact that a bleeding inhibitor is dissolved in a water-soluble binder, after which the mixture thus obtained is placed on a carrier material intended as a wound dressing in such a concentration that the bleeding inhibitor amount to between 2 and 20 weight# calculated on the carrier material. For this purpose, alum or aluminum sulphate and carboxymethyl cellulose are used as binders.
Oppfinnelsen skal i det følgende beskrives nærmere under henvisning til nedenstående utførelseseksempel Eksempel 1 In the following, the invention will be described in more detail with reference to the embodiment example below, Example 1
En 2% oppløsning av hydroksyetylcellulose, kjent under navnet "Natrosol" (Herkules Inc.) fremstilles og heri oppløses alun A 2% solution of hydroxyethyl cellulose, known under the name "Natrosol" (Herkules Inc.) is prepared and alum is dissolved in this
- KAI(SO4)2+12H20 - til en konsentrasjon på ca. 10$.- KAI(SO4)2+12H20 - to a concentration of approx. 10$.
Et fiberstoff bestående av rayonfibre (fremstilt på "den tørre måten", dvs. uten bindemiddel) med en flatevekt på A fiber fabric consisting of rayon fibers (produced in the "dry way", i.e. without binder) with a basis weight of
120 g/m^ gjennomfuktes med den ovenfor fremstilte oppløsning i minst 15 sekunder. Deretter komprimeres fiberstoffet, slik at den absorberte mengde av oppløsningen tilsvarer den dobbelte vekt av stoffet før gjennomfukting. Det på denne måte impregnerte bærermateriale tørkes siden ved ca 80°C. 120 g/m² is moistened with the solution prepared above for at least 15 seconds. The fiber fabric is then compressed, so that the absorbed amount of the solution corresponds to twice the weight of the fabric before wetting. The carrier material impregnated in this way is then dried at about 80°C.
Det slik erholdte produkts blødningshemmende virkning ble undersøkt på en blødende svinelever samtidig med en ikke impregnert sårforbinding. Etter sterilisering ble begge sårforbindingene anbrakt på det blødende såret. Ved den ikke impregnerte forbinding kunne en gjennomblødning fastslås og en endelig blodkoagulering oppsto ikke før etter 7,6 minutter, mens man ved forbindingen som var impregnert i henhold til oppfinnelsen erholdt en blodstillende virkning allerede etter 1,8 minutter. The bleeding-inhibiting effect of the product thus obtained was investigated on a bleeding pig liver at the same time as a non-impregnated wound dressing. After sterilization, both wound dressings were applied to the bleeding wound. With the non-impregnated dressing, bleeding could be determined and a final blood coagulation did not occur until after 7.6 minutes, while with the dressing which was impregnated according to the invention, a hemostatic effect was obtained already after 1.8 minutes.
Eksempel 2Example 2
Et rayonmateriale ble impregnert med en 10$ alunoppløsning sammen med 1% CMC (karboksymetylcellulose) samt bindemiddel ved besprøytning, slik at alunmengden gikk opp til ca. 5 vekt$ regnet på bærermaterlalet. Etter påfølgende tørking og A rayon material was impregnated with a 10$ alum solution together with 1% CMC (carboxymethyl cellulose) and binder by spraying, so that the amount of alum went up to approx. 5 weight$ calculated on the carrier material. After subsequent drying and
forsøk som i eksempel 1 kunne en blodstillende effekt oppnås etter 2,1 minutt. experiment as in example 1, a hemostatic effect could be achieved after 2.1 minutes.
Claims (9)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO87875478A NO875478L (en) | 1987-12-29 | 1987-12-29 | BANDING, AND MANUFACTURING THEREOF. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO87875478A NO875478L (en) | 1987-12-29 | 1987-12-29 | BANDING, AND MANUFACTURING THEREOF. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO875478D0 NO875478D0 (en) | 1987-12-29 |
| NO875478L true NO875478L (en) | 1989-06-30 |
Family
ID=19890507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO87875478A NO875478L (en) | 1987-12-29 | 1987-12-29 | BANDING, AND MANUFACTURING THEREOF. |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO875478L (en) |
-
1987
- 1987-12-29 NO NO87875478A patent/NO875478L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO875478D0 (en) | 1987-12-29 |
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