NO870779L - SOLUBILIZATION OF PROTEINS FOR PHARMACEUTICAL PREPARATIONS USING POLYMER CONJUGATION. - Google Patents

SOLUBILIZATION OF PROTEINS FOR PHARMACEUTICAL PREPARATIONS USING POLYMER CONJUGATION.

Info

Publication number
NO870779L
NO870779L NO870779A NO870779A NO870779L NO 870779 L NO870779 L NO 870779L NO 870779 A NO870779 A NO 870779A NO 870779 A NO870779 A NO 870779A NO 870779 L NO870779 L NO 870779L
Authority
NO
Norway
Prior art keywords
solubilization
proteins
pharmaceutical preparations
polymer conjugation
conjugation
Prior art date
Application number
NO870779A
Other languages
Norwegian (no)
Other versions
NO171295C (en
NO171295B (en
NO870779D0 (en
Inventor
Nandini Katre
Michael James Knauf
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1986/001252 external-priority patent/WO1987000056A1/en
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of NO870779L publication Critical patent/NO870779L/en
Publication of NO870779D0 publication Critical patent/NO870779D0/en
Publication of NO171295B publication Critical patent/NO171295B/en
Publication of NO171295C publication Critical patent/NO171295C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A61K47/6819—Plant toxins
    • A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
    • A61K47/6827—Ricin A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO870779A 1985-06-26 1987-02-25 PROCEDURE FOR PREPARING A PHARMACEUTICAL PREPARATION IN THE FORM OF A BIOLOGICALLY ACTIVE CONJUGATED PROTEIN NO171295C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74995585A 1985-06-26 1985-06-26
PCT/US1986/001252 WO1987000056A1 (en) 1985-06-26 1986-06-06 Solubilization of proteins for pharmaceutical compositions using polymer conjugation

Publications (4)

Publication Number Publication Date
NO870779L true NO870779L (en) 1987-02-25
NO870779D0 NO870779D0 (en) 1987-02-25
NO171295B NO171295B (en) 1992-11-16
NO171295C NO171295C (en) 1993-02-24

Family

ID=26773725

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870779A NO171295C (en) 1985-06-26 1987-02-25 PROCEDURE FOR PREPARING A PHARMACEUTICAL PREPARATION IN THE FORM OF A BIOLOGICALLY ACTIVE CONJUGATED PROTEIN

Country Status (2)

Country Link
AU (1) AU580431B2 (en)
NO (1) NO171295C (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1297003C (en) * 1985-09-20 1992-03-10 Jack H. Nunberg Composition and method for treating animals
CA1283046C (en) * 1986-05-29 1991-04-16 Nandini Katre Tumor necrosis factor formulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4414147A (en) * 1981-04-17 1983-11-08 Massachusetts Institute Of Technology Methods of decreasing the hydrophobicity of fibroblast and other interferons
EP0154316B1 (en) * 1984-03-06 1989-09-13 Takeda Chemical Industries, Ltd. Chemically modified lymphokine and production thereof

Also Published As

Publication number Publication date
AU5970086A (en) 1987-01-30
NO171295C (en) 1993-02-24
NO171295B (en) 1992-11-16
NO870779D0 (en) 1987-02-25
AU580431B2 (en) 1989-01-12

Similar Documents

Publication Publication Date Title
DE3586313D1 (en) CONJUGATES OF PHARMACEUTICAL USEFUL PROTEINS.
PH25004A (en) Solubilization of proteins for pharmaceutical compositions using polymer conjugation
DK360988D0 (en) PHARMACEUTICAL CYCLODEXTRIN CONTAINING PREPARATIONS
NO854194L (en) PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS CONTAINING ANTRACYCLING GYCOSIDES.
NO873534L (en) STABLE PHARMACEUTICAL GEL PREPARATION.
DK149988D0 (en) STABLE PHARMACEUTICAL PREPARATIONS
DK163923C (en) 2-PHENYL-3-AMINOMETHYL-IMIDAZOOE1,2-AAAPYRIDINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS
DK413987D0 (en) PHARMACEUTICAL PREPARATIONS
DK259186A (en) NATIONAL PHARMACEUTICAL PREPARATIONS
NO872551D0 (en) PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS
DK652787A (en) PHARMACEUTICAL PREPARATIONS
DE3682960D1 (en) PHARMACEUTICAL PREPARATIONS.
NO862439L (en) PHARMACEUTICAL PREPARATIONS.
DK111686D0 (en) SUSTAINABLE PHARMACEUTICAL PREPARATIONS
NO874193D0 (en) PHARMACEUTICAL PREPARATIONS.
DK52086A (en) PHARMACEUTICAL PREPARATIONS CONTAINING ERGOTAL KALOIDS
NO874200D0 (en) PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS
DK447887D0 (en) PHARMACEUTICAL PREPARATIONS
DK340388D0 (en) AMINOCYCLOPENTYLETHYLETERS, PREPARING THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS
NO870779L (en) SOLUBILIZATION OF PROTEINS FOR PHARMACEUTICAL PREPARATIONS USING POLYMER CONJUGATION.
NO872233D0 (en) PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS
NO873423D0 (en) PROCEDURE FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS
DE3671630D1 (en) GLYCERO-3 (2) -PHOSPHO-L-SERINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
DK645988A (en) BIPHENYL DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME
DK149588A (en) XYLOMETAZOLE-CONTAINING PHARMACEUTICAL PREPARATIONS

Legal Events

Date Code Title Description
MK1K Patent expired