NO820324L - BAKERY-DRILLING WOUND COMPOUND - Google Patents

Description

This invention relates to a bactericidal wound dressing comprising a absorbent absorbent pad and around this a thin, permeable sleeve.

One of the biggest problems in nursing is to protect

a wound or surgical incision against infection by body-specific or airborne bacteria so that you achieve the fastest and most complication-free healing possible. To overcome this problem, bactericides are used. However, the commonly used bactericidal wound treatment agents have the disadvantage that after a relatively short period of use they give rise to resistant strains.

The purpose of the present invention is to provide a wound dressing which protects the wound against body-specific bacteria penetrating through the dressing without the simultaneous formation of resistant strains.

This is achieved - according to the invention - by using a bactericidal agent which consists of copper, silver or gold in the form of a metal or compound. The reaction of these metals destroys both the bacteria themselves and their building blocks in the form of ribose. This makes it impossible to build up DNA and RNA, which are necessary for bacterial mitosis.

The present invention thus relates to a bactericidal wound dressing which comprises a absorbent absorbent pad and around this a thin permeable sleeve, and the dressing according to the invention is characterized by the fact that the sleeve on one side of the dressing, which must face the wound, consists of one with metallic copper or a copper compound coated, non-absorbent, liquid-permeable material. Metallic copper is preferably used. The copper-coated material can consist of a regular woven or non-woven material of polyester, polyamide, polyurethane, polyethylene, polypropylene or cellulose triacetate or of a perforated film of polyester, polyamide, polyurethane, polyethylene, polypropylene or cellulose acetate butyrate.

The dressing thus comprises a thin, copper-coated material which is permeable to wound secretions, so that this can be absorbed in the underlying absorption material, e.g. bulky cellulose, cotton or rayon wadding. In this way, an exceptional bactericidal protection is achieved. The tendency of the dressing to stick to the wound is significantly reduced if the copper-coated material has no absorption of its own, but consists of a synthetic material. The material must of course not contain or hold toxic, allergenic or pyrogenic substances.

The invention is described in more detail in the following example

and with reference to the attached drawing which shows a section through a bandage according to the invention.

Example

Experiments were carried out with small copper-coated glass beads in a ratio of 1 ml glass beads per 1 ml of soy broth, which was inoculated with 10<10> organisms Staph. aureus per ml broth. After 2-4 hours, the bacteria were completely killed. This is of great interest, since it is precisely these staphylococci that cause sores to form in wounds.

Other in vitro experiments with copper acetate in cultures of Coli, Pseudomonas, Proteus and Klebsiella in a concentration of

6 7 10 -10 organisms per ml broth was performed. It then turned out that total killing of the bacteria was achieved within 2-4 hours at a copper quantity of 150-250 micrograms per ml inoculated soy broth. The required amount of copper depends on the type and strain of bacteria and the number of microorganisms per ml.

The drawing shows a bandage according to the invention, which consists of a thin, impenetrable. material .1 of so-called "spunbonded" polyamide fiber, e.g. Monsanto's "Cerex" with a basis weight of 11 g/m 2 , coated with 300-500 micrograms of copper/cm<2>

on the side of the dressing that should face the wound.

On this copper-coated material there is an absorption pad 2

consisting of. a strongly absorbent material, e.g. fluffed cellulose fiber, cotton or rayon wadding, several layers of cellulose or tissue paper. As dressings are often used over highly oozing wounds, it is advantageous to place a barrier layer 3 above the absorbent pad which prevents wound secretions from penetrating to the upper side of the dressing, but allows moisture to evaporate unimpeded. The barrier layer can consist of a wet-strength "tissue" with a surface weight of approx. 30 g/m 2 , which is impregnated with a liquid-repellent agent. Outside the barrier layer, a strong, water vapor-permeable material 4 is placed, for example a layer of non-woven material, which forms the back side of the dressing.

The edges of the copper-coated material and the back side of the dressing are joined by means of gluing, welding or other known means. The width of both of these materials is kept 20-25 mm greater than the width of the absorbent pad 2. If all the materials included in the dressing are used in the form of running webs, dressings of suitable length can be produced by cutting off directly from the joined webs. The ends of the bandage are thereby left open. If the absorption cushion 2 and the barrier layer 3 are instead inserted between the paths 1 and 4

in the form of fitted pieces with specific spacing, preferably 20-25 mm, transverse sealing of the webs 1 and 4 can take place in the same way as along the sides, and a closed connection on all sides is achieved.

By, among others a. large burns occur in the wound, often partly burnt tissue remains which, if not removed, can cause toxic substances. This can delay the laying. With a bandage according to the invention, it is possible to give the copper-coated surface a thin layer of the protein-degrading enzyme trypsin, which quickly converts tissue residues into harmless amino acids.

Both such a burn dressing and a dressing for highly exuding wounds such as leg wounds can also be given an increased healing effect by coating the wound surface of the dressing with a tissue astringent, which reduces wound secretion. Suitable such astringent agents are organic aluminum salts, such as basic aluminum acetate, aluminum oleate or the addition product of such an aluminum salt with tannin.

Claims (5)

1. Bactericidal wound dressing comprising a absorbent absorbent pad (2) and around this a thin, permeable sleeve (1, 4), characterized in that the sleeve on the side of the dressing that must face the wound consists of one with metallic copper or a copper compound coated, non-absorbent, liquid-permeable material (1). 2. Dressing according to claim 1, characterized in that the copper-coated material consists of an ordinary woven or non-woven material of polyester, polyamide, polyurethane, polyethylene, polypropylene or cellulose triacetate. 3. Dressing according to claim 1, characterized in that the copper-coated material consists of a perforated film of polyester, polyamide, polyurethane, polyethylene, polypropylene or cellulose acetate butyrate. 4. Dressing according to one of claims 1-3, characterized in that the surface of the dressing which, when used, must face the wound, is provided with a protein-degrading enzyme, such as trypsin. 5. Dressing according to one of the claims" 1-4, characterized in that the surface of the dressing which must be facing the wound during use is provided with a tissue astringent agent consisting of a organic aluminum salt, such as basic aluminum acetate, aluminum oleate or an addition product between such an aluminum salt and tannin.