NO744336L - - Google Patents
Info
- Publication number
- NO744336L NO744336L NO744336A NO744336A NO744336L NO 744336 L NO744336 L NO 744336L NO 744336 A NO744336 A NO 744336A NO 744336 A NO744336 A NO 744336A NO 744336 L NO744336 L NO 744336L
- Authority
- NO
- Norway
- Prior art keywords
- volumes
- buffer solution
- stated
- passed
- ion exchanger
- Prior art date
Links
- 150000002500 ions Chemical group 0.000 claims description 45
- 238000000034 method Methods 0.000 claims description 38
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 28
- 239000007853 buffer solution Substances 0.000 claims description 20
- 239000011780 sodium chloride Substances 0.000 claims description 14
- 239000000243 solution Substances 0.000 claims description 13
- 210000002381 plasma Anatomy 0.000 claims description 11
- 102000004169 proteins and genes Human genes 0.000 claims description 9
- 108090000623 proteins and genes Proteins 0.000 claims description 9
- 238000010521 absorption reaction Methods 0.000 claims description 4
- 150000001450 anions Chemical class 0.000 claims description 3
- 238000002798 spectrophotometry method Methods 0.000 claims description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- 230000031700 light absorption Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 108010044467 Isoenzymes Proteins 0.000 description 67
- 102000004420 Creatine Kinase Human genes 0.000 description 41
- 108010042126 Creatine kinase Proteins 0.000 description 41
- 210000002966 serum Anatomy 0.000 description 33
- 208000010125 myocardial infarction Diseases 0.000 description 22
- 102000003855 L-lactate dehydrogenase Human genes 0.000 description 21
- 108700023483 L-lactate dehydrogenases Proteins 0.000 description 21
- 238000010586 diagram Methods 0.000 description 13
- 235000002639 sodium chloride Nutrition 0.000 description 11
- 229960002668 sodium chloride Drugs 0.000 description 10
- 102000004190 Enzymes Human genes 0.000 description 9
- 108090000790 Enzymes Proteins 0.000 description 9
- 210000005013 brain tissue Anatomy 0.000 description 9
- 239000003708 ampul Substances 0.000 description 7
- 239000000872 buffer Substances 0.000 description 7
- 238000005342 ion exchange Methods 0.000 description 7
- 206010061216 Infarction Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000007574 infarction Effects 0.000 description 5
- 238000000926 separation method Methods 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 208000029549 Muscle injury Diseases 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- 210000005003 heart tissue Anatomy 0.000 description 4
- 210000002027 skeletal muscle Anatomy 0.000 description 4
- 238000004587 chromatography analysis Methods 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000001962 electrophoresis Methods 0.000 description 3
- 210000002216 heart Anatomy 0.000 description 3
- 208000006454 hepatitis Diseases 0.000 description 3
- 231100000283 hepatitis Toxicity 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 208000007848 Alcoholism Diseases 0.000 description 2
- 201000002481 Myositis Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 208000003532 hypothyroidism Diseases 0.000 description 2
- 230000002989 hypothyroidism Effects 0.000 description 2
- 239000007927 intramuscular injection Substances 0.000 description 2
- 238000010255 intramuscular injection Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012549 training Methods 0.000 description 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 2
- 208000012260 Accidental injury Diseases 0.000 description 1
- 102000013563 Acid Phosphatase Human genes 0.000 description 1
- 108010051457 Acid Phosphatase Proteins 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010067125 Liver injury Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 229920004482 WACKER® Polymers 0.000 description 1
- -1 anionic ion Chemical class 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 208000029028 brain injury Diseases 0.000 description 1
- 230000003683 cardiac damage Effects 0.000 description 1
- 238000013194 cardioversion Methods 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/007—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isoenzyme profiles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42600273A | 1973-12-19 | 1973-12-19 | |
| US47343874A | 1974-05-28 | 1974-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO744336L true NO744336L (da) | 1975-07-14 |
Family
ID=27026882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO744336A NO744336L (da) | 1973-12-19 | 1974-12-02 |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5093693A (da) |
| CH (1) | CH595634A5 (da) |
| DE (1) | DE2437785A1 (da) |
| FR (1) | FR2255601B1 (da) |
| GB (1) | GB1481463A (da) |
| NO (1) | NO744336L (da) |
| SE (1) | SE7408786L (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2005830B (en) * | 1977-10-11 | 1982-05-26 | American Hospital Supply Corp | Isoenzyme determination |
| US4200691A (en) | 1978-02-15 | 1980-04-29 | E. I. Du Pont De Nemours And Company | Method for isolating MB creatine kinase |
-
1974
- 1974-07-03 SE SE7408786A patent/SE7408786L/xx unknown
- 1974-08-06 DE DE2437785A patent/DE2437785A1/de active Pending
- 1974-08-13 CH CH1105374A patent/CH595634A5/xx not_active IP Right Cessation
- 1974-10-15 GB GB44671/74A patent/GB1481463A/en not_active Expired
- 1974-10-23 JP JP49121526A patent/JPS5093693A/ja active Pending
- 1974-10-24 FR FR7435751A patent/FR2255601B1/fr not_active Expired
- 1974-12-02 NO NO744336A patent/NO744336L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1481463A (en) | 1977-07-27 |
| AU7087174A (en) | 1976-01-08 |
| DE2437785A1 (de) | 1975-06-26 |
| CH595634A5 (da) | 1978-02-15 |
| JPS5093693A (da) | 1975-07-25 |
| FR2255601B1 (da) | 1978-11-24 |
| FR2255601A1 (da) | 1975-07-18 |
| SE7408786L (da) | 1975-06-23 |
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| Mercer | Separation of tissue and serum creatine kinase isoenzymes by ion-exchange column chromatography | |
| Varat et al. | Cardiac specific creatine phosphokinase isoenzyme in the diagnosis of acute myocardial infarction. | |
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