NO323217B1 - Fremgangsmate for rensing av apolipoprotein A eller apolipoprotein E. - Google Patents
Fremgangsmate for rensing av apolipoprotein A eller apolipoprotein E. Download PDFInfo
- Publication number
- NO323217B1 NO323217B1 NO19991208A NO991208A NO323217B1 NO 323217 B1 NO323217 B1 NO 323217B1 NO 19991208 A NO19991208 A NO 19991208A NO 991208 A NO991208 A NO 991208A NO 323217 B1 NO323217 B1 NO 323217B1
- Authority
- NO
- Norway
- Prior art keywords
- surfactant
- apolipoprotein
- range
- polymer material
- aqueous solution
- Prior art date
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- 229920001983 poloxamer Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229940068965 polysorbates Drugs 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009979 protective mechanism Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 230000004141 reverse cholesterol transport Effects 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 description 1
- 239000012064 sodium phosphate buffer Substances 0.000 description 1
- RWVGQQGBQSJDQV-UHFFFAOYSA-M sodium;3-[[4-[(e)-[4-(4-ethoxyanilino)phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]-2-methylcyclohexa-2,5-dien-1-ylidene]methyl]-n-ethyl-3-methylanilino]methyl]benzenesulfonate Chemical compound [Na+].C1=CC(OCC)=CC=C1NC1=CC=C(C(=C2C(=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C)C=2C(=CC(=CC=2)N(CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C)C=C1 RWVGQQGBQSJDQV-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229940035044 sorbitan monolaurate Drugs 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 230000002277 temperature effect Effects 0.000 description 1
- DZLFLBLQUQXARW-UHFFFAOYSA-N tetrabutylammonium Chemical compound CCCC[N+](CCCC)(CCCC)CCCC DZLFLBLQUQXARW-UHFFFAOYSA-N 0.000 description 1
- CBXCPBUEXACCNR-UHFFFAOYSA-N tetraethylammonium Chemical compound CC[N+](CC)(CC)CC CBXCPBUEXACCNR-UHFFFAOYSA-N 0.000 description 1
- QEMXHQIAXOOASZ-UHFFFAOYSA-N tetramethylammonium Chemical compound C[N+](C)(C)C QEMXHQIAXOOASZ-UHFFFAOYSA-N 0.000 description 1
- OSBSFAARYOCBHB-UHFFFAOYSA-N tetrapropylammonium Chemical compound CCC[N+](CCC)(CCC)CCC OSBSFAARYOCBHB-UHFFFAOYSA-N 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- IMFACGCPASFAPR-UHFFFAOYSA-O tributylazanium Chemical compound CCCC[NH+](CCCC)CCCC IMFACGCPASFAPR-UHFFFAOYSA-O 0.000 description 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-O triethylammonium ion Chemical compound CC[NH+](CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-O 0.000 description 1
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 description 1
- YFTHZRPMJXBUME-UHFFFAOYSA-N tripropylamine Chemical compound CCCN(CCC)CCC YFTHZRPMJXBUME-UHFFFAOYSA-N 0.000 description 1
- YHBHQYRDAVETGQ-UHFFFAOYSA-N triton x 100 Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCCCCCCCCCO)C=C1 YHBHQYRDAVETGQ-UHFFFAOYSA-N 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9603304A SE9603304D0 (sv) | 1996-09-11 | 1996-09-11 | Process for purifying a compound |
| US2673996P | 1996-09-26 | 1996-09-26 | |
| PCT/SE1997/001502 WO1998011127A1 (en) | 1996-09-11 | 1997-09-08 | A process for purifying apolipoproteins and a composition for use in the process |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO991208D0 NO991208D0 (no) | 1999-03-11 |
| NO991208L NO991208L (no) | 1999-05-11 |
| NO323217B1 true NO323217B1 (no) | 2007-01-29 |
Family
ID=26662746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19991208A NO323217B1 (no) | 1996-09-11 | 1999-03-11 | Fremgangsmate for rensing av apolipoprotein A eller apolipoprotein E. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0954524B1 (da) |
| JP (1) | JP2001500154A (da) |
| AT (1) | ATE236925T1 (da) |
| AU (1) | AU729536B2 (da) |
| CA (1) | CA2265929A1 (da) |
| DE (1) | DE69720786T2 (da) |
| DK (1) | DK0954524T3 (da) |
| ES (1) | ES2197361T3 (da) |
| NO (1) | NO323217B1 (da) |
| NZ (1) | NZ334589A (da) |
| PT (1) | PT954524E (da) |
| WO (1) | WO1998011127A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7205280B2 (en) * | 1998-03-11 | 2007-04-17 | Cognosci, Inc. | Methods of suppressing microglial activation |
| US6454950B1 (en) | 1998-12-30 | 2002-09-24 | Amersham Pharmacia Biotech Ab | Separation method utilizing liquid-liquid partition |
| SE9904803D0 (sv) * | 1999-12-27 | 1999-12-27 | Amersham Pharm Biotech Ab | Method for the isolation of hydrophobic proteins |
| FR2827192B1 (fr) * | 2001-07-13 | 2004-06-04 | Cognis France Sa | Preparations contenant des agents tensio-actifs non ioniques comme agents d'extraction |
| CN100357325C (zh) * | 2005-10-23 | 2007-12-26 | 王贤理 | 一种抗apoA I、apoB抗体制备方法以及用于检测apoA I、apoB的试剂盒 |
| US9176105B2 (en) | 2010-08-20 | 2015-11-03 | President And Fellows Of Harvard College | Density-based separation of biological analytes using multiphase systems |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229996B (it) * | 1989-04-20 | 1991-09-20 | Cesare Sirtori | Espressione di apolipoproteina ai e apolipoproteina ai-milano in lievito e composizioni farmaceutiche che contengono dette apolipoproteine. |
| WO1993000443A1 (en) * | 1991-06-26 | 1993-01-07 | Bio-Technology General Corp. | Purification of recombinant apolipoprotein e from bacteria |
-
1997
- 1997-09-08 CA CA002265929A patent/CA2265929A1/en not_active Abandoned
- 1997-09-08 DK DK97939315T patent/DK0954524T3/da active
- 1997-09-08 JP JP10513557A patent/JP2001500154A/ja not_active Withdrawn
- 1997-09-08 ES ES97939315T patent/ES2197361T3/es not_active Expired - Lifetime
- 1997-09-08 AT AT97939315T patent/ATE236925T1/de not_active IP Right Cessation
- 1997-09-08 WO PCT/SE1997/001502 patent/WO1998011127A1/en not_active Ceased
- 1997-09-08 AU AU41430/97A patent/AU729536B2/en not_active Ceased
- 1997-09-08 DE DE69720786T patent/DE69720786T2/de not_active Expired - Fee Related
- 1997-09-08 PT PT97939315T patent/PT954524E/pt unknown
- 1997-09-08 NZ NZ334589A patent/NZ334589A/xx unknown
- 1997-09-08 EP EP97939315A patent/EP0954524B1/en not_active Expired - Lifetime
-
1999
- 1999-03-11 NO NO19991208A patent/NO323217B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2265929A1 (en) | 1998-03-19 |
| ATE236925T1 (de) | 2003-04-15 |
| NZ334589A (en) | 2000-07-28 |
| AU729536B2 (en) | 2001-02-01 |
| WO1998011127A1 (en) | 1998-03-19 |
| NO991208D0 (no) | 1999-03-11 |
| DE69720786T2 (de) | 2003-11-06 |
| NO991208L (no) | 1999-05-11 |
| JP2001500154A (ja) | 2001-01-09 |
| AU4143097A (en) | 1998-04-02 |
| PT954524E (pt) | 2003-08-29 |
| DE69720786D1 (de) | 2003-05-15 |
| ES2197361T3 (es) | 2004-01-01 |
| EP0954524B1 (en) | 2003-04-09 |
| DK0954524T3 (da) | 2003-08-04 |
| EP0954524A1 (en) | 1999-11-10 |
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