NO20075272L - Human GLP-1 "mimetibodies", compositions, methods and applications - Google Patents

Human GLP-1 "mimetibodies", compositions, methods and applications

Info

Publication number
NO20075272L
NO20075272L NO20075272A NO20075272A NO20075272L NO 20075272 L NO20075272 L NO 20075272L NO 20075272 A NO20075272 A NO 20075272A NO 20075272 A NO20075272 A NO 20075272A NO 20075272 L NO20075272 L NO 20075272L
Authority
NO
Norway
Prior art keywords
methods
compositions
glp
mimetibodies
applications
Prior art date
Application number
NO20075272A
Other languages
Norwegian (no)
Inventor
Kristen Picha
Karyn T O'neil
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of NO20075272L publication Critical patent/NO20075272L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Sammendrag Den foreliggende oppfinnelsen er relatert til minst en ny human GLP-1 mimetibody eller spesifisert del eller variant, inkluderende isolerte nukleinsyrer som koder for minst en GLP-1 mimetibody eller spesifisert del eller variant, GLP-1 mimetibody eller spesifisert del eller varianter, vektorer, vertsceller, transgene dyr eller planter, og fremgangsmåter for tillaging og anvendelse derav, inkluderende terapeutiske sammensetninger, fremgangsmåter og anordninger.SUMMARY The present invention relates to at least one new human GLP-1 mimetibody or specified part or variant, including isolated nucleic acids encoding at least one GLP-1 mimetibody or specified part or variant, GLP-1 mimetibody or specified part or variants, vectors , host cells, transgenic animals or plants, and methods of preparation and use thereof, including therapeutic compositions, methods and devices.

NO20075272A 2005-03-28 2007-10-15 Human GLP-1 "mimetibodies", compositions, methods and applications NO20075272L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2005097175 2005-03-28
PCT/US2005/046884 WO2007081302A2 (en) 2005-03-28 2005-12-22 Human glp-1 mimetibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
NO20075272L true NO20075272L (en) 2007-12-28

Family

ID=38256744

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075272A NO20075272L (en) 2005-03-28 2007-10-15 Human GLP-1 "mimetibodies", compositions, methods and applications

Country Status (12)

Country Link
EP (1) EP1871811A4 (en)
JP (1) JP2008546373A (en)
KR (1) KR20080005378A (en)
CN (1) CN101389346A (en)
AU (1) AU2005339797A1 (en)
BR (1) BRPI0520168A2 (en)
CA (1) CA2603359A1 (en)
CR (1) CR9481A (en)
IL (1) IL186307A0 (en)
MX (1) MX2007011975A (en)
NO (1) NO20075272L (en)
WO (1) WO2007081302A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200843794A (en) 2006-12-21 2008-11-16 Centocor Inc Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles
CN111574583B (en) * 2020-04-10 2021-06-25 上海海路生物技术有限公司 Protein renaturation reagent and its application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656728B1 (en) * 1999-02-08 2003-12-02 Chiron Corporation Fibroblast growth factor receptor-immunoglobulin fusion
CZ306180B6 (en) * 2000-12-07 2016-09-14 Eli Lilly And Company GLP-1 fusion proteins
CA2490411A1 (en) * 2002-06-28 2004-01-08 Centocor, Inc. Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
JP2006504406A (en) * 2002-06-28 2006-02-09 セントカー・インコーポレーテツド Mammalian CH1-deficient mimetibodies, compositions, methods and uses
US20050033029A1 (en) * 2003-06-30 2005-02-10 Jin Lu Engineered anti-target immunoglobulin derived proteins, compositions, methods and uses
WO2005097175A2 (en) * 2004-03-31 2005-10-20 Centocor, Inc. Human glp-1 mimetibodies, compositions, methods and uses

Also Published As

Publication number Publication date
JP2008546373A (en) 2008-12-25
IL186307A0 (en) 2008-01-20
CA2603359A1 (en) 2007-07-19
KR20080005378A (en) 2008-01-11
EP1871811A2 (en) 2008-01-02
CR9481A (en) 2009-01-14
BRPI0520168A2 (en) 2009-04-22
EP1871811A4 (en) 2009-07-22
CN101389346A (en) 2009-03-18
MX2007011975A (en) 2008-03-14
WO2007081302A3 (en) 2008-11-13
AU2005339797A1 (en) 2007-07-19
WO2007081302A2 (en) 2007-07-19

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application