NO20073728L - Oral immediate release formulation of a poorly water-soluble active substance - Google Patents

Oral immediate release formulation of a poorly water-soluble active substance

Info

Publication number
NO20073728L
NO20073728L NO20073728A NO20073728A NO20073728L NO 20073728 L NO20073728 L NO 20073728L NO 20073728 A NO20073728 A NO 20073728A NO 20073728 A NO20073728 A NO 20073728A NO 20073728 L NO20073728 L NO 20073728L
Authority
NO
Norway
Prior art keywords
active substance
release formulation
immediate release
poorly water
oral immediate
Prior art date
Application number
NO20073728A
Other languages
Norwegian (no)
Inventor
Rajesh Jain
Marius L De Winter
Sukhjeet Singh
Rohit Kumar
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2005/056970 external-priority patent/WO2006067150A1/en
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of NO20073728L publication Critical patent/NO20073728L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Oppfinnelsen vedrører en oral umiddelbar frigivelsesformulering av Benzazepin-leddiksyrederivater som innbefatter: a) nevnte aktive substans i en mengde på opptil 65 % av den totale vekten av formuleringen; b) minst 10 % vekt/vekt av en alkalisk forbindelse eller en blanding av alkaliske forbindelser; c) mellom 0,1 og 10 % av en eller flere overflateaktive midler, og d) eventuelt omfatter hjelpematerialer i en mengde på mellom 1 % og 45 % av den totale vekten av formuleringen.The invention relates to an oral immediate-release formulation of benzazepine-acetic acid derivatives comprising: a) said active substance in an amount of up to 65% of the total weight of the formulation; b) at least 10% w / w of an alkaline compound or a mixture of alkaline compounds; c) between 0.1 and 10% of one or more surfactants, and d) optionally comprises auxiliary materials in an amount of between 1% and 45% of the total weight of the formulation.

NO20073728A 2004-12-23 2007-07-18 Oral immediate release formulation of a poorly water-soluble active substance NO20073728L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63811104P 2004-12-23 2004-12-23
EP04106933 2004-12-23
PCT/EP2005/056970 WO2006067150A1 (en) 2004-12-23 2005-12-20 Oral immediate release formulation of a poorly watersoluble active substance

Publications (1)

Publication Number Publication Date
NO20073728L true NO20073728L (en) 2007-07-18

Family

ID=35890662

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073728A NO20073728L (en) 2004-12-23 2007-07-18 Oral immediate release formulation of a poorly water-soluble active substance

Country Status (4)

Country Link
KR (1) KR20070104890A (en)
DE (1) DE602005019919D1 (en)
IL (1) IL183554A (en)
NO (1) NO20073728L (en)

Also Published As

Publication number Publication date
DE602005019919D1 (en) 2010-04-22
IL183554A (en) 2011-07-31
KR20070104890A (en) 2007-10-29
IL183554A0 (en) 2007-09-20

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application