NO20072520L - Novel intermediates, process for their preparation and synthesis of 1,4-benzoquinones - Google Patents
Novel intermediates, process for their preparation and synthesis of 1,4-benzoquinonesInfo
- Publication number
- NO20072520L NO20072520L NO20072520A NO20072520A NO20072520L NO 20072520 L NO20072520 L NO 20072520L NO 20072520 A NO20072520 A NO 20072520A NO 20072520 A NO20072520 A NO 20072520A NO 20072520 L NO20072520 L NO 20072520L
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- group
- preparation
- benzyl
- phenyl
- alkyl
- Prior art date
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Det beskrives en fremgangsmåte for fremstilling av 1,4-benzoquioner av formel (II) (II) hvor R1, R2, R3og R4 er uavhengig valgt blant gruppen omfattende forgrenet eller ikke-forgrenet C1-C6, alkyl, fenyl og benzyl, hvor fenyl og benzyl er valgfritt substituert av én eller flere substituenter uavhengig valgt blant gruppen omfattende C1-C6 alkyl og halogen og hvor C1-C6, alkyl er valgfritt substituert med én eller flere halogensubstituenter, og hvor R2 og R3 sammen kan danne en C1-C6-alkylenradikal, valgfritt substituert av én eller flere substituenter uavhengig valgt blant gruppen omfattende C1-C6, benzyl, fenyl og halogen. En foretrukket forbindelse er 2,3-dimetoksy-5-metyl-[1,4]-benzoquinon, også kjent som koenzym Q0 (CoQ0). Også beskrevet er nye forbindelser og mellomprodukter, og en fremgangsmåte for fremstilling av koenzym Qn, fortrinnsvis koenzym Q0. Også beskrevet er en fremgangsmåte for kontinuerlig syntese av 1,4-benzoquioner i en kontinuerlig strømningsreaktor.There is disclosed a process for the preparation of 1,4-benzoquions of formula (II) (II) wherein R 1, R 2, R 3 and R 4 are independently selected from the group consisting of branched or unbranched C 1 -C 6, alkyl, phenyl and benzyl, wherein phenyl and benzyl is optionally substituted by one or more substituents independently selected from the group comprising C1-C6 alkyl and halogen and wherein C1-C6, alkyl is optionally substituted by one or more halogen substituents, and wherein R2 and R3 may together form a C1-C6 group. alkylene radical, optionally substituted by one or more substituents independently selected from the group comprising C1-C6, benzyl, phenyl and halogen. A preferred compound is 2,3-dimethoxy-5-methyl- [1,4] -benzoquinone, also known as coenzyme Q0 (CoQ0). Also disclosed are novel compounds and intermediates, and a process for producing coenzyme Qn, preferably coenzyme Q0. Also described is a process for the continuous synthesis of 1,4-benzoquions in a continuous flow reactor.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20072520A NO20072520L (en) | 2007-05-16 | 2007-05-16 | Novel intermediates, process for their preparation and synthesis of 1,4-benzoquinones |
PCT/NO2008/000172 WO2008140328A2 (en) | 2007-05-16 | 2008-05-16 | Novel intermediates, process for their preparation and synthesis of 1,4-benzoquinones |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20072520A NO20072520L (en) | 2007-05-16 | 2007-05-16 | Novel intermediates, process for their preparation and synthesis of 1,4-benzoquinones |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20072520L true NO20072520L (en) | 2008-11-17 |
Family
ID=40383506
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20072520A NO20072520L (en) | 2007-05-16 | 2007-05-16 | Novel intermediates, process for their preparation and synthesis of 1,4-benzoquinones |
Country Status (1)
Country | Link |
---|---|
NO (1) | NO20072520L (en) |
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2007
- 2007-05-16 NO NO20072520A patent/NO20072520L/en not_active Application Discontinuation
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