NO20060669L - Modafinilsammensetninger - Google Patents
ModafinilsammensetningerInfo
- Publication number
- NO20060669L NO20060669L NO20060669A NO20060669A NO20060669L NO 20060669 L NO20060669 L NO 20060669L NO 20060669 A NO20060669 A NO 20060669A NO 20060669 A NO20060669 A NO 20060669A NO 20060669 L NO20060669 L NO 20060669L
- Authority
- NO
- Norway
- Prior art keywords
- modulated
- modafinil
- enantiomerically
- modafinilsammensetninger
- solvates
- Prior art date
Links
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 abstract 2
- 229960001165 modafinil Drugs 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 1
- 231100000673 dose–response relationship Toxicity 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000000704 physical effect Effects 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det blir fremstilt ko-krystaller og solvater av racemisk, enantiomert ren og enantiomert blandet modafinil, og flere viktige fysiske egenskaper blir modulert. Løselighet, oppløsning, biotilgjengelighet, doserespons og stabilitet til modafinil kan moduleres for å forbedre effektiviteten i farmasøytiske preparater.Co-crystals and solvates of racemic, enantiomerically pure and enantiomerically mixed modafinil are prepared, and several important physical properties are modulated. Solubility, resolution, bioavailability, dose response and stability to modafinil can be modulated to improve the efficacy of pharmaceutical preparations.
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/660,202 US7927613B2 (en) | 2002-02-15 | 2003-09-11 | Pharmaceutical co-crystal compositions |
| US50820803P | 2003-10-02 | 2003-10-02 | |
| US54275204P | 2004-02-06 | 2004-02-06 | |
| PCT/US2004/006288 WO2004078163A2 (en) | 2003-02-28 | 2004-02-26 | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| US56041104P | 2004-04-06 | 2004-04-06 | |
| US57341204P | 2004-05-21 | 2004-05-21 | |
| US57917604P | 2004-06-12 | 2004-06-12 | |
| US58199204P | 2004-06-22 | 2004-06-22 | |
| US58675204P | 2004-07-09 | 2004-07-09 | |
| US58823604P | 2004-07-15 | 2004-07-15 | |
| PCT/US2004/029013 WO2005023198A2 (en) | 2003-09-04 | 2004-09-04 | Modafinil compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20060669L true NO20060669L (en) | 2006-06-02 |
Family
ID=36763171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20060669A NO20060669L (en) | 2003-09-11 | 2006-02-10 | Modafinilsammensetninger |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1670753A4 (en) |
| JP (1) | JP4842819B2 (en) |
| IL (2) | IL173575A0 (en) |
| NO (1) | NO20060669L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010099323A1 (en) | 2009-02-26 | 2010-09-02 | Thar Pharmaceuticals, Inc. | Crystalization of pharmaceutical compounds |
| WO2013147072A1 (en) * | 2012-03-29 | 2013-10-03 | 大鵬薬品工業株式会社 | Cocrystal of 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2593809B1 (en) * | 1986-01-31 | 1988-07-22 | Lafon Labor | BENZHYDRYLSULFINYLACETAMIDE, PROCESS FOR PREPARATION AND THERAPEUTIC USE |
| KR101098749B1 (en) * | 2000-07-27 | 2011-12-23 | 테바 파마슈티컬 인더스트리즈 리미티드 | Crystalline and pure modafinil, and process of preparing the same |
| IL143106A (en) * | 2001-05-13 | 2005-11-20 | Chemagis Ltd | Process for the preparation of diphenylmethylthioacetamide |
| FR2849029B1 (en) * | 2002-12-20 | 2005-03-18 | Lafon Labor | PROCESS FOR THE PREPARATION AND CRYSTALLINE FORMS OF OPTICAL ENANTIOMERS OF MODAFINIL. |
| AU2003272270A1 (en) * | 2003-02-28 | 2004-09-28 | The Regents Of The University Of Michigan | Pharmaceutical co-crystal compositions of drugs such as carbamazeptine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| CA2514733A1 (en) * | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
-
2004
- 2004-09-04 EP EP20040783308 patent/EP1670753A4/en not_active Withdrawn
- 2004-09-04 JP JP2006525508A patent/JP4842819B2/en not_active Expired - Fee Related
-
2006
- 2006-02-07 IL IL173575A patent/IL173575A0/en unknown
- 2006-02-10 NO NO20060669A patent/NO20060669L/en not_active Application Discontinuation
-
2009
- 2009-06-03 IL IL199140A patent/IL199140A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL199140A (en) | 2012-07-31 |
| JP4842819B2 (en) | 2011-12-21 |
| IL173575A0 (en) | 2006-07-05 |
| JP2007513867A (en) | 2007-05-31 |
| EP1670753A4 (en) | 2008-01-02 |
| EP1670753A2 (en) | 2006-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |