NO20060154L - Imidazolyl derivatives - Google Patents
Imidazolyl derivativesInfo
- Publication number
- NO20060154L NO20060154L NO20060154A NO20060154A NO20060154L NO 20060154 L NO20060154 L NO 20060154L NO 20060154 A NO20060154 A NO 20060154A NO 20060154 A NO20060154 A NO 20060154A NO 20060154 L NO20060154 L NO 20060154L
- Authority
- NO
- Norway
- Prior art keywords
- imidazolyl derivatives
- imidazolyl
- derivatives
- somatostat
- agonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/12—Antidiarrhoeals
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Foreliggende oppfinnelse angår imidazolyl-derivater med formel (I) hvor substituentene er definert i beskrivelsen, som er anvendelige som agonister eller antagonister for somatostatmreseptorerThe present invention relates to imidazolyl derivatives of formula (I) wherein the substituents are defined in the specification which are useful as agonists or antagonists for somatostat receptors
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8908798P | 1998-06-12 | 1998-06-12 | |
US9643198A | 1998-06-12 | 1998-06-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20060154L true NO20060154L (en) | 1999-12-13 |
Family
ID=26780237
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20006267A NO20006267L (en) | 1998-06-12 | 2000-12-11 | Imidazolyl derivatives |
NO20060154A NO20060154L (en) | 1998-06-12 | 2006-01-10 | Imidazolyl derivatives |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20006267A NO20006267L (en) | 1998-06-12 | 2000-12-11 | Imidazolyl derivatives |
Country Status (21)
Country | Link |
---|---|
US (3) | US6852725B1 (en) |
EP (1) | EP1086086B1 (en) |
JP (1) | JP2003523921A (en) |
CN (1) | CN1319094A (en) |
AR (1) | AR018671A1 (en) |
AT (1) | ATE279396T1 (en) |
AU (1) | AU746963B2 (en) |
CA (1) | CA2334945A1 (en) |
CZ (1) | CZ20004568A3 (en) |
DE (1) | DE69921124T2 (en) |
DK (1) | DK1086086T3 (en) |
ES (1) | ES2229718T3 (en) |
HK (1) | HK1031873A1 (en) |
HU (1) | HUP0202648A3 (en) |
IL (1) | IL139835A (en) |
NO (2) | NO20006267L (en) |
PL (1) | PL347139A1 (en) |
PT (1) | PT1086086E (en) |
RU (1) | RU2263111C2 (en) |
TW (1) | TWI245758B (en) |
WO (1) | WO1999064401A2 (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2334945A1 (en) | 1998-06-12 | 1999-12-16 | Christophe Alain Thurieau | Imidazolyl derivatives |
US6518292B1 (en) | 1999-03-12 | 2003-02-11 | Bristol-Myers Squibb Co. | Heterocyclic aromatic compounds usefuls as growth hormone secretagogues |
US6525203B1 (en) | 1999-03-12 | 2003-02-25 | Bristol-Myers Squibb Company | Heterocyclic aromatic compounds useful as growth hormone secretagogues |
AU3673300A (en) * | 1999-04-07 | 2000-11-14 | Santen Pharmaceutical Co. Ltd. | N-substituted-n'-substituted urea derivative and use thereof as tnf-alpha production inhibitor |
FR2796945B1 (en) * | 1999-07-30 | 2002-06-28 | Sod Conseils Rech Applic | NOVEL DERIVATIVES OF HYDANTOINS, THIOHYDANTOINS, PYRIMIDINEDIONES AND THIOXOPYRIMIDINONES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS |
US6696418B1 (en) | 1999-09-01 | 2004-02-24 | Pfizer Inc. | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor |
TWI283577B (en) * | 1999-10-11 | 2007-07-11 | Sod Conseils Rech Applic | Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof |
FR2812546B1 (en) * | 2000-08-01 | 2008-11-21 | Sod Conseils Rech Applic | 5-CHAIN HETEROCYCLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS |
WO2001032639A1 (en) | 1999-11-04 | 2001-05-10 | Ortho-Mcneil Pharmaceutical, Inc. | Nonpeptide substituted benzothiazepines as vasopressin antagonists |
US6495589B2 (en) | 2000-04-28 | 2002-12-17 | Pfizer Inc. | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor |
US6372795B1 (en) * | 2000-06-30 | 2002-04-16 | Unilever Home And Personal Care Usa, A Division Of Conopco, Inc. | Cosmetic compositions containing substituted amide derivatives |
KR20030020960A (en) | 2000-08-01 | 2003-03-10 | 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. | Imidazolyl derivatives |
US6653478B2 (en) | 2000-10-27 | 2003-11-25 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide Y modulators |
US6720330B2 (en) | 2000-11-17 | 2004-04-13 | Pfizer Inc. | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor |
HUP0400367A2 (en) * | 2001-06-25 | 2006-03-28 | Conseil De Rech S Et D Applic | Use of somatostatin receptor agonists for preparation of pharmaceutical compositions which inhibit proliferation of pituitary adenomas |
CZ2004760A3 (en) * | 2001-11-28 | 2005-01-12 | Société De Conseils De Recherches Et D'applicatio | 5-Sulfanyl-4H-1,2,4-triazole derivatives, process of their preparation and their use as a medicament |
FR2832710B1 (en) * | 2001-11-28 | 2004-09-03 | Sod Conseils Rech Applic | 5-SULFANYL-4H-1,2,4-TRIAZOLES DERIVATIVES AND THEIR USE AS MEDICAMENTS |
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US7453002B2 (en) | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
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TW200800951A (en) * | 2005-08-09 | 2008-01-01 | Novartis Ag | Substituted imidazole compounds as KSP inhibitors |
GB0522130D0 (en) * | 2005-10-31 | 2005-12-07 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
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KR20080087817A (en) * | 2005-12-14 | 2008-10-01 | 브리스톨-마이어스 스큅 컴퍼니 | Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor xia inhibitors |
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AR077463A1 (en) | 2009-07-09 | 2011-08-31 | Irm Llc | IMIDAZO DERIVATIVES [1, 2 - A] PIRAZINA AND ITS USE IN MEDICINES FOR THE TREATMENT OF PARASITARY DISEASES |
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1999
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- 1999-06-08 JP JP2000553410A patent/JP2003523921A/en active Pending
- 1999-06-08 DE DE69921124T patent/DE69921124T2/en not_active Expired - Fee Related
- 1999-06-08 PT PT99927323T patent/PT1086086E/en unknown
- 1999-06-08 CN CN99807324A patent/CN1319094A/en active Pending
- 1999-06-08 ES ES99927323T patent/ES2229718T3/en not_active Expired - Lifetime
- 1999-06-08 US US09/719,457 patent/US6852725B1/en not_active Expired - Fee Related
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- 1999-06-08 AT AT99927323T patent/ATE279396T1/en not_active IP Right Cessation
- 1999-06-08 DK DK99927323T patent/DK1086086T3/en active
- 1999-06-08 EP EP99927323A patent/EP1086086B1/en not_active Expired - Lifetime
- 1999-06-08 WO PCT/US1999/012760 patent/WO1999064401A2/en not_active Application Discontinuation
- 1999-06-08 RU RU2001101429/04A patent/RU2263111C2/en not_active IP Right Cessation
- 1999-06-08 PL PL99347139A patent/PL347139A1/en not_active Application Discontinuation
- 1999-06-08 CZ CZ20004568A patent/CZ20004568A3/en unknown
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- 1999-06-11 AR ARP990102811A patent/AR018671A1/en unknown
- 1999-08-11 TW TW088109822A patent/TWI245758B/en active
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2000
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2001
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CN1319094A (en) | 2001-10-24 |
JP2003523921A (en) | 2003-08-12 |
PT1086086E (en) | 2005-02-28 |
AR018671A1 (en) | 2001-11-28 |
PL347139A1 (en) | 2002-03-25 |
TWI245758B (en) | 2005-12-21 |
RU2263111C2 (en) | 2005-10-27 |
HK1031873A1 (en) | 2001-06-29 |
AU746963B2 (en) | 2002-05-09 |
HUP0202648A3 (en) | 2003-02-28 |
ATE279396T1 (en) | 2004-10-15 |
DE69921124D1 (en) | 2004-11-18 |
WO1999064401A2 (en) | 1999-12-16 |
DK1086086T3 (en) | 2005-01-24 |
EP1086086A1 (en) | 2001-03-28 |
US6852725B1 (en) | 2005-02-08 |
CA2334945A1 (en) | 1999-12-16 |
US7238695B2 (en) | 2007-07-03 |
DE69921124T2 (en) | 2005-11-10 |
US20070299073A1 (en) | 2007-12-27 |
HUP0202648A2 (en) | 2002-12-28 |
IL139835A0 (en) | 2002-02-10 |
US20040176379A1 (en) | 2004-09-09 |
WO1999064401A3 (en) | 2003-04-17 |
CZ20004568A3 (en) | 2001-11-14 |
IL139835A (en) | 2005-11-20 |
NO20006267L (en) | 2001-02-07 |
EP1086086B1 (en) | 2004-10-13 |
ES2229718T3 (en) | 2005-04-16 |
AU4425799A (en) | 1999-12-30 |
NO20006267D0 (en) | 2000-12-11 |
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