NO20055998L - Diarylmetylidenpiperidinderivater, preparater derav og anvendelse derav - Google Patents

Diarylmetylidenpiperidinderivater, preparater derav og anvendelse derav

Info

Publication number
NO20055998L
NO20055998L NO20055998A NO20055998A NO20055998L NO 20055998 L NO20055998 L NO 20055998L NO 20055998 A NO20055998 A NO 20055998A NO 20055998 A NO20055998 A NO 20055998A NO 20055998 L NO20055998 L NO 20055998L
Authority
NO
Norway
Prior art keywords
preparations
piperidine derivatives
diarylmethylidene piperidine
diarylmethylidene
compounds
Prior art date
Application number
NO20055998A
Other languages
English (en)
Inventor
William L Brown
Andrew Griffin
Shujuan Jin
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0301444A external-priority patent/SE0301444D0/xx
Priority claimed from SE0400024A external-priority patent/SE0400024D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20055998L publication Critical patent/NO20055998L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Forbindelser av formel: hvori R\ R^, R^, R'' og R^ er som definert i spesifikasjonen, også som salter, enantiomerer derav og farmasøytiske inkluderende forbindelsene som er dannet. De er nyttige innen terapi, spesielt innen behandling av smerte.
NO20055998A 2003-05-16 2005-12-16 Diarylmetylidenpiperidinderivater, preparater derav og anvendelse derav NO20055998L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0301444A SE0301444D0 (sv) 2003-05-16 2003-05-16 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0400024A SE0400024D0 (sv) 2004-01-09 2004-01-09 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
PCT/GB2004/002074 WO2004101522A1 (en) 2003-05-16 2004-05-13 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof

Publications (1)

Publication Number Publication Date
NO20055998L true NO20055998L (no) 2006-02-13

Family

ID=33455733

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055998A NO20055998L (no) 2003-05-16 2005-12-16 Diarylmetylidenpiperidinderivater, preparater derav og anvendelse derav

Country Status (15)

Country Link
US (2) US20070099957A1 (no)
EP (1) EP1641757A1 (no)
JP (1) JP2007503457A (no)
KR (1) KR20060010811A (no)
AR (1) AR044346A1 (no)
AU (1) AU2004238618A1 (no)
BR (1) BRPI0410347A (no)
CA (1) CA2525860A1 (no)
CO (1) CO5630032A2 (no)
IS (1) IS8182A (no)
MX (1) MXPA05012117A (no)
NO (1) NO20055998L (no)
RU (1) RU2005136524A (no)
TW (1) TW200512192A (no)
WO (1) WO2004101522A1 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0203301D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0402485D0 (sv) 2004-10-13 2004-10-13 Astrazeneca Ab Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt
MY148880A (en) * 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2898338A (en) * 1954-06-22 1959-08-04 Schering Corp Phenyl, (2-pyridyl)propane derivatives
US2898339A (en) * 1957-07-29 1959-08-04 Wm S Merrell Co N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en) * 1983-07-27 1986-04-08 Janssen Pharmaceutica, N.V. [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5140029A (en) * 1989-01-09 1992-08-18 Janssen Pharmaceutica N.V. 2-aminopyrimidinone derivatives
US4939137A (en) * 1989-06-28 1990-07-03 Ortho Pharmaceutical Corporation Ring-fused thienopyrimidinedione derivatives
US5683998A (en) * 1991-04-23 1997-11-04 Toray Industries, Inc. Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
US5807858A (en) * 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
US5574159A (en) * 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
AU2001241676A1 (en) * 2000-03-03 2001-09-17 Ortho-Mcneil Pharmaceutical, Inc. 3-(diarylmethylene)-8-azabicyclo(3.2.1)octane derivatives
US6556387B1 (en) * 2000-03-31 2003-04-29 Seagate Technology Llc Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0001208D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0101766D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101767D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101768D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101765D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0103313D0 (sv) * 2001-10-03 2001-10-03 Astrazeneca Ab Novel compounds
SE0203301D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0300103D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300104D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300105D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE0400026D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0400025D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
MY148880A (en) * 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression

Also Published As

Publication number Publication date
IS8182A (is) 2005-12-14
US20070099957A1 (en) 2007-05-03
WO2004101522A1 (en) 2004-11-25
TW200512192A (en) 2005-04-01
AU2004238618A1 (en) 2004-11-25
JP2007503457A (ja) 2007-02-22
CO5630032A2 (es) 2006-04-28
RU2005136524A (ru) 2006-06-27
EP1641757A1 (en) 2006-04-05
KR20060010811A (ko) 2006-02-02
BRPI0410347A (pt) 2006-05-30
MXPA05012117A (es) 2006-02-08
AR044346A1 (es) 2005-09-07
US20110082173A1 (en) 2011-04-07
CA2525860A1 (en) 2004-11-25

Similar Documents

Publication Publication Date Title
NO20065904L (no) Terapeutiske forbindelser
SE0401971D0 (sv) Piperidne derivatives
NO20053809L (no) Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav
NO20052698L (no) 4(fenylpiperazinyl-metyl)benzamid-derivater og deres anvendelse ved behandling av smerte og gasatrintestinale lidelser.
NO20052699L (no) 4(fenylpiperazinyl-metyl)benzamid-derivater og deres anvendelse ved behandling av smerte og gastrointestinale lidelser.
NO20052182L (no) Nye forbindelser
NO20063619L (no) Diarylmetylpiperazinderivater, fremstilling og anvendelse derav
MY140630A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
TW200504029A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0301320D0 (sv) Positive modulators of nicotinic acetylcholine receptors
TW200504030A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
NO20055997L (no) Diarylmetylidenpiperidinderivater og deres anvendelse som opiodreseptoragonister
NO20053805L (no) Diarylmetylindenpiperidinderivater, framgangsmate for fremstilling derav, og anvendelse derav
NO20055998L (no) Diarylmetylidenpiperidinderivater, preparater derav og anvendelse derav
NO20055142L (no) Diarylmetylidenpiperidinderivater, fremstillinger og anvendelser derav
ATE440835T1 (de) Heterozyklische harnstoff-derivate für die behandlung von schmerzen.
TW200510313A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
WO2003051276A3 (en) Therapeutic heterocycles
NO20063618L (no) Diarylmetylpiperidinderivater, fremstilling og anvendelse derav
NO20063617L (no) Diarylmetylidenpiperidinderivater, fremstilling og anvendelse derav
NO20063353L (no) 1,2,3,4-tetrahydroisokinolinderivater, fremgangsmate for fremstilling derav og anvendelser derav
TW200500356A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
TW200504018A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0303075D0 (sv) 4-substituted imidazoles
TW200507842A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application