NO20053203L - Combination of local ester anesthetics. - Google Patents

Combination of local ester anesthetics.

Info

Publication number
NO20053203L
NO20053203L NO20053203A NO20053203A NO20053203L NO 20053203 L NO20053203 L NO 20053203L NO 20053203 A NO20053203 A NO 20053203A NO 20053203 A NO20053203 A NO 20053203A NO 20053203 L NO20053203 L NO 20053203L
Authority
NO
Norway
Prior art keywords
combination
ester anesthetics
action
analgesia
onset
Prior art date
Application number
NO20053203A
Other languages
Norwegian (no)
Other versions
NO20053203D0 (en
Inventor
Steven L Shafer
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of NO20053203D0 publication Critical patent/NO20053203D0/en
Publication of NO20053203L publication Critical patent/NO20053203L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/625—Salicylic acid; Derivatives thereof having heterocyclic substituents, e.g. 4-salicycloylmorpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Abstract

Det tilveiebringes preparater og metoder for forbedret lokalanestesi og/eller analgesi der virkningsstarten er hurtig, risikoen for toksisitet er lav og effekten opprettholdes. Mer spesielt tilveiebringes det en kombinasjon av minst to esteranestetika fot administrering til et individ der minst et esteranestetikum gir en hurtig virkningsstart og minst et gir opprettholdt aktivitet. Preparatene ifølge oppfinnelsen er brukbare for å oppnå analgesi og/eller anestesi og er spesielt nyttige ved profylakse og/eller terapi av smerte.Preparations and methods for improved local anesthesia and / or analgesia are provided where the onset of action is rapid, the risk of toxicity is low and the effect is maintained. More particularly, there is provided a combination of at least two ester anesthetics for administration to an individual where at least one ester anesthetic provides a rapid onset of action and at least one provides sustained activity. The compositions of the invention are useful for achieving analgesia and / or anesthesia and are particularly useful in the prophylaxis and / or therapy of pain.

NO20053203A 2002-12-20 2005-06-30 Combination of local ester anesthetics. NO20053203L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32731002A 2002-12-20 2002-12-20
PCT/US2003/041219 WO2004058329A2 (en) 2002-12-20 2003-12-18 Ester combination local anesthetic

Publications (2)

Publication Number Publication Date
NO20053203D0 NO20053203D0 (en) 2005-06-30
NO20053203L true NO20053203L (en) 2005-09-19

Family

ID=32680753

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053203A NO20053203L (en) 2002-12-20 2005-06-30 Combination of local ester anesthetics.

Country Status (10)

Country Link
EP (1) EP1572218A4 (en)
JP (1) JP2006513224A (en)
KR (1) KR20050085736A (en)
CN (1) CN1729004A (en)
AU (1) AU2003299885A1 (en)
BR (1) BR0317519A (en)
CA (1) CA2507511A1 (en)
MX (1) MXPA05006771A (en)
NO (1) NO20053203L (en)
WO (1) WO2004058329A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060062836A1 (en) * 2004-09-21 2006-03-23 Carter Stephen G Methods of device-assisted drug delivery
EP1863469B1 (en) 2005-03-15 2011-12-21 Animal Ethics Pty Ltd A topical analgesic composition
ITMI20051633A1 (en) * 2005-09-06 2007-03-07 Sint Sa NEW USE OF A COMPOSITION INCLUDING CHOROPROCAINE HCL NEW COMPOSITION INCLUDING CHLOROPROCAINE HCL AND METHOD FOR ITS MANUFACTURING
US20100056575A1 (en) * 2006-07-19 2010-03-04 Jenkins Thomas E Anesthetic Compounds
US20080220062A1 (en) * 2006-10-23 2008-09-11 Psivida, Inc. Sustained release of agents for localized pain management
WO2009091546A1 (en) * 2008-01-18 2009-07-23 Pharmacofore, Inc. Anesthetic compounds
ITMI20122120A1 (en) 2012-12-12 2014-06-13 Sint Sa PHARMACEUTICAL COMPOSITION BASED ON CHLOROPROCAIN FOR REPEATED INTRATECAL ADMINISTRATION
ITCR20130004A1 (en) * 2013-02-05 2014-08-06 Vincenzo Vigna SALVAVITA DRUG
US10117847B2 (en) * 2015-12-04 2018-11-06 Ventis Pharma Extended duration local anesthetic formulation
DE102016215037A1 (en) 2016-08-11 2018-02-15 Franz Baur Spring device and connecting device
CU20200019A7 (en) * 2017-09-15 2020-11-30 Sintetica S A TOPICAL CHLOROPROCAINE FORMULATIONS AND METHODS TO PREPARE THEM
WO2019226599A1 (en) * 2018-05-22 2019-11-28 Alkalidx, Inc. Diagnostics and treatments of anesthetic insensitive subjects
JP6886551B1 (en) * 2020-11-06 2021-06-16 医療法人祥和会 Local anesthetic for dentistry

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
AU7389098A (en) * 1997-05-16 1998-12-08 Brigham And Women's Hospital Local anesthetic formulations
US7273887B1 (en) * 1999-10-22 2007-09-25 Transdermatech, Inc. Topical anesthetic formulation
US6383511B1 (en) * 1999-10-25 2002-05-07 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
AU2001231189A1 (en) * 2000-01-27 2001-08-07 Childrens Hospital Research Foundation Transdermal anesthetic and vasodilator composition and methods for topical administration

Also Published As

Publication number Publication date
EP1572218A2 (en) 2005-09-14
BR0317519A (en) 2005-11-16
JP2006513224A (en) 2006-04-20
WO2004058329A3 (en) 2004-12-29
NO20053203D0 (en) 2005-06-30
AU2003299885A1 (en) 2004-07-22
CN1729004A (en) 2006-02-01
KR20050085736A (en) 2005-08-29
MXPA05006771A (en) 2005-09-08
EP1572218A4 (en) 2007-05-16
WO2004058329A2 (en) 2004-07-15
CA2507511A1 (en) 2004-07-15

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application