NO20052286L - Process for the recovery of a natural blend of conjugated equine estrogens with a greatly reduced content of non-conjugated lipophilic compounds - Google Patents
Process for the recovery of a natural blend of conjugated equine estrogens with a greatly reduced content of non-conjugated lipophilic compoundsInfo
- Publication number
- NO20052286L NO20052286L NO20052286A NO20052286A NO20052286L NO 20052286 L NO20052286 L NO 20052286L NO 20052286 A NO20052286 A NO 20052286A NO 20052286 A NO20052286 A NO 20052286A NO 20052286 L NO20052286 L NO 20052286L
- Authority
- NO
- Norway
- Prior art keywords
- conjugated
- equine estrogens
- recovery
- greatly reduced
- lipophilic compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Extraction Or Liquid Replacement (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Det beskrives en fremgangsmåte for utvirming av en ekstiakt irmeholdende den naturlige blanding av konjugerte hesteøstrogener, ved væske-væske-ekstraksjon av blandingen av konjugerte hesteøstrogener. Den ekstraherte blanding er utarmet på ikke-konjugerte lipofile forbindelser av gruppen omfattende ikke-konjugerte flavonoider, ikke-konjugerte isoflavonoider, ikke-konjugerte norisoprenoider, ikke-konjugerte steroider, spesielt androstan- og pregnansteroider, og lignende ikke-konjugerte forbindelser.There is disclosed a method of producing an oxyact containing the natural mixture of conjugated equine estrogens, by liquid-liquid extraction of the mixture of conjugated equine estrogens. The extracted mixture is depleted of non-conjugated lipophilic compounds of the group comprising non-conjugated flavonoids, non-conjugated isoflavonoids, non-conjugated norisoprenoids, non-conjugated steroids, especially androstan and pregnancy steroids, and similar non-conjugated compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02022763 | 2002-10-11 | ||
| PCT/EP2003/050703 WO2004035067A1 (en) | 2002-10-11 | 2003-10-08 | Method for extracting a natural mixture of conjugated equine estrogens that is depleted of non-conjugated lipophilic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20052286L true NO20052286L (en) | 2005-05-10 |
| NO20052286D0 NO20052286D0 (en) | 2005-05-10 |
| NO332770B1 NO332770B1 (en) | 2013-01-14 |
Family
ID=32103878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052286A NO332770B1 (en) | 2002-10-11 | 2005-05-10 | Process for the recovery of a natural mixture of conjugated equine estrogens with a greatly reduced content of non-conjugated lipophilic compounds. |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1553959B1 (en) |
| JP (1) | JP4778233B2 (en) |
| CN (1) | CN100542542C (en) |
| AR (1) | AR041121A1 (en) |
| AT (1) | ATE427752T1 (en) |
| AU (1) | AU2003301237B2 (en) |
| BR (1) | BR0314639A (en) |
| CA (1) | CA2498095C (en) |
| DE (1) | DE50311398D1 (en) |
| DK (1) | DK1553959T3 (en) |
| ES (1) | ES2324533T3 (en) |
| HK (1) | HK1083450A1 (en) |
| IL (1) | IL167924A (en) |
| MX (1) | MXPA05003619A (en) |
| NO (1) | NO332770B1 (en) |
| PL (1) | PL205861B1 (en) |
| PT (1) | PT1553959E (en) |
| RU (1) | RU2329818C2 (en) |
| SI (1) | SI1553959T1 (en) |
| TW (1) | TWI284131B (en) |
| WO (1) | WO2004035067A1 (en) |
| ZA (1) | ZA200502494B (en) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2429398A (en) * | 1943-08-20 | 1947-10-21 | Ayerst Mckenna & Harrison | Hormone extracts |
| US2565115A (en) * | 1948-10-28 | 1951-08-21 | Squibb & Sons Inc | Method of obtaining a conjugated estrogen preparation |
| CA2140770A1 (en) * | 1992-08-05 | 1994-02-17 | Timothy A. Holton | Genetic sequences encoding flavonol synthase enzymes and uses therefor |
| HU228763B1 (en) * | 1996-08-30 | 2013-05-28 | Abbott Products Gmbh | Method to obtain oestrogens from mare's urine |
| DE19681616B4 (en) * | 1996-08-30 | 2006-03-09 | Solvay Pharmaceuticals Gmbh | Process for obtaining estrogens from mare urine |
| WO2001027134A1 (en) * | 1999-10-13 | 2001-04-19 | Scinopharm Singapore Pte Ltd. | Process for extracting estrogens from pregnant mare urine (pmu) |
| EA200301022A1 (en) * | 2001-03-16 | 2004-02-26 | Уайт | HORMONAL REPLACEMENT THERAPY |
-
2003
- 2003-09-01 AR ARP030103169A patent/AR041121A1/en unknown
- 2003-10-06 TW TW092127669A patent/TWI284131B/en not_active IP Right Cessation
- 2003-10-08 RU RU2005114481/15A patent/RU2329818C2/en not_active IP Right Cessation
- 2003-10-08 CA CA2498095A patent/CA2498095C/en not_active Expired - Fee Related
- 2003-10-08 JP JP2004544306A patent/JP4778233B2/en not_active Expired - Fee Related
- 2003-10-08 MX MXPA05003619A patent/MXPA05003619A/en active IP Right Grant
- 2003-10-08 SI SI200331580T patent/SI1553959T1/en unknown
- 2003-10-08 EP EP03808742A patent/EP1553959B1/en not_active Expired - Lifetime
- 2003-10-08 WO PCT/EP2003/050703 patent/WO2004035067A1/en active Application Filing
- 2003-10-08 CN CNB2003801006999A patent/CN100542542C/en not_active Expired - Fee Related
- 2003-10-08 DK DK03808742T patent/DK1553959T3/en active
- 2003-10-08 PL PL374684A patent/PL205861B1/en unknown
- 2003-10-08 AT AT03808742T patent/ATE427752T1/en active
- 2003-10-08 AU AU2003301237A patent/AU2003301237B2/en not_active Ceased
- 2003-10-08 BR BR0314639-1A patent/BR0314639A/en not_active Application Discontinuation
- 2003-10-08 PT PT03808742T patent/PT1553959E/en unknown
- 2003-10-08 DE DE50311398T patent/DE50311398D1/en not_active Expired - Lifetime
- 2003-10-08 ES ES03808742T patent/ES2324533T3/en not_active Expired - Lifetime
-
2005
- 2005-03-29 ZA ZA200502494A patent/ZA200502494B/en unknown
- 2005-04-07 IL IL167924A patent/IL167924A/en not_active IP Right Cessation
- 2005-05-10 NO NO20052286A patent/NO332770B1/en not_active IP Right Cessation
-
2006
- 2006-03-17 HK HK06103416.4A patent/HK1083450A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK1553959T3 (en) | 2009-06-08 |
| PT1553959E (en) | 2009-05-08 |
| EP1553959B1 (en) | 2009-04-08 |
| IL167924A (en) | 2010-05-31 |
| AR041121A1 (en) | 2005-05-04 |
| ATE427752T1 (en) | 2009-04-15 |
| RU2329818C2 (en) | 2008-07-27 |
| PL205861B1 (en) | 2010-06-30 |
| AU2003301237B2 (en) | 2009-09-17 |
| MXPA05003619A (en) | 2005-06-03 |
| JP4778233B2 (en) | 2011-09-21 |
| ES2324533T3 (en) | 2009-08-10 |
| CA2498095C (en) | 2014-12-16 |
| DE50311398D1 (en) | 2009-05-20 |
| JP2006505561A (en) | 2006-02-16 |
| BR0314639A (en) | 2005-08-02 |
| CA2498095A1 (en) | 2004-04-29 |
| PL374684A1 (en) | 2005-10-31 |
| RU2005114481A (en) | 2006-08-10 |
| EP1553959A1 (en) | 2005-07-20 |
| NO20052286D0 (en) | 2005-05-10 |
| TWI284131B (en) | 2007-07-21 |
| SI1553959T1 (en) | 2009-08-31 |
| CN100542542C (en) | 2009-09-23 |
| CN1691951A (en) | 2005-11-02 |
| ZA200502494B (en) | 2006-07-26 |
| WO2004035067A1 (en) | 2004-04-29 |
| TW200409779A (en) | 2004-06-16 |
| HK1083450A1 (en) | 2006-07-07 |
| NO332770B1 (en) | 2013-01-14 |
| AU2003301237A1 (en) | 2004-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |