NO20052009L - Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome - Google Patents
Combination therapy for the treatment of acute leukemia and myelodysplastic syndromeInfo
- Publication number
- NO20052009L NO20052009L NO20052009A NO20052009A NO20052009L NO 20052009 L NO20052009 L NO 20052009L NO 20052009 A NO20052009 A NO 20052009A NO 20052009 A NO20052009 A NO 20052009A NO 20052009 L NO20052009 L NO 20052009L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- myelodysplastic syndrome
- acute leukemia
- combination therapy
- pharmaceutical combinations
- Prior art date
Links
Classifications
-
- E—FIXED CONSTRUCTIONS
- E05—LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
- E05F—DEVICES FOR MOVING WINGS INTO OPEN OR CLOSED POSITION; CHECKS FOR WINGS; WING FITTINGS NOT OTHERWISE PROVIDED FOR, CONCERNED WITH THE FUNCTIONING OF THE WING
- E05F3/00—Closers or openers with braking devices, e.g. checks; Construction of pneumatic or liquid braking devices
- E05F3/04—Closers or openers with braking devices, e.g. checks; Construction of pneumatic or liquid braking devices with liquid piston brakes
- E05F3/10—Closers or openers with braking devices, e.g. checks; Construction of pneumatic or liquid braking devices with liquid piston brakes with a spring, other than a torsion spring, and a piston, the axes of which are the same or lie in the same direction
- E05F3/108—Closers or openers with braking devices, e.g. checks; Construction of pneumatic or liquid braking devices with liquid piston brakes with a spring, other than a torsion spring, and a piston, the axes of which are the same or lie in the same direction with piston rod protruding from the closer housing; Telescoping closers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- E—FIXED CONSTRUCTIONS
- E05—LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
- E05F—DEVICES FOR MOVING WINGS INTO OPEN OR CLOSED POSITION; CHECKS FOR WINGS; WING FITTINGS NOT OTHERWISE PROVIDED FOR, CONCERNED WITH THE FUNCTIONING OF THE WING
- E05F3/00—Closers or openers with braking devices, e.g. checks; Construction of pneumatic or liquid braking devices
Abstract
Det beskrives fremgangsmåter for behandling og farmasøytiske kombinasjoner for behandlingen av akutt leukemi, så som akutt myelogen leukemi og myelodysplastisk syndrom. Fremgangsmåtene og de farmasøytiske kombinasjonene benytter et anti-CD33 cytotoksisk konjugat i kombinasjon med minst én forbindelse valgt fra gruppen bestående av et antracyklin og en pyrimidin- eller purin-nukleosidanalog. Foretrukne fremgangsmåter for behandling og farmasøytiske kombinasjoner benytter gemtuzumab ozogamicin, daunorubicin og cytarabin.Methods of treatment and pharmaceutical combinations for the treatment of acute leukemia, such as acute myelogenous leukemia and myelodysplastic syndrome, are described. The methods and pharmaceutical combinations employ an anti-CD33 cytotoxic conjugate in combination with at least one compound selected from the group consisting of an anthracycline and a pyrimidine or purine nucleoside analogue. Preferred methods of treatment and pharmaceutical combinations utilize gemtuzumab ozogamicin, daunorubicin and cytarabine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2002/035532 WO2004043461A1 (en) | 2002-11-06 | 2002-11-06 | Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20052009D0 NO20052009D0 (en) | 2005-04-25 |
NO20052009L true NO20052009L (en) | 2005-06-27 |
Family
ID=32311637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20052009A NO20052009L (en) | 2002-11-06 | 2005-04-25 | Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1575582A4 (en) |
JP (1) | JP2006508119A (en) |
CN (1) | CN1720044A (en) |
AU (2) | AU2002348178A1 (en) |
BR (1) | BR0215935A (en) |
CA (1) | CA2504611A1 (en) |
CR (1) | CR7804A (en) |
MX (1) | MXPA05004711A (en) |
NO (1) | NO20052009L (en) |
WO (1) | WO2004043461A1 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7977320B2 (en) | 2004-10-29 | 2011-07-12 | The Regents Of The University Of California | Method of increasing efficacy of tumor cell killing using combinations of anti-neoplastic agents |
EP1661584A1 (en) * | 2004-11-26 | 2006-05-31 | Heinz Dr. Faulstich | Use of conjugates of amatoxins and phallotoxins with macromolecules for cancer and inflammation therapy |
CA2614321A1 (en) * | 2005-07-06 | 2007-01-18 | Kanisa Pharmaceuticals, Inc. | Treatment of patients with cancer using a calicheamicin-antibody conjugate in combination with zosuquidar |
ATE521366T1 (en) * | 2006-05-27 | 2011-09-15 | Faulstich Heinz Dr | APPLICATION OF AMATOXIN CONJUGATES AND PHALLOTOXIN CONJUGATES WITH MACROMOLECLES FOR CANCER THERAPY AND THERAPY OF INFLAMMATION |
CN1994293A (en) * | 2006-08-18 | 2007-07-11 | 上海交通大学医学院附属瑞金医院 | Application of oridonin in medicine preparation |
JP2010509234A (en) * | 2006-11-02 | 2010-03-25 | シアトル ジェネティックス, インコーポレイテッド | Methods for treating neoplastic diseases, autoimmune diseases and inflammatory diseases |
US20100303895A1 (en) * | 2007-02-16 | 2010-12-02 | Arthur Louie | Fixed drug ratios for treatment of hematopoietic cancers and proliferative disorders |
CA2708264C (en) | 2007-12-10 | 2018-07-03 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders |
JP5592793B2 (en) | 2008-08-29 | 2014-09-17 | 学校法人北里研究所 | Method for detecting drug effect of DNA methylation inhibitor |
WO2017160954A1 (en) | 2016-03-15 | 2017-09-21 | Seattle Genetics, Inc. | Combinations of pbd-based antibody drug conjugates with bcl-2 inhibitors |
EP3463463A4 (en) * | 2016-06-03 | 2020-01-15 | Seattle Genetics, Inc. | Combination of cd33 antibody drug conjugates with chemotherapeutic agents |
EP3469001A4 (en) | 2016-06-09 | 2020-05-06 | Seattle Genetics, Inc. | Combinations of pbd-based antibody drug conjugates with flt3 inhibitors |
BR112019026959A2 (en) * | 2017-06-22 | 2020-07-07 | Les Laboratoires Servier | combination of an mcl-1 inhibitor and standard treatment for haematological cancers, their uses and pharmaceutical compositions |
JP7305613B2 (en) * | 2017-07-09 | 2023-07-10 | バイオサイト リミテッド | Combination cancer therapy |
SG11202107906UA (en) * | 2019-01-28 | 2021-08-30 | Univ Texas | Metal chelator combination therapy for the treatment of cancer |
CN110123825B (en) * | 2019-05-28 | 2021-11-30 | 宁波市鄞州人民医院 | Pharmaceutical composition containing demethoxydaunorubicin |
JP2023548111A (en) * | 2020-10-27 | 2023-11-15 | ブイオーアール バイオファーマ インコーポレーテッド | Compositions and methods for treating hematopoietic malignancies |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5744460A (en) * | 1996-03-07 | 1998-04-28 | Novartis Corporation | Combination for treatment of proliferative diseases |
US20020103141A1 (en) * | 1998-12-23 | 2002-08-01 | Mckearn John P. | Antiangiogenic combination therapy for the treatment of cancer |
DK1309627T3 (en) * | 2000-08-08 | 2009-12-21 | Immunomedics Inc | Immunotherapy for chronic myelocytic leukemia with nude anti-NCA-90 antibody |
-
2002
- 2002-11-06 EP EP02784400A patent/EP1575582A4/en not_active Withdrawn
- 2002-11-06 JP JP2004551359A patent/JP2006508119A/en active Pending
- 2002-11-06 AU AU2002348178A patent/AU2002348178A1/en not_active Abandoned
- 2002-11-06 WO PCT/US2002/035532 patent/WO2004043461A1/en active Application Filing
- 2002-11-06 CN CNA028301404A patent/CN1720044A/en active Pending
- 2002-11-06 BR BR0215935-0A patent/BR0215935A/en not_active IP Right Cessation
- 2002-11-06 CA CA002504611A patent/CA2504611A1/en not_active Abandoned
- 2002-11-06 MX MXPA05004711A patent/MXPA05004711A/en active IP Right Grant
-
2005
- 2005-04-25 CR CR7804A patent/CR7804A/en not_active Application Discontinuation
- 2005-04-25 NO NO20052009A patent/NO20052009L/en not_active Application Discontinuation
-
2010
- 2010-03-22 AU AU2010201113A patent/AU2010201113A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1575582A1 (en) | 2005-09-21 |
WO2004043461A1 (en) | 2004-05-27 |
AU2010201113A1 (en) | 2010-04-15 |
NO20052009D0 (en) | 2005-04-25 |
AU2002348178A1 (en) | 2004-06-03 |
JP2006508119A (en) | 2006-03-09 |
CR7804A (en) | 2008-10-29 |
BR0215935A (en) | 2005-08-09 |
MXPA05004711A (en) | 2005-08-03 |
EP1575582A4 (en) | 2009-03-11 |
CA2504611A1 (en) | 2004-05-27 |
CN1720044A (en) | 2006-01-11 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |