NO20051461L - lnhaleringssammensetning - Google Patents
lnhaleringssammensetningInfo
- Publication number
- NO20051461L NO20051461L NO20051461A NO20051461A NO20051461L NO 20051461 L NO20051461 L NO 20051461L NO 20051461 A NO20051461 A NO 20051461A NO 20051461 A NO20051461 A NO 20051461A NO 20051461 L NO20051461 L NO 20051461L
- Authority
- NO
- Norway
- Prior art keywords
- microns
- diameter
- less
- lactose particles
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Otolaryngology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer en tørrpulverinhalereringssammensetning som innbefatter. medikamentpartikler og en blanding av laktosepartikler med en VMD på mellom ca. 70 og 120 mikron og en diameter på mindre enn 250 mikron, hvor blandingen er kjennetegnet ved at opp til 96 vekt-% av laktosepartiklene er mindre enn 150 mikron i diameter, og hvori opp til 25 vekt-% av laktosepartiklene er mindre enn 5 mikron i diameter. Sammensetningene tilveiebringer en mer nøyaktig, enhetlig og. konsistent dispersjon når den for eksempel anvendes med en multidose tørrpulveirnhalerer.Også beskrevet er fremgangsmåter for anvendelse av sammensetningene ifølge oppfinnelsen.The present invention provides a dry powder inhalation composition which includes. drug particles and a mixture of lactose particles with a VMD of between approx. 70 and 120 microns and a diameter of less than 250 microns, wherein the mixture is characterized in that up to 96% by weight of the lactose particles are less than 150 microns in diameter, and in which up to 25% by weight of the lactose particles are less than 5 microns. in diameter. The compositions provide a more accurate, uniform and. consistent dispersion when used, for example, with a multidose dry powder inhaler. Also described are methods of using the compositions of the invention.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0219513A GB0219513D0 (en) | 2002-08-21 | 2002-08-21 | Inhalation compositions including coarse carrier |
PCT/US2003/026385 WO2004017914A2 (en) | 2002-08-21 | 2003-08-21 | Inhalation composition |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20051461L true NO20051461L (en) | 2005-05-20 |
Family
ID=9942746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20051461A NO20051461L (en) | 2002-08-21 | 2005-03-18 | lnhaleringssammensetning |
Country Status (8)
Country | Link |
---|---|
BR (1) | BRPI0313647A2 (en) |
CA (1) | CA2499273C (en) |
ES (1) | ES2371601T3 (en) |
GB (1) | GB0219513D0 (en) |
NO (1) | NO20051461L (en) |
TN (1) | TNSN05047A1 (en) |
WO (1) | WO2004017914A2 (en) |
ZA (1) | ZA200502177B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005102429A1 (en) | 2004-04-21 | 2005-11-03 | Innovata Biomed Limited | Inhaler |
LT2708225T (en) | 2004-04-23 | 2019-04-10 | Cydex Pharmaceuticals, Inc. | DPI Formulation Containing Sulfoalkyl Ether Cyclodextrin |
GB0409197D0 (en) | 2004-04-24 | 2004-05-26 | Innovata Biomed Ltd | Device |
CN104177448A (en) | 2005-02-10 | 2014-12-03 | 葛兰素集团有限公司 | Processes For Making Lactose Utilizing Pre-Classification Techniques And Pharmaceutical Formulations Formed Therefrom |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
GB0605723D0 (en) * | 2006-03-23 | 2006-05-03 | 3M Innovative Properties Co | Powder filling processes |
WO2008134817A1 (en) * | 2007-05-03 | 2008-11-13 | The University Of Sydney | Composite carriers for dry powder inhalation therapy |
TR201105367A2 (en) * | 2011-06-02 | 2012-12-21 | Bi̇lgi̇ç Mahmut | A dry powder formulation with improved flow properties. |
TR201205852A2 (en) * | 2011-06-02 | 2012-12-21 | Bi̇lgi̇ç Mahmut | Improved new dry powder formulation. |
GEP201706672B (en) | 2012-07-05 | 2017-05-25 | Arven Ilac Sanayi Ve Ticaret As | Dry powder inhaler compositions comprising long acting muscorinic antagonists |
EP2874928B1 (en) | 2012-07-19 | 2016-06-15 | Adamis Pharmaceuticals Corporation | Powder feeding apparatus |
JP6251667B2 (en) | 2014-06-03 | 2017-12-20 | アサヒカルピスウェルネス株式会社 | Tablet-type immediate release preparation and method for producing the same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2347856C (en) * | 1998-11-13 | 2009-02-17 | Jago Research Ag | Dry powder for inhalation |
JP2002532405A (en) * | 1998-12-11 | 2002-10-02 | ファルマヘミー ベー.フェー. | Opioid inhalation preparation |
AU757008B2 (en) | 2000-10-12 | 2003-01-30 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel tiotropium-containing inhalation powder |
UA75375C2 (en) | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
-
2002
- 2002-08-21 GB GB0219513A patent/GB0219513D0/en not_active Ceased
-
2003
- 2003-08-21 WO PCT/US2003/026385 patent/WO2004017914A2/en active Application Filing
- 2003-08-21 BR BRPI0313647A patent/BRPI0313647A2/en active Search and Examination
- 2003-08-21 ES ES03751884T patent/ES2371601T3/en not_active Expired - Lifetime
- 2003-08-21 CA CA2499273A patent/CA2499273C/en not_active Expired - Fee Related
-
2005
- 2005-02-18 TN TNP2005000047A patent/TNSN05047A1/en unknown
- 2005-03-15 ZA ZA200502177A patent/ZA200502177B/en unknown
- 2005-03-18 NO NO20051461A patent/NO20051461L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2004017914A8 (en) | 2005-07-07 |
WO2004017914A3 (en) | 2004-04-29 |
BRPI0313647A2 (en) | 2019-02-19 |
WO2004017914A2 (en) | 2004-03-04 |
CA2499273C (en) | 2011-06-21 |
ES2371601T3 (en) | 2012-01-05 |
ZA200502177B (en) | 2006-05-31 |
CA2499273A1 (en) | 2004-03-04 |
TNSN05047A1 (en) | 2007-05-14 |
GB0219513D0 (en) | 2002-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application | ||
RE | Reestablishment of rights (par. 72 patents act) | ||
FC2A | Withdrawal, rejection or dismissal of laid open patent application |