NO20022971L - Butynediol derivatives - Google Patents
Butynediol derivativesInfo
- Publication number
- NO20022971L NO20022971L NO20022971A NO20022971A NO20022971L NO 20022971 L NO20022971 L NO 20022971L NO 20022971 A NO20022971 A NO 20022971A NO 20022971 A NO20022971 A NO 20022971A NO 20022971 L NO20022971 L NO 20022971L
- Authority
- NO
- Norway
- Prior art keywords
- butynediol
- derivatives
- compounds
- preparation
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Abstract
Foreliggende oppfinnelse angår nye butyndiol-derivater med den generelle formel I og anvendelse av dem som aktive bestanddeler ved fremstilling av farmasøytiske preparater. Oppfinnelsen angår også beslektede aspekter omfattende fremgangsmåter for fremstilling av forbindelsene, farmasøytiske preparater inneholdende én eller flere forbindelser med den generelle formel I og spesielt anvendelse av dem som endotelin-reseptorantagonister.The present invention relates to novel butynediol derivatives of the general formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also relates to related aspects comprising processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of the general formula I and in particular their use as endothelin receptor antagonists.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP9910276 | 1999-12-22 | ||
PCT/EP2000/012743 WO2001046156A1 (en) | 1999-12-22 | 2000-12-14 | Butyne diol derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20022971L true NO20022971L (en) | 2002-06-20 |
NO20022971D0 NO20022971D0 (en) | 2002-06-20 |
Family
ID=8167542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20022971A NO20022971D0 (en) | 1999-12-22 | 2002-06-20 | Butynediol derivatives |
Country Status (12)
Country | Link |
---|---|
JP (1) | JP2003518102A (en) |
KR (1) | KR20020068373A (en) |
CN (1) | CN1407973A (en) |
AU (1) | AU3536701A (en) |
BR (1) | BR0016241A (en) |
CA (1) | CA2389479A1 (en) |
HU (1) | HUP0204168A2 (en) |
IL (1) | IL149529A0 (en) |
MX (1) | MXPA02006250A (en) |
NO (1) | NO20022971D0 (en) |
WO (1) | WO2001046156A1 (en) |
ZA (1) | ZA200203796B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001263850A1 (en) * | 2000-04-20 | 2001-11-07 | Actelion Pharmaceuticals Ltd | Pyrimidine-sulfonamides having endothelin-antagonist activity |
BRPI0116237B8 (en) | 2000-12-18 | 2021-05-25 | Actelion Pharmaceuticals Ltd | "sulfamide compound, pharmaceutical composition containing it and its use as an endothelin receptor antagonist drug". |
DE602005021641D1 (en) | 2004-06-08 | 2010-07-15 | Nsab, Filial Af Neurosearch Sweden Ab | NEW DISUBSTITUTED PHENYLPIPERIDINES AND PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION |
AR062501A1 (en) | 2006-08-29 | 2008-11-12 | Actelion Pharmaceuticals Ltd | THERAPEUTIC COMPOSITIONS |
MX2010001837A (en) | 2007-08-17 | 2010-03-10 | Actelion Pharmaceuticals Ltd | Iron with actively cooled soleplate and method for cooling the soleplate. |
US8916385B2 (en) * | 2007-12-13 | 2014-12-23 | Quest Diagnostics Investments, Inc. | Methods for detecting estrone by mass spectrometry |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2086544C1 (en) * | 1991-06-13 | 1997-08-10 | Хоффманн-Ля Рош АГ | Benzenesulfonamide derivatives of pyrimidine or their salts, pharmaceutical composition for treatment of diseases associated with endothelin activity |
CA2162630C (en) * | 1994-11-25 | 2007-05-01 | Volker Breu | Sulfonamides |
TW313568B (en) * | 1994-12-20 | 1997-08-21 | Hoffmann La Roche | |
HUT77307A (en) * | 1994-12-20 | 1998-03-30 | F. Hoffmann-La Roche Ag. | Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antagonists |
US5739333A (en) * | 1995-05-16 | 1998-04-14 | Tanabe Seiyaku Co., Ltd. | Sulfonamide derivative and process for preparing the same |
CZ260596A3 (en) * | 1995-10-12 | 1997-12-17 | Hoffmann La Roche | Sulfonamide derivative, process of its preparation and pharmaceutical composition containing thereof |
HUP0000474A3 (en) * | 1995-12-20 | 2001-06-28 | Astellas Pharma Inc Chuo Ku | Arylethenesulfonamide derivatives and drug composition containing the same |
WO1998003488A1 (en) * | 1996-07-23 | 1998-01-29 | Shionogi & Co., Ltd. | Novel pyrimidine compounds and drug compositions |
AU1785599A (en) * | 1998-01-19 | 1999-08-02 | Shionogi & Co., Ltd. | Novel pyrimidine derivatives |
-
2000
- 2000-12-14 MX MXPA02006250A patent/MXPA02006250A/en unknown
- 2000-12-14 AU AU35367/01A patent/AU3536701A/en not_active Abandoned
- 2000-12-14 CN CN00816718A patent/CN1407973A/en active Pending
- 2000-12-14 CA CA002389479A patent/CA2389479A1/en not_active Abandoned
- 2000-12-14 IL IL14952900A patent/IL149529A0/en unknown
- 2000-12-14 BR BR0016241-8A patent/BR0016241A/en not_active Application Discontinuation
- 2000-12-14 KR KR1020027007566A patent/KR20020068373A/en not_active Application Discontinuation
- 2000-12-14 JP JP2001547067A patent/JP2003518102A/en active Pending
- 2000-12-14 HU HU0204168A patent/HUP0204168A2/en unknown
- 2000-12-14 WO PCT/EP2000/012743 patent/WO2001046156A1/en not_active Application Discontinuation
-
2002
- 2002-05-13 ZA ZA200203796A patent/ZA200203796B/en unknown
- 2002-06-20 NO NO20022971A patent/NO20022971D0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20020068373A (en) | 2002-08-27 |
BR0016241A (en) | 2002-11-12 |
IL149529A0 (en) | 2002-11-10 |
MXPA02006250A (en) | 2004-09-06 |
ZA200203796B (en) | 2003-10-29 |
HUP0204168A2 (en) | 2003-04-28 |
NO20022971D0 (en) | 2002-06-20 |
AU3536701A (en) | 2001-07-03 |
WO2001046156A1 (en) | 2001-06-28 |
CA2389479A1 (en) | 2001-06-28 |
CN1407973A (en) | 2003-04-02 |
JP2003518102A (en) | 2003-06-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20050932L (en) | 1-pyridin-4-yl-urea derivatives | |
ATE286500T1 (en) | 1,2,3,4-TETRAHYDROISOCINOLINE DERIVATIVES | |
NO20061395L (en) | New pyridine derivatives | |
NO20032905L (en) | New benzodiazepines and related heterocyclic derivatives useful as orexin receptor antagonists | |
NO20051102L (en) | Sulfonylamino-acetic acid derivatives | |
NO20042844L (en) | 4- (piperidyl- and pyrrolidyl-alkyl-ureido) -quinolines as uprotensin II receptor antagonists | |
MXPA03004780A (en) | Novel sulfamides and their use as endothelin receptor antagonists. | |
MXPA05010137A (en) | Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists. | |
NO20034230L (en) | 1,2,3,4-tetrahydroisoquinoline derivatives as urotensin II receptor antagonists | |
NO20050668L (en) | 7,8,9,10-tetrahydro-6H-azepino6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2H-pyrrolo [2,1-B] quinazolinone derivatives | |
NO20050290L (en) | Novel tetrahydropyridine derivatives as renin inhibitors | |
ECSP045378A (en) | NEW DIAZABICICLONONENE DERIVATIVES | |
NO20052520L (en) | New sulfamides | |
ATE383345T1 (en) | QUINOXALIN-3-ONE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS. | |
MXPA04001252A (en) | Novel benzo-fused heterocycles as endothelin antagonisits. | |
WO2002024665A8 (en) | Arylalkane-sulfonamides having endothelin-antagonist activity | |
DK1307445T3 (en) | Benzofuran derivatives and their use as antibacterial agents | |
WO2002008200A3 (en) | Arylethene-sulfonamides, their preparation and their use as endothelin antagonists | |
NO20022971L (en) | Butynediol derivatives | |
DE602004027384D1 (en) | BENZOFURANDERIVATES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |