NO20021949D0 - New hormone preparations and their use - Google Patents

New hormone preparations and their use

Info

Publication number
NO20021949D0
NO20021949D0 NO20021949A NO20021949A NO20021949D0 NO 20021949 D0 NO20021949 D0 NO 20021949D0 NO 20021949 A NO20021949 A NO 20021949A NO 20021949 A NO20021949 A NO 20021949A NO 20021949 D0 NO20021949 D0 NO 20021949D0
Authority
NO
Norway
Prior art keywords
hormone preparations
new hormone
esters
menopausal women
new
Prior art date
Application number
NO20021949A
Other languages
Norwegian (no)
Other versions
NO20021949L (en
NO327973B1 (en
Inventor
Jacques Paris
Jean-Louis Thomas
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Publication of NO20021949L publication Critical patent/NO20021949L/en
Publication of NO20021949D0 publication Critical patent/NO20021949D0/en
Publication of NO327973B1 publication Critical patent/NO327973B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

A method of preventing estrogen deficiencies and osteoporosis in menopausal women by continuously orally administering without interruption to menopausal women in need thereof an amount of 0.3 to 3 mg of 17beta-estradiol or esters thereof and 0.3 to 1.25 mg of nomegestrol or esters thereof in an amount sufficient to prevent said problems.
NO20021949A 1999-10-25 2002-04-25 Use of a combined oestroprogestative compound for the manufacture of a drug for the correction of oestrogenic disorders in women and prevention of osteoporosis and cardiovascular diseases in women of menopause NO327973B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/FR1999/002588 WO2001030356A1 (en) 1999-10-25 1999-10-25 Hormonal composition based on a progestational agent and an oestrogen and use thereof
PCT/FR2000/002939 WO2001030357A1 (en) 1999-10-25 2000-10-24 Hormonal composition based on a progesterone and an oestrogen and use thereof

Publications (3)

Publication Number Publication Date
NO20021949L NO20021949L (en) 2002-04-25
NO20021949D0 true NO20021949D0 (en) 2002-04-25
NO327973B1 NO327973B1 (en) 2009-11-02

Family

ID=9542727

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021949A NO327973B1 (en) 1999-10-25 2002-04-25 Use of a combined oestroprogestative compound for the manufacture of a drug for the correction of oestrogenic disorders in women and prevention of osteoporosis and cardiovascular diseases in women of menopause

Country Status (27)

Country Link
US (2) US8168619B1 (en)
EP (1) EP1227814B1 (en)
JP (1) JP5036943B2 (en)
KR (1) KR100623788B1 (en)
CN (1) CN100553637C (en)
AP (1) AP1625A (en)
AT (1) ATE286400T1 (en)
AU (1) AU777704B2 (en)
BR (1) BRPI0014979B8 (en)
CA (1) CA2389025C (en)
CZ (1) CZ303248B6 (en)
DE (1) DE60017281T2 (en)
DK (1) DK1227814T3 (en)
ES (1) ES2235967T3 (en)
HK (1) HK1050472B (en)
HU (1) HU229382B1 (en)
IL (2) IL148953A0 (en)
MX (1) MXPA02004084A (en)
NO (1) NO327973B1 (en)
NZ (1) NZ518145A (en)
OA (1) OA12072A (en)
PL (1) PL199848B1 (en)
PT (1) PT1227814E (en)
RU (1) RU2261106C2 (en)
SI (1) SI1227814T1 (en)
WO (2) WO2001030356A1 (en)
ZA (1) ZA200203398B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754179B1 (en) 1996-10-08 1998-12-24 Theramex NOVEL HORMONONAL COMPOSITION AND ITS USE
WO2001030356A1 (en) 1999-10-25 2001-05-03 Laboratoire Theramex Hormonal composition based on a progestational agent and an oestrogen and use thereof
FR2814074B1 (en) * 2000-09-15 2003-03-07 Theramex NOVEL TOPICAL ESTRO-PROGESTIVE COMPOSITIONS WITH SYSTEMIC EFFECT
US8048869B2 (en) 2001-05-18 2011-11-01 Pantarhei Bioscience B.V. Pharmaceutical composition for use in hormone replacement therapy
EP1390042B1 (en) 2001-05-23 2007-11-28 Pantarhei Bioscience B.V. Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
CA2448273C (en) 2001-05-23 2010-06-29 Christian Franz Holinka Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
DK1446128T3 (en) 2001-11-15 2007-04-02 Pantarhei Bioscience Bv Use of estrogen compounds in combination with progestogen compounds in hormone replacement therapy
US7943604B2 (en) 2002-06-11 2011-05-17 Pantarhei Bioscience B.V. Method of treating human skin and a skin care composition for use in such a method
PT1511496E (en) 2002-06-11 2007-01-31 Pantarhei Bioscience Bv Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein
EP1515725A4 (en) * 2002-06-25 2005-09-21 Wyeth Corp Use of cyclothiocarbamate derivatives in treatment of hormone-related conditions
DK1526856T3 (en) 2002-07-12 2008-03-10 Pantarhei Bioscience Bv Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
DK1556058T3 (en) 2002-10-23 2008-03-03 Pantarhei Bioscience Bv Pharmaceutical compositions comprising oestetrol derivatives for use in cancer therapy
EP2114412B1 (en) 2007-01-08 2010-07-14 Pantarhei Bioscience B.V. Method of treating or preventing infertility in a female mammal and pharmaceutical kit for use in such method
CN107007611B (en) * 2017-06-02 2020-04-14 上海市计划生育科学研究所 Application of nomegestrol acetate in preparation of medicine for treating endometrial cancer

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
JPS61243059A (en) 1985-04-19 1986-10-29 Konishi Kagaku Kogyo Kk Production of high-purity 4-4'-dihydroxydiphenyl-sulfone
DE3603644A1 (en) 1986-02-06 1987-08-13 Metabowerke Kg CHUCK FOR CLAMPING DRILLS OR IMPACT DRILLS
US5208225A (en) * 1986-02-27 1993-05-04 Warner-Lambert Company Compositions containing fixed combinations
ZA87332B (en) 1986-02-27 1987-08-26 Warner Lambert Co Compositions containing fixed combinations
US5256421A (en) 1987-09-24 1993-10-26 Jencap Research Ltd. Hormone preparation and method
CA1332227C (en) 1987-09-24 1994-10-04 Robert F. Casper Oral contraceptive formulation
US5276022A (en) 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
NO301689B1 (en) 1987-09-24 1997-12-01 Jencap Research Ltd Contraceptive preparation in the form of a package
US5108995A (en) 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
HUT52382A (en) 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
IE71203B1 (en) 1990-12-13 1997-02-12 Akzo Nv Low estrogen oral contraceptives
FR2695826B1 (en) 1992-09-21 1995-01-06 Theramex New pharmaceutical compositions based on nomegestrol derivatives and methods for obtaining them.
US5554601A (en) 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
US5552394A (en) 1994-07-22 1996-09-03 The Medical College Of Hampton Roads Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
US6613757B1 (en) 1994-09-22 2003-09-02 Board Of Regents, The University Of Texas System Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy
SE9403389D0 (en) 1994-10-06 1994-10-06 Astra Ab Pharmaceutical composition containing derivatives of sex hormones
JPH11511128A (en) 1995-08-01 1999-09-28 ノバルティス・アクチエンゲゼルシャフト Liposome oligonucleotide composition
FR2737411B1 (en) 1995-08-01 1997-10-17 Theramex NOVEL HORMONAL DRUGS AND THEIR USE FOR CORRECTING ESTROGENIC DEFICIENCIES
US5888543A (en) 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
WO2001030355A1 (en) 1999-10-25 2001-05-03 Laboratoire Theramex Contraceptive medicine based on a progestational agent and an oestrogen and preparation method
FR2754179B1 (en) 1996-10-08 1998-12-24 Theramex NOVEL HORMONONAL COMPOSITION AND ITS USE
DE19739916C2 (en) 1997-09-11 2001-09-13 Hesch Rolf Dieter Use of a combination of a progestogen and an estrogen for the continuous inhibition of ovulation and possibly simultaneous treatment and / or prophylaxis of tumors of the mammary glands
FR2776191B1 (en) * 1998-03-23 2002-05-31 Theramex TOPICAL HORMONAL COMPOSITION WITH SYSTEMIC EFFECT
WO2001030356A1 (en) 1999-10-25 2001-05-03 Laboratoire Theramex Hormonal composition based on a progestational agent and an oestrogen and use thereof
FR2814074B1 (en) * 2000-09-15 2003-03-07 Theramex NOVEL TOPICAL ESTRO-PROGESTIVE COMPOSITIONS WITH SYSTEMIC EFFECT
DE60218881T2 (en) * 2001-11-15 2007-12-20 Pantarhei Bioscience B.V. METHOD FOR PREVENTING OR TREATING BENIGNEN GYNECOLOGICAL DISORDER
PE20081895A1 (en) 2007-03-26 2009-01-26 Theramex ORAL CONTRACEPTIVE REGIME

Also Published As

Publication number Publication date
EP1227814A1 (en) 2002-08-07
OA12072A (en) 2006-05-04
EP1227814B1 (en) 2005-01-05
HK1050472B (en) 2005-07-08
KR20020057979A (en) 2002-07-12
US8168619B1 (en) 2012-05-01
MXPA02004084A (en) 2003-08-20
HUP0203721A3 (en) 2003-07-28
CN1382053A (en) 2002-11-27
US9084796B2 (en) 2015-07-21
RU2002113652A (en) 2004-03-27
AP1625A (en) 2006-07-04
US20130172300A1 (en) 2013-07-04
NO20021949L (en) 2002-04-25
ATE286400T1 (en) 2005-01-15
PT1227814E (en) 2005-05-31
HK1050472A1 (en) 2003-06-27
CZ20021427A3 (en) 2002-08-14
BRPI0014979B1 (en) 2016-08-02
DE60017281D1 (en) 2005-02-10
NO327973B1 (en) 2009-11-02
AP2002002475A0 (en) 2002-06-30
AU1032601A (en) 2001-05-08
PL199848B1 (en) 2008-11-28
KR100623788B1 (en) 2006-09-18
HUP0203721A2 (en) 2003-03-28
WO2001030356A1 (en) 2001-05-03
ZA200203398B (en) 2003-12-03
AU777704B2 (en) 2004-10-28
CN100553637C (en) 2009-10-28
JP5036943B2 (en) 2012-09-26
PL356847A1 (en) 2004-07-12
BR0014979A (en) 2002-11-26
CA2389025A1 (en) 2001-05-03
BRPI0014979B8 (en) 2021-05-25
DE60017281T2 (en) 2005-12-08
IL148953A0 (en) 2002-11-10
ES2235967T3 (en) 2005-07-16
HU229382B1 (en) 2013-11-28
CA2389025C (en) 2009-12-08
RU2261106C2 (en) 2005-09-27
SI1227814T1 (en) 2005-06-30
JP2003515531A (en) 2003-05-07
WO2001030357A1 (en) 2001-05-03
NZ518145A (en) 2005-01-28
DK1227814T3 (en) 2005-04-11
IL148953A (en) 2007-06-03
CZ303248B6 (en) 2012-06-20

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees