NO174929C - Process for the preparation of a readily soluble concentrate of thrombin coagulable proteins - Google Patents

Process for the preparation of a readily soluble concentrate of thrombin coagulable proteins

Info

Publication number
NO174929C
NO174929C NO883342A NO883342A NO174929C NO 174929 C NO174929 C NO 174929C NO 883342 A NO883342 A NO 883342A NO 883342 A NO883342 A NO 883342A NO 174929 C NO174929 C NO 174929C
Authority
NO
Norway
Prior art keywords
thrombin
preparation
readily soluble
soluble concentrate
coagulable proteins
Prior art date
Application number
NO883342A
Other languages
Norwegian (no)
Other versions
NO883342D0 (en
NO174929B (en
NO883342L (en
Inventor
Myriana Burnouf
Thierry Burnouf
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of NO883342D0 publication Critical patent/NO883342D0/en
Publication of NO883342L publication Critical patent/NO883342L/en
Publication of NO174929B publication Critical patent/NO174929B/en
Publication of NO174929C publication Critical patent/NO174929C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Concentrate of thrombin-coagulable proteins, possessing a fibrinogen content of more than 70% and a sufficient amount of endogeneous factor XIII. It can be solubilised at room temperature. Its preparation involves at least one step of precipitation in the cold state with dilute ethanol and employs whole plasma as the starting material. the concentrate makes it possible, in particular, to obtain an injectable fibrinogen and a biological glue. <IMAGE>
NO883342A 1987-07-30 1988-07-28 Process for the preparation of a readily soluble concentrate of thrombin coagulable proteins NO174929C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8710798A FR2618784B1 (en) 1987-07-30 1987-07-30 CONCENTRATE OF THROMBIN-COAGULABLE PROTEINS, PROCESS FOR OBTAINING SAME AND ITS USE AS A BIOLOGICAL GLUE

Publications (4)

Publication Number Publication Date
NO883342D0 NO883342D0 (en) 1988-07-28
NO883342L NO883342L (en) 1989-01-31
NO174929B NO174929B (en) 1994-04-25
NO174929C true NO174929C (en) 1994-08-03

Family

ID=9353711

Family Applications (1)

Application Number Title Priority Date Filing Date
NO883342A NO174929C (en) 1987-07-30 1988-07-28 Process for the preparation of a readily soluble concentrate of thrombin coagulable proteins

Country Status (10)

Country Link
EP (1) EP0305243B1 (en)
JP (1) JP2787317B2 (en)
AT (1) ATE73341T1 (en)
CA (1) CA1341376C (en)
DE (1) DE3869018D1 (en)
DK (1) DK173568B1 (en)
ES (1) ES2039666T3 (en)
FR (1) FR2618784B1 (en)
GR (1) GR3004047T3 (en)
NO (1) NO174929C (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0431072Y2 (en) * 1988-03-14 1992-07-27
FR2639958B1 (en) * 1988-12-06 1992-08-21 Lille Transfusion Sanguine BIOLOGICAL SUPPORT FOR CELL CULTURES CONSISTING OF PLASMATIC PROTEINS COAGULATED BY THROMBIN, ITS USE FOR THE CULTURE OF KERATINOCYTES, THEIR RECOVERY AND THEIR TRANSPORT FOR THERAPEUTIC USE
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US7196054B1 (en) 1990-11-27 2007-03-27 The American National Red Cross Methods for treating wound tissue and forming a supplemented fibrin matrix
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
DE4202667C1 (en) * 1992-01-29 1993-05-13 Behringwerke Ag, 3550 Marburg, De
WO1994002183A1 (en) * 1992-07-27 1994-02-03 Haemacure Biotech Inc. Biocompatible surgical implant
FR2696095B1 (en) * 1992-09-30 1994-11-25 Inoteb Biological glue based on proteins coagulable by thrombin, enriched in platelet factors, its preparation and its application.
US5290918A (en) * 1993-02-23 1994-03-01 Haemacure Biotech Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by acidic precipitation
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
DK0835667T3 (en) 1996-03-15 2005-12-05 Chemo Sero Therapeut Res Inst Tissue adhesive suitable for spray application
WO1998055140A1 (en) * 1997-06-05 1998-12-10 Omrix Biopharmaceuticals S.A. Fibrinogen concentrate from human plasma
GB0216001D0 (en) 2002-07-10 2002-08-21 Nat Blood Authority Process and composition
US20060019234A1 (en) * 2004-07-22 2006-01-26 Shanbrom Technologies, Llc Modern blood banking employing improved cell preservation composition
FR2887883B1 (en) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement PROCESS FOR SEPARATING FIBRINOGEN PROTEINS, FACTOR XIII AND BIOLOGICAL GLUE OF SOLUBILIZED PLASMA FRONTION AND PREPARATION OF LYOPHILIZED CONCENTRATES OF SAID PROTEINS
FR2894831B1 (en) 2005-12-16 2008-02-15 Lab Francais Du Fractionnement THROMBIN FREE BIOLOGICAL GLUE AND USE THEREOF AS MEDICAMENT.
FR2952641B1 (en) 2009-11-18 2012-01-13 Lfb Biomedicaments PROCESS FOR TREATING BLOOD PLASMA COMPRISING A DISPERSION WASH STEP
FR3032621A1 (en) 2015-02-13 2016-08-19 Lab Francais Du Fractionnement BIOLOGICAL GLUE AND ITS USE AS MEDICINE
EP3307237A1 (en) 2015-06-12 2018-04-18 Laboratoire Français du Fractionnement et des Biotechnologies Injectable composition of factor vii and fillers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4156681A (en) * 1974-03-28 1979-05-29 Plasmesco Ag Process for isolating albumin from blood
AT359652B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
AT359653B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
EP0068048B1 (en) * 1981-06-25 1985-06-19 Serapharm GmbH &amp; Co. KG Enriched plasma derivative for promoting wound sealing and wound covering
US4374061A (en) * 1981-07-27 1983-02-15 Center For Blood Research, Inc. Means and methods for purifying Clq, Clr and Cls
DE3203775A1 (en) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg FIBRINOGEN PREPARATION, METHOD FOR THEIR PRODUCTION AND THEIR USE
DE3228502A1 (en) * 1982-07-30 1984-02-02 Behringwerke Ag, 3550 Marburg METHOD FOR PRODUCING THE C1 INACTIVATOR AND ITS USE
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
AT389815B (en) * 1984-03-09 1990-02-12 Immuno Ag METHOD FOR INACTIVATING VARIABLE FILTERABLE DISEASERS IN BLOOD PRODUCTS
US4613501A (en) * 1984-12-21 1986-09-23 New York Blood Center, Inc. Inactivation of viruses in labile blood derivatives

Also Published As

Publication number Publication date
NO883342D0 (en) 1988-07-28
CA1341376C (en) 2002-07-16
GR3004047T3 (en) 1993-03-31
ES2039666T3 (en) 1993-10-01
FR2618784B1 (en) 1990-04-06
DE3869018D1 (en) 1992-04-16
JPH02114A (en) 1990-01-05
DK424188A (en) 1989-01-31
EP0305243A1 (en) 1989-03-01
EP0305243B1 (en) 1992-03-11
JP2787317B2 (en) 1998-08-13
FR2618784A1 (en) 1989-02-03
DK424188D0 (en) 1988-07-29
NO174929B (en) 1994-04-25
NO883342L (en) 1989-01-31
ATE73341T1 (en) 1992-03-15
DK173568B1 (en) 2001-03-19

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