NO173237C - CHEMILUMINIZING ACRIDINE DERIVATIVES - Google Patents
CHEMILUMINIZING ACRIDINE DERIVATIVESInfo
- Publication number
- NO173237C NO173237C NO890689A NO890689A NO173237C NO 173237 C NO173237 C NO 173237C NO 890689 A NO890689 A NO 890689A NO 890689 A NO890689 A NO 890689A NO 173237 C NO173237 C NO 173237C
- Authority
- NO
- Norway
- Prior art keywords
- chemiluminizing
- acridine derivatives
- formula
- image
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B15/00—Acridine dyes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Luminescent Compositions (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Paints Or Removers (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pyridine Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Chemiluminescent acridinium derivatives of the formula I <IMAGE> in which R<4> is a radical of the formula II or III <IMAGE> and A<(-)>, X-, R<1>-R<3>, R<5> and R<6> have the specified meanings, and processes for the preparation of the compounds of the formula (I) and the use thereof in chemiluminescence immunoassays.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO923800A NO303657B1 (en) | 1988-02-20 | 1992-09-30 | Method for Preparing a Luminescent Compound and Using the Compound Made in a Luminescence Immunoassay to Determine an Antigenic Substance in a Liquid Specimen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19883805318 DE3805318C2 (en) | 1988-02-20 | 1988-02-20 | Special chemiluminescent acridine derivatives and their use in luminescent immunoassays |
Publications (4)
Publication Number | Publication Date |
---|---|
NO890689D0 NO890689D0 (en) | 1989-02-17 |
NO890689L NO890689L (en) | 1989-08-21 |
NO173237B NO173237B (en) | 1993-08-09 |
NO173237C true NO173237C (en) | 1993-11-17 |
Family
ID=6347802
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO890689A NO173237C (en) | 1988-02-20 | 1989-02-17 | CHEMILUMINIZING ACRIDINE DERIVATIVES |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0330050B1 (en) |
JP (1) | JP2602315B2 (en) |
AT (1) | ATE195757T1 (en) |
CA (1) | CA1339390C (en) |
DE (2) | DE3844954C2 (en) |
DK (1) | DK175493B1 (en) |
ES (1) | ES2151474T3 (en) |
FI (1) | FI90537C (en) |
GR (1) | GR3034888T3 (en) |
NO (1) | NO173237C (en) |
PT (1) | PT89759B (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5110932A (en) * | 1986-10-06 | 1992-05-05 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
EP0273115B1 (en) * | 1986-10-22 | 1994-09-07 | Abbott Laboratories | Chemiluminescent acridinium and phenanthridinium salts |
US5338847A (en) * | 1987-12-31 | 1994-08-16 | London Diagnostics, Inc. | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation |
US5321136A (en) * | 1987-12-31 | 1994-06-14 | London Diagnostics, Inc. | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom |
US5283334A (en) * | 1987-12-31 | 1994-02-01 | London Diagnostics, Inc. | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom |
US5227489A (en) * | 1988-08-01 | 1993-07-13 | Ciba Corning Diagnostics Corp. | Stable hydrophilic acridinium esters suitable for liposome encapsulation |
US5241070A (en) * | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
US5663074A (en) * | 1988-09-26 | 1997-09-02 | Chiron Diagnostics Corporation | Nucleophilic polysubstituted aryl acridinium ester conjugates and syntheses thereof |
EP0511366A1 (en) * | 1990-11-21 | 1992-11-04 | Beckman Instruments, Inc. | Chemiluminescent compounds |
DE4041080A1 (en) | 1990-12-21 | 1992-06-25 | Behringwerke Ag | METHOD FOR DETERMINING AN ANALYT |
EP0522677B1 (en) * | 1991-07-10 | 1996-12-18 | TDK Corporation | Method of measuring concentration of immunoreactant using electrochemiluminescence |
DE4228839A1 (en) | 1992-08-29 | 1994-03-03 | Behringwerke Ag | Methods for the detection and determination of mediators |
JP3207933B2 (en) * | 1992-09-09 | 2001-09-10 | 株式会社ヤトロン | Light emission method of acridinium derivative and method of detecting target substance using the same |
BE1008216A4 (en) * | 1994-01-25 | 1996-02-20 | Biocode Sa | HETEROCYCLIC CHEMOLUMINESCENT DERIVATIVES. |
WO1996000284A1 (en) * | 1994-06-24 | 1996-01-04 | Behringwerke Aktiengesellschaft | Method of stabilizing molecules, or parts of molecules, which are sensitive to hydrolysis |
US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
EP0761652A1 (en) * | 1995-08-01 | 1997-03-12 | Mochida Pharmaceutical Co., Ltd. | Acridinium compound having a plurality of luminescent groups and binding groups, and conjugate thereof |
EP1019379B1 (en) * | 1997-08-21 | 2005-10-19 | Maine Medical Center | Peroxide-based chemiluminescent assays and chemiluminescent compounds used therein |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3352791A (en) * | 1965-01-22 | 1967-11-14 | American Cyanamid Co | Generation of light by the reaction of peroxide with heterocyclic derivatives |
FR2043486B1 (en) * | 1969-05-28 | 1973-07-13 | Roussel Uclaf | |
GB1461877A (en) * | 1974-02-12 | 1977-01-19 | Wellcome Found | Assay method utilizing chemiluminescence |
IN142734B (en) * | 1975-04-28 | 1977-08-20 | Miles Lab | |
GB2008247B (en) * | 1977-11-17 | 1982-12-15 | Welsh Nat School Med | Detecting or quantifying substances using labelling techniques |
US4334069A (en) * | 1978-07-24 | 1982-06-08 | Miles Laboratories, Inc. | Chemiluminescent phthalhydrazide-labeled hapten conjugates |
EP0082636B2 (en) * | 1981-12-11 | 2006-10-18 | The Welsh National School of Medicine | Luminescent labelling materials and procedures |
ATE42317T1 (en) * | 1983-07-29 | 1989-05-15 | Henning Berlin Gmbh | PRE-ACTIVATED PLASTIC SURFACES FOR IMMOBILIZATION OF ORGANIC CHEMICAL AND BIOLOGICAL MATERIALS, PROCESS FOR THE MANUFACTURE AND USE OF SAME. |
US4687747A (en) * | 1984-07-02 | 1987-08-18 | Mallinckrodt, Inc. | Phenanthridinium ester as a labelling compound in luminometric immunoassay |
JPS6261969A (en) * | 1985-09-06 | 1987-03-18 | アモコ・コーポレーション | Synthesis of acridinium ester |
DE3628573C2 (en) * | 1986-08-22 | 1994-10-13 | Hoechst Ag | Chemiluminescent acridine derivatives, processes for their preparation and their use in luminescence immunoassays |
EP0273115B1 (en) * | 1986-10-22 | 1994-09-07 | Abbott Laboratories | Chemiluminescent acridinium and phenanthridinium salts |
JPH0699401A (en) * | 1992-09-18 | 1994-04-12 | I N R Kenkyusho:Kk | Woodworking machine |
-
1988
- 1988-02-20 DE DE3844954A patent/DE3844954C2/en not_active Expired - Lifetime
-
1989
- 1989-02-14 AT AT89102487T patent/ATE195757T1/en not_active IP Right Cessation
- 1989-02-14 EP EP89102487A patent/EP0330050B1/en not_active Expired - Lifetime
- 1989-02-14 ES ES89102487T patent/ES2151474T3/en not_active Expired - Lifetime
- 1989-02-14 DE DE58909877T patent/DE58909877D1/en not_active Expired - Lifetime
- 1989-02-16 FI FI890754A patent/FI90537C/en not_active IP Right Cessation
- 1989-02-17 PT PT89759A patent/PT89759B/en not_active IP Right Cessation
- 1989-02-17 JP JP1036428A patent/JP2602315B2/en not_active Expired - Lifetime
- 1989-02-17 NO NO890689A patent/NO173237C/en not_active IP Right Cessation
- 1989-02-17 DK DK198900742A patent/DK175493B1/en not_active IP Right Cessation
- 1989-02-17 CA CA000591436A patent/CA1339390C/en not_active Expired - Lifetime
-
2000
- 2000-11-22 GR GR20000402577T patent/GR3034888T3/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO890689L (en) | 1989-08-21 |
JPH01261461A (en) | 1989-10-18 |
DK175493B1 (en) | 2004-11-08 |
PT89759A (en) | 1989-10-04 |
FI890754A0 (en) | 1989-02-16 |
EP0330050B1 (en) | 2000-08-23 |
FI890754A (en) | 1989-08-21 |
FI90537B (en) | 1993-11-15 |
EP0330050A3 (en) | 1991-11-06 |
NO173237B (en) | 1993-08-09 |
DK74289D0 (en) | 1989-02-17 |
DK74289A (en) | 1989-08-21 |
PT89759B (en) | 1994-03-31 |
FI90537C (en) | 1994-02-25 |
NO890689D0 (en) | 1989-02-17 |
DE3844954C2 (en) | 1998-07-16 |
ATE195757T1 (en) | 2000-09-15 |
GR3034888T3 (en) | 2001-02-28 |
CA1339390C (en) | 1997-08-26 |
EP0330050A2 (en) | 1989-08-30 |
ES2151474T3 (en) | 2001-01-01 |
DE58909877D1 (en) | 2000-09-28 |
JP2602315B2 (en) | 1997-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |