NO148136B - PREPARATION FOR FIGHTING HEADLUSES, BODYLUSES AND SIMILAR SKIN PARASITES FOR TROPICAL USE - Google Patents

PREPARATION FOR FIGHTING HEADLUSES, BODYLUSES AND SIMILAR SKIN PARASITES FOR TROPICAL USE

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Publication number
NO148136B
NO148136B NO782373A NO782373A NO148136B NO 148136 B NO148136 B NO 148136B NO 782373 A NO782373 A NO 782373A NO 782373 A NO782373 A NO 782373A NO 148136 B NO148136 B NO 148136B
Authority
NO
Norway
Prior art keywords
preparation
anionic surfactant
surfactant
ionic
similar skin
Prior art date
Application number
NO782373A
Other languages
Norwegian (no)
Other versions
NO782373L (en
NO148136C (en
Inventor
Stewart Thomas Leslie
Alan Rhodes
Original Assignee
Mundipharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma Ag filed Critical Mundipharma Ag
Publication of NO782373L publication Critical patent/NO782373L/en
Publication of NO148136B publication Critical patent/NO148136B/en
Publication of NO148136C publication Critical patent/NO148136C/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/463Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant

Description

Denne oppfinnelse angår et preparat for bekjempelse This invention relates to a preparation for fighting

av hodelus, kroppslus og lignende hudparasitter ved lokal applika- of head lice, body lice and similar skin parasites by local application

sjon på hud eller hår. tion on skin or hair.

De kjente kosmetiske geler er i alminnelighet hellbare The known cosmetic gels are generally pourable

geler som er dannet enten ved å tilsette et uorganisk salt til et alkylethersulfat eller ved at det i det kosmetiske preparat innlemmes cellulose, et alginat eller annet kjent, gummilignende fortykkningsmiddel. Disse kjente kosmetiske geler er vanlig- gels which are formed either by adding an inorganic salt to an alkyl ether sulphate or by incorporating cellulose, an alginate or other known rubber-like thickening agent into the cosmetic preparation. These known cosmetic gels are usually

vis badegeler som alt etter bruksområdet anvendes sammen med store mengder.vann, og som derfor ikke oppviser utpreget gelkonsistens innenfor et bredt område av omgivelsetemperaturer. show bath gels which, depending on the area of use, are used together with large quantities of water, and which therefore do not exhibit a distinct gel consistency within a wide range of ambient temperatures.

For bekjempelse av hodelus, Kroppslus og andre hudpara- For combating head lice, body lice and other skin para-

sitter har det vist seg ønskelig å behandle kroppen eller håret med et i vann uoppløselig aktivt stoff, f.eks. 1-nafthylmethyl- sitting, it has proved desirable to treat the body or hair with a water-insoluble active substance, e.g. 1-naphthylmethyl-

carbamat (carbaryl) , piperonyl- butoxyd og/eller et s-[ 1, 2-bis-(ethoxy-carbonyl)-ethyl]-0,0-dimethyldithiofosfat (malathion) eller corti-costeroid. For bekjempelse av hodelus og lignende er det i stor utstrekning blitt innlemmet aktive stoffer av denne type i kremer og salver for bruk i områder med temperert klima. I om- carbamate (carbaryl), piperonyl-butoxide and/or a s-[1, 2-bis-(ethoxy-carbonyl)-ethyl]-0,0-dimethyldithiophosphate (malathion) or corticosteroid. To combat head lice and the like, active substances of this type have largely been incorporated into creams and ointments for use in areas with a temperate climate. In about-

råder med tropisk klima vil imidlertid det anioniske overflate- prevails with a tropical climate, however, the anionic surface

aktive middel som i alminnelighet anvendes, såsom f.eks. natrium-laurylsulfat, oppløses i preparatet under dannelse av en væske i stedet for en krem. Ved senere avkjøling av preparatet krystall-iserer det overflateaktive middel ut av oppløsningen under dann- active agents that are generally used, such as e.g. sodium lauryl sulfate, dissolves in the preparation forming a liquid instead of a cream. Upon subsequent cooling of the preparation, the surface-active agent crystallizes out of the solution, forming

else av et produkt som inneholder korte nålelignende krystaller, other than a product containing short needle-like crystals,

som forstyrrer anvendelsen av det kosmetiske preparat. Fra US patentskrift nr. 3 352 753 er det kjent preparater for topisk anvendelse, som inneholder et corticoster6id som aktivt stoff, which interferes with the use of the cosmetic preparation. From US Patent No. 3 352 753 preparations for topical use are known, which contain a corticoster6id as active substance,

men som nå grunn av sitt høye innehold av polart oppløsningsmiddel f såsom vann eller ethylalkohol, taper sin gelkonsistens allerede ved temperaturer som ligger bare noe høyere enn vanlig romtemperatur slik at et preparat for topisk anvendelse som inneholder samme bærer som preparatet ifølge US patentskrift nr. 3 352 753, heller but which, due to its high content of polar solvent such as water or ethyl alcohol, loses its gel consistency already at temperatures that are only slightly higher than normal room temperature, so that a preparation for topical use containing the same carrier as the preparation according to US patent document no. 3 352 753, either

ikke vil være anvendelig i tropisk klima. will not be applicable in tropical climates.

Gelpreparater som er bestemt for annen administrering Gel preparations intended for other administration

enn topisk påføring, kan ikke anvendes topisk, da bestanddeler i disse irriterer huden og øynene og forårsaker konjunctivitis eller dermatitis. than topical application, cannot be used topically, as components in these irritate the skin and eyes and cause conjunctivitis or dermatitis.

Formålet med oppfinnelsen er å frembringe et preparat The purpose of the invention is to produce a preparation

for lokal applikasjon for bekjempelse av hodelus, kroppslus og lignende hudparasitter, hvilket preparat har en gelstruktur som bevares ved alle de temperaturer som kan være aktuelle ved normal bruk, og som kan påføres på huden hos mennesker eller dyr uten risiko for å irritere huden og øynene. for local application to combat head lice, body lice and similar skin parasites, which preparation has a gel structure that is preserved at all the temperatures that may be relevant in normal use, and which can be applied to the skin of humans or animals without the risk of irritating the skin and eyes .

I henhold tii oppfinnelsen tilveiebringes det således According to the invention it is thus provided

et preparat for bekjempelse av hodelus, kroppslus og lignende hudparasitter ved topisk anvendelse, hvilket preparat inneholder et anionaktivt, overflateaktivt stoff,ikke-ionogene overflateaktive stoffer, et polart oppløsningsmiddel og et aktivt stoff, såsom 1-nafthylmethylcarbamat, piperonylbutoxyd og/eller s-£i,2-bis-(ethoxycarbonyl)-ethyfj-0,O-dimethyl-dithiofosfat, og eventuelt farvestoffer og/eller luktstoffer. Det nye preparat ut-merker seg ved at det som anionaktivt, overflateaktivt stoff inneholder natriumlaurylethersulfat, som ikke-ionogene overflateaktive stoffer inneholder nonylfenoxypoly-(ethylenoxy)-ethanol, kokosnøttfettsyrediethanolamid og ethoxylert lanolin, og som polart oppløsningsmiddel inneholder vann, idet vektforholdet mellom anionaktivt, overflateaktivt stoff og ikke-ionogent overflateaktivt stoff er mellom 1:3 og 3:1, fortrinnsvis ca. 2:1, og at den totale mengde av anionaktivt, overflateaktivt stoff og ikke-ionogent overflateaktivt stoff utgjør mellom 20 og 60 vekt% av preparatet. a preparation for combating head lice, body lice and similar skin parasites by topical application, which preparation contains an anionic surface-active substance, non-ionic surfactants, a polar solvent and an active substance, such as 1-naphthylmethylcarbamate, piperonyl butoxyd and/or s-£ i,2-bis-(ethoxycarbonyl)-ethyl-O,O-dimethyl-dithiophosphate, and optionally dyes and/or odorants. The new preparation is distinguished by the fact that it contains sodium lauryl ether sulfate as an anionic surfactant, non-ionic surfactants contain nonylphenoxypoly-(ethyleneoxy)-ethanol, coconut fatty acid diethanolamide and ethoxylated lanolin, and as a polar solvent it contains water, since the weight ratio between anionic, surfactant and non-ionic surfactant is between 1:3 and 3:1, preferably approx. 2:1, and that the total amount of anionic surfactant and non-ionic surfactant constitutes between 20 and 60% by weight of the preparation.

Preparatet ifølge oppfinnelsen oppviser den fordel at overflateaktive midler og vannet som det inneholder ikke irriterer huden hos dyr eller mennesker og således ikke bevirker lidelser som dermatitis og konjunctivitis. The preparation according to the invention has the advantage that surfactants and the water it contains do not irritate the skin of animals or humans and thus do not cause disorders such as dermatitis and conjunctivitis.

Det antas at kombinasjonen av det anionaktiveoverflate-aktive middel med det ikke-ionogene overflateaktive middel i nær-vær av vann danner en co-micella-fase i oppløsningsmidlet som fører til geldannelse ved en økning i massevolumet av co-micella-fasen. Dette massevolum av de to overflateaktive midler bestemmer således geleringspunktet for preparatet, og det er av denne grunn at den foretrukne kombinerte prosent av det anion aktive overflateaktive middel og det ikke-ionooene overflateaktive middel i gelpreparatet ligger mellom 20 og 60 vekt%. It is believed that the combination of the anionic surfactant with the nonionic surfactant in the presence of water forms a co-micella phase in the solvent which leads to gel formation by an increase in the mass volume of the co-micella phase. This mass volume of the two surfactants thus determines the gelation point of the preparation, and it is for this reason that the preferred combined percentage of the anionic surfactant and the nonionic surfactant in the gel preparation is between 20 and 60% by weight.

Preparatet ifølge oppfinnelsen oppviser den fordel at de overflateaktive midler og vannet som det inneholder ikke irriterer huden hos dyr eller mennesker og således ikke bevirker lidelser som dermatitis og konjuntivitis. Preparatet ifølge oppfinnelsen kan med fordel fremstilles ved at det anionaktive, overflateaktive stoff i form av en pasta oppvarmes med det ikke-ion overflateaktive stoff, det aktive stoff oppløses i det overflateaktive stoff som det er oppløselig i, vannet tilsettes, og det hele omrøres inntil det er dannet en klar oppløsning, hvoretter det foretas avkjøling. The preparation according to the invention has the advantage that the surfactants and the water it contains do not irritate the skin of animals or humans and thus do not cause disorders such as dermatitis and conjunctivitis. The preparation according to the invention can advantageously be prepared by heating the anionic surface-active substance in the form of a paste with the non-ionic surfactant, the active substance is dissolved in the surfactant in which it is soluble, the water is added, and the whole is stirred until a clear solution is formed, after which cooling is carried out.

De følgende eksempler illustrerer oppfinnelsen. The following examples illustrate the invention.

Eksempel 1 Example 1

Natriuralaurylethersulfatet, kokos nøtt -diethanolamidet og Sodium lauryl ether sulfate, coconut diethanolamide and

det ethoxylerte lanolin blandes sammen ved en temperatur på 70 - 80 oC. Carbarylet oppløses i nonylfenoxypoly-(ethylenoxy)-ethanolen the ethoxylated lanolin is mixed together at a temperature of 70 - 80 oC. The carbaryl dissolves in the nonylphenoxypoly-(ethyleneoxy)-ethanol

ved oppvarmning til en temperatur på 40 - 50°C. Blandingen om-røres for å danne en klar oppløsning. Den erholdte oppløsning tilsettes til blandingen av natriumlaurylethersul fat, kokosnøtt-diethanolamidet og det ethoxylerte lanolin, og omrøres for å by heating to a temperature of 40 - 50°C. The mixture is stirred to form a clear solution. The resulting solution is added to the mixture of sodium lauryl ether sulfate, the coconut diethanolamide and the ethoxylated lanolin, and stirred to

danne en homogen oppløsning. form a homogeneous solution.

Farvestoffet oppløses fullstendig i den beregnede menger The dye dissolves completely in the calculated amount

vann, og den dannede oppløsning oppvarmes til en temperatur like under kokepunktet og tilsettes så langsomt til den ovenfor fremstilte homogene oppløsning. Den dannede blanding holdes ved en høy temperatur for å tillate luft å unnslippe. Blandingen av-kjøles så til 55 - 6o°C, og parfyme innrøres langsomt. Ved av-kjøling til værelsetemperatur dannes en gel som bibeholder sin geltilstand og foo i minst 2 år når den lagres ved værelsetemperatur eller 30°C. water, and the resulting solution is heated to a temperature just below the boiling point and then slowly added to the homogenous solution prepared above. The resulting mixture is kept at a high temperature to allow air to escape. The mixture is then cooled to 55 - 6o°C, and perfume is slowly stirred in. Upon cooling to room temperature, a gel is formed which retains its gel state and foo for at least 2 years when stored at room temperature or 30°C.

Eksempel 2 Example 2

Natriumlaurylethersulfatet, kokosnøtt-diethanolamidet og det ethoxylerte lanolin blandes sammen ved en temperatur på 70 - 80°C . Nonylfenoxypoly-(ethylenoxy)-ethanolen tilsettes så til blandingen som omrøres for å danne en homogen oppløsning. Farvestoffet oppløses fullstendig i den beregnede mengde vann, og den erholdte oppløsning oppvarmes til en temperatur like under kokepunktet og tilsettes så langsomt til den ovenfor fremstilte homogene oppløsning. The sodium lauryl ether sulfate, the coconut diethanolamide and the ethoxylated lanolin are mixed together at a temperature of 70 - 80°C. The nonylphenoxypoly-(ethyleneoxy)-ethanol is then added to the mixture which is stirred to form a homogeneous solution. The dye is completely dissolved in the calculated amount of water, and the resulting solution is heated to a temperature just below the boiling point and then slowly added to the homogenous solution prepared above.

Den dannede blanding holdes ved en høy temperatur for å tillate lu^t å unnslippe. Blandingen avkjøles så til 55 - 60°C og innstilles på pH 5,2 med fortynnet saltsyre. Malathionet og parfymen røres så langsomt inn i blandingen. Ved avkjøling til værelsetemperatur dannes en gel som bibeholder sin gelstruktur og fonn når den oppvarmes til en temperatur på minst 30°C. The resulting mixture is kept at a high temperature to allow air to escape. The mixture is then cooled to 55 - 60°C and adjusted to pH 5.2 with dilute hydrochloric acid. The malathion and the perfume are then slowly stirred into the mixture. When cooled to room temperature, a gel is formed which retains its gel structure and shape when heated to a temperature of at least 30°C.

Natriumlaurylethersulfatet, kokosnøtt-diethanolamidet og det ethoxylerte lanolin blandes sammen ved en temperatur på 70 - 80°C. Carbarylet, piperony1-butoxydet og isopropyl-myristatet oppløses i nonylfenoxypoly-(ethylenoxy)-ethanolen ved oppvarmning til en temperatur på ZfO - 50°C. Blandingen omrøres for å danne en klar oppløsning. The sodium lauryl ether sulfate, the coconut diethanolamide and the ethoxylated lanolin are mixed together at a temperature of 70 - 80°C. The carbaryl, the piperony-1-butoxide and the isopropyl myristate are dissolved in the nonylphenoxypoly-(ethyleneoxy)-ethanol by heating to a temperature of ZfO - 50°C. The mixture is stirred to form a clear solution.

Den erholdte oppløsning tilsettes til blandingen av natrium-laurylethersulf at , kokosnøtt-diethanolamidet og det ethoxylerte lanolin og omrøres for å danne en homogen oppløsning. Farvestoffet oppløses fullstendig i den beregnede mengde vann, og den erholdte oppløsning oppvarmes til en temperatur like under kokepunktet og tilsettes så langsomt til den ovenfor fremstilte homogene oppløsning. Den erholdte blanding holdes ved en høy temperatur for å tillate luft å unnslippe. Blandingen avkjøles så til 55 - 6o°C, og parfymen innrøres langsomt. The resulting solution is added to the mixture of sodium lauryl ether sulfate, the coconut diethanolamide and the ethoxylated lanolin and stirred to form a homogeneous solution. The dye is completely dissolved in the calculated amount of water, and the resulting solution is heated to a temperature just below the boiling point and then slowly added to the homogenous solution prepared above. The resulting mixture is kept at a high temperature to allow air to escape. The mixture is then cooled to 55 - 6o°C, and the perfume is slowly stirred in.

Ved avkjøling til værelsetemperatur dannes en gel som bibeholder sine gelegenskape 1: og form når den oppvarmes til en temperatur på minst 30°C. When cooled to room temperature, a gel is formed which retains its gel properties 1: and shape when heated to a temperature of at least 30°C.

Claims (3)

1. Preparat for bekjempelse av hodelus, kroppslus og lignende hudparasitter ved topisk anvendelse, hvilket prepara-rat inneholder et anionaktivt, overflateaktivt stoff, ikke-ionogene overflateaktive stoffer, et polart oppløsningsmiddel og et aktivt stoff, såsom 1-nafthylmethylcarbamat, piperonylbutoxyd og/eller s-[1,2-bis-(ethoxycarbonyl)-ethyl]-0,0-dimethyl-dithiofosfat, og eventuelt farvestoffer og/eller luktstoffer, karakterisert ved at det som anionaktivt overflateaktivt stoff inneholder natriumlaurylethersulfat, som ikke-ionogene overflateaktive stoffer inneholder nonyl-fenoxypoly-(ethylenoxy)-ethanol, kokosnøttfettsyrediethanol-amid og ethoxylert lanolin, og som polart oppløsningsmiddel inneholder vann, idet vektforholdet mellom anionaktivt, overflateaktivt stoff og ikke-ionogent overflateaktivt stoff er mellom 1:3 og 3:1, fortrinnsvis ca. 2:1, og at den totale mengde av anionaktivt overflateaktivt stoff og ikke-ionogent overflateaktivt stoff utgjør mellom 20 og 60 vekt% av preparatet.1. Preparation for combating head lice, body lice and similar skin parasites by topical application, which preparation contains an anionic surfactant, non-ionic surfactants, a polar solvent and an active substance, such as 1-naphthylmethylcarbamate, piperonyl butoxyd and/or s-[1,2-bis-(ethoxycarbonyl)-ethyl]-0,0-dimethyl-dithiophosphate, and optionally dyes and/or odorants, characterized in that it contains sodium lauryl ether sulfate as an anionic surfactant, non-ionic surfactants contain nonyl-phenoxypoly-(ethyleneoxy)-ethanol, coconut fatty acid diethanol-amide and ethoxylated lanolin, and as a polar solvent it contains water, the weight ratio between anionic surfactant and non-ionic surfactant is between 1:3 and 3:1, preferably approx. 2:1, and that the total amount of anionic surfactant and non-ionic surfactant constitutes between 20 and 60% by weight of the preparation. 2 . Preparat ifølge krav 1, karakterisert ved at det inneholder de følgende bestanddeler:2. Preparation according to claim 1, characterized in that it contains the following components: 3. Preparat ifølge krav 1, karakterisert ved at det inneholder de følgende bestanddeler:3. Preparation according to claim 1, characterized in that it contains the following components:
NO782373A 1977-07-08 1978-07-07 PREPARATION FOR COMBATING HEADLUSES, BODYLUSES AND SIMILAR SKIN PARASITES FOR TROPICAL USE NO148136C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2872277 1977-07-08

Publications (3)

Publication Number Publication Date
NO782373L NO782373L (en) 1979-01-09
NO148136B true NO148136B (en) 1983-05-09
NO148136C NO148136C (en) 1983-08-17

Family

ID=10280057

Family Applications (1)

Application Number Title Priority Date Filing Date
NO782373A NO148136C (en) 1977-07-08 1978-07-07 PREPARATION FOR COMBATING HEADLUSES, BODYLUSES AND SIMILAR SKIN PARASITES FOR TROPICAL USE

Country Status (13)

Country Link
AR (1) AR222305A1 (en)
BE (1) BE868239A (en)
CA (1) CA1099637A (en)
DK (1) DK306678A (en)
FI (1) FI70136C (en)
FR (1) FR2396546A1 (en)
GR (1) GR65307B (en)
IL (1) IL54972A (en)
MX (1) MX5148E (en)
NL (1) NL7805745A (en)
NO (1) NO148136C (en)
PT (1) PT68078B (en)
SE (1) SE7806690L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265384B1 (en) 1999-01-26 2001-07-24 Dale L. Pearlman Methods and kits for removing, treating, or preventing lice with driable pediculostatic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE932516C (en) * 1943-02-07 1955-09-01 Dehydag Gmbh Process for the production of jelly-like preparations
BE565499A (en) * 1957-03-07
FR1365793A (en) * 1963-08-08 1964-07-03 Shiseido Co Ltd Process for preparing jelly-like toilet articles and articles obtained by this process
DE2436028C3 (en) * 1974-07-26 1980-08-21 Eduard Gerlach Gmbh Chemische Fabrik, 4990 Luebbecke Use of diethylene glycol to destroy lice and their eggs / nits Eduard Gerlach GmbH Chemische Fabrik, 4990 Lübbecke
JPS5235204A (en) * 1975-09-16 1977-03-17 Kao Corp Clear high viscous liuid shampoo composition

Also Published As

Publication number Publication date
CA1099637A (en) 1981-04-21
NO782373L (en) 1979-01-09
NL7805745A (en) 1979-01-10
FI781815A (en) 1979-01-09
DK306678A (en) 1979-01-09
BE868239A (en) 1978-10-16
PT68078B (en) 1979-11-21
PT68078A (en) 1978-06-01
IL54972A (en) 1981-11-30
FI70136B (en) 1986-02-28
NO148136C (en) 1983-08-17
FI70136C (en) 1986-09-15
FR2396546A1 (en) 1979-02-02
GR65307B (en) 1980-08-01
AR222305A1 (en) 1981-05-15
FR2396546B1 (en) 1983-07-29
MX5148E (en) 1983-04-04
SE7806690L (en) 1979-01-09
IL54972A0 (en) 1978-08-31

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