NO147563C - ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 5- (2-FUROYL, 5- (2-TENOYL) -, 5- (3-FUROYL) - AND 5- (3-TENOYL) -1,2-DIHYDRO-3H-PYRROLO ( 1,2-A) pyrrole-1-carboxylic acid derivatives - Google Patents

ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 5- (2-FUROYL, 5- (2-TENOYL) -, 5- (3-FUROYL) - AND 5- (3-TENOYL) -1,2-DIHYDRO-3H-PYRROLO ( 1,2-A) pyrrole-1-carboxylic acid derivatives

Info

Publication number
NO147563C
NO147563C NO772493A NO772493A NO147563C NO 147563 C NO147563 C NO 147563C NO 772493 A NO772493 A NO 772493A NO 772493 A NO772493 A NO 772493A NO 147563 C NO147563 C NO 147563C
Authority
NO
Norway
Prior art keywords
tenoyl
furoyl
pyrrolo
pyrrole
dihydro
Prior art date
Application number
NO772493A
Other languages
Norwegian (no)
Other versions
NO147563B (en
NO772493L (en
Inventor
Joseph M Muchowski
Arthur F Kluge
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,283 external-priority patent/US4087539A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO772493L publication Critical patent/NO772493L/en
Publication of NO147563B publication Critical patent/NO147563B/en
Publication of NO147563C publication Critical patent/NO147563C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
NO772493A 1976-07-14 1977-07-13 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 5- (2-FUROYL, 5- (2-TENOYL) -, 5- (3-FUROYL) - AND 5- (3-TENOYL) -1,2-DIHYDRO-3H-PYRROLO ( 1,2-A) pyrrole-1-carboxylic acid derivatives NO147563C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70485776A 1976-07-14 1976-07-14
US05/771,283 US4087539A (en) 1976-07-14 1977-02-23 5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (3)

Publication Number Publication Date
NO772493L NO772493L (en) 1978-01-17
NO147563B NO147563B (en) 1983-01-24
NO147563C true NO147563C (en) 1983-05-18

Family

ID=27107392

Family Applications (1)

Application Number Title Priority Date Filing Date
NO772493A NO147563C (en) 1976-07-14 1977-07-13 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 5- (2-FUROYL, 5- (2-TENOYL) -, 5- (3-FUROYL) - AND 5- (3-TENOYL) -1,2-DIHYDRO-3H-PYRROLO ( 1,2-A) pyrrole-1-carboxylic acid derivatives

Country Status (26)

Country Link
JP (1) JPS539789A (en)
AR (1) AR218631A1 (en)
AU (1) AU513385B2 (en)
CA (1) CA1100140A (en)
CH (2) CH644861A5 (en)
CS (1) CS208724B2 (en)
DE (1) DE2731662A1 (en)
DK (1) DK152652C (en)
ES (2) ES460705A1 (en)
FI (1) FI63407C (en)
FR (1) FR2361396A1 (en)
GB (1) GB1554076A (en)
GR (1) GR61607B (en)
HK (1) HK17581A (en)
IE (1) IE45302B1 (en)
IL (1) IL52492A (en)
IT (1) IT1117314B (en)
MY (1) MY8100371A (en)
NL (1) NL7707652A (en)
NO (1) NO147563C (en)
NZ (1) NZ184611A (en)
PL (1) PL111408B1 (en)
PT (1) PT66779B (en)
SE (1) SE434644B (en)
SU (2) SU664566A3 (en)
YU (2) YU43157B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097579A (en) * 1977-03-31 1978-06-27 Syntex (U.S.A.) Inc. 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (en) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
HU198927B (en) * 1987-01-14 1989-12-28 Richter Gedeon Vegyeszet Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds

Also Published As

Publication number Publication date
NO147563B (en) 1983-01-24
CS208724B2 (en) 1981-09-15
FI63407C (en) 1983-06-10
PT66779A (en) 1977-08-01
YU43156B (en) 1989-04-30
NO772493L (en) 1978-01-17
SE7708142L (en) 1978-01-15
NZ184611A (en) 1979-03-28
CH651045A5 (en) 1985-08-30
DK152652B (en) 1988-04-05
ES470213A1 (en) 1979-09-16
ES460705A1 (en) 1979-10-01
NL7707652A (en) 1978-01-17
CH644861A5 (en) 1984-08-31
DK307677A (en) 1978-01-15
IL52492A (en) 1981-06-29
FR2361396A1 (en) 1978-03-10
YU47683A (en) 1984-04-30
PT66779B (en) 1978-12-18
PL199602A1 (en) 1979-01-29
DE2731662A1 (en) 1978-01-19
AU2697677A (en) 1979-01-18
HK17581A (en) 1981-05-08
AR218631A1 (en) 1980-06-30
GB1554076A (en) 1979-10-17
AU513385B2 (en) 1980-11-27
YU47583A (en) 1984-06-30
DE2731662C2 (en) 1989-11-09
FI63407B (en) 1983-02-28
IT1117314B (en) 1986-02-17
IE45302L (en) 1978-01-14
IE45302B1 (en) 1982-07-28
JPS6254110B2 (en) 1987-11-13
YU43157B (en) 1989-04-30
FI772154A (en) 1978-01-15
IL52492A0 (en) 1977-10-31
CA1100140A (en) 1981-04-28
MY8100371A (en) 1981-12-31
PL111408B1 (en) 1980-08-30
JPS539789A (en) 1978-01-28
SU664566A3 (en) 1979-05-25
GR61607B (en) 1978-12-02
SU793400A3 (en) 1980-12-30
DK152652C (en) 1988-09-12
FR2361396B1 (en) 1981-11-27
SE434644B (en) 1984-08-06

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