NL7901919A - Polymer compsn. contg. physiologically active cpd. - with controlled release mixt., prepd. by polymerising monomers with radiation at below room temp. (NL 11.9.79) - Google Patents
Polymer compsn. contg. physiologically active cpd. - with controlled release mixt., prepd. by polymerising monomers with radiation at below room temp. (NL 11.9.79)Info
- Publication number
- NL7901919A NL7901919A NL7901919A NL7901919A NL7901919A NL 7901919 A NL7901919 A NL 7901919A NL 7901919 A NL7901919 A NL 7901919A NL 7901919 A NL7901919 A NL 7901919A NL 7901919 A NL7901919 A NL 7901919A
- Authority
- NL
- Netherlands
- Prior art keywords
- mixt
- contg
- physiologically active
- below room
- room temp
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/44—Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Prodn. of a polymer compsn. (A) contg. a physiologically active substance (I) comprises combining >=1 polymerisable monomer (II) and (I) in a specific form (which may be a soln., suspension, microsphere or liq. film), then irradiating with ionising radiation or light at below room temp to polymerise (II). Pref. (I) and (II) are combined in presence or absence of a crystallisable substance, when an adsorbant (B) added and the mixt. irradiated at 0 degree C. (B) is esp. gelatine, agar, collagen, active carbon, silica gel, kaolin or an ion exchange resin. (I) is dispersed or simply mixed in a soln. made of a (co)polymer, soluble at pH 1-10, and (II), then polymerised. (I) is released at a controllable rate determined eg. by the nature of (II) and presence or amt. of (B). Use of low temp. polymerisation avoids decompsn. of (I) and need for a catalyst. (I) can be any pharmaceutical for use in human or veterinary medicine, an agricultural chemical, insecticide, growth regulator (for plants or micro-organisms) or cpd. useful in the food and pharmaceutical industries, eg. an enzyme stabiliser or auxiliary.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2710978A JPS54119585A (en) | 1978-03-09 | 1978-03-09 | Production of polymer composition containing physiologically active substance |
| JP5123978A JPS588402B2 (en) | 1978-04-28 | 1978-04-28 | Method for producing polymer composition |
| JP10530678A JPS5533412A (en) | 1978-08-29 | 1978-08-29 | Preparation of slow-releasing formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7901919A true NL7901919A (en) | 1979-09-11 |
Family
ID=27285666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7901919A NL7901919A (en) | 1978-03-09 | 1979-03-09 | Polymer compsn. contg. physiologically active cpd. - with controlled release mixt., prepd. by polymerising monomers with radiation at below room temp. (NL 11.9.79) |
Country Status (1)
| Country | Link |
|---|---|
| NL (1) | NL7901919A (en) |
-
1979
- 1979-03-09 NL NL7901919A patent/NL7901919A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1A | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BV | The patent application has lapsed |