NL7800268A - Medicament compsns. with good resorption properties - comprising solns. or suspensions in partial glyceride(s) - Google Patents
Medicament compsns. with good resorption properties - comprising solns. or suspensions in partial glyceride(s)Info
- Publication number
- NL7800268A NL7800268A NL7800268A NL7800268A NL7800268A NL 7800268 A NL7800268 A NL 7800268A NL 7800268 A NL7800268 A NL 7800268A NL 7800268 A NL7800268 A NL 7800268A NL 7800268 A NL7800268 A NL 7800268A
- Authority
- NL
- Netherlands
- Prior art keywords
- compsns
- solns
- suspensions
- medicament
- partial glyceride
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Abstract
Pharmaceutical compsns. with high enteral resorbability comprise solns. or microcrystalline suspensions of medicaments having low natural resorbability in partial glycerides of long-chain fatty acids. The partial glycerides can be mono- and/or diglucerides of satd. and/or unsatd. 12-18C (pref. 14-18C) fatty acids, esp. palmitic, stearic and/or oleic acid. The compsns. have higher activity (as measured by LD50 values) and give higher blood levels and renal excretion rates than compsns. based on conventional vehicles (e.g. H2O or tylose) when administered orally or rectally.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7800268A NL7800268A (en) | 1978-01-09 | 1978-01-09 | Medicament compsns. with good resorption properties - comprising solns. or suspensions in partial glyceride(s) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7800268A NL7800268A (en) | 1978-01-09 | 1978-01-09 | Medicament compsns. with good resorption properties - comprising solns. or suspensions in partial glyceride(s) |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7800268A true NL7800268A (en) | 1979-07-11 |
Family
ID=19830114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7800268A NL7800268A (en) | 1978-01-09 | 1978-01-09 | Medicament compsns. with good resorption properties - comprising solns. or suspensions in partial glyceride(s) |
Country Status (1)
Country | Link |
---|---|
NL (1) | NL7800268A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5525355A (en) * | 1993-09-14 | 1996-06-11 | Euro-Celtique, S.A. | Laxative compositions |
-
1978
- 1978-01-09 NL NL7800268A patent/NL7800268A/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5525355A (en) * | 1993-09-14 | 1996-06-11 | Euro-Celtique, S.A. | Laxative compositions |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BV | The patent application has lapsed |