NL7708930A - Synergistic anthelmintic esp. fasciolicide combinations - contg. a bis-acylamino-phenoxy-alkane and a benzimidazole - Google Patents

Synergistic anthelmintic esp. fasciolicide combinations - contg. a bis-acylamino-phenoxy-alkane and a benzimidazole

Info

Publication number
NL7708930A
NL7708930A NL7708930A NL7708930A NL7708930A NL 7708930 A NL7708930 A NL 7708930A NL 7708930 A NL7708930 A NL 7708930A NL 7708930 A NL7708930 A NL 7708930A NL 7708930 A NL7708930 A NL 7708930A
Authority
NL
Netherlands
Prior art keywords
alkyl
fasciolicide
contg
esp
acylamino
Prior art date
Application number
NL7708930A
Other languages
Dutch (nl)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB33827/76A external-priority patent/GB1596621A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NL7708930A publication Critical patent/NL7708930A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New combinations contain (a) a cpd. of formula (I) or a salt together with (b) a potentiating benzimidaozle, excluding the combination of diamphenethid e with oxfendazole or one of its saltS. In formula (I), G an dG1 are H, saturated 1-7C hydrocarbyl (opt. substd. by OH, NH2, mono- or di(1-4C alkyl)amino or 1-4C acyl) or unsaturated 2-4C hydrocarbyl; G2 and G3 are H or 1-4C alkyl; and G4 is -CH2-,-(CH2)2-, -CH2-O-CH2- or the group -C2(G5)H3-O-C2(G6)H3- in whichG5 and G6 are H or 1-3C alkyl. The new combinations are useful in the prophylaxis and treatment of helminth infections. They are partic. active gainst liver fluke. The effective dosage of (I) against fascioliasis is decreased by certain benzimidazole derivs. Specific cpds. (I) include diamphenethide, and specific potentiating benzimidazoles include fenbendazole.
NL7708930A 1976-08-13 1977-08-12 Synergistic anthelmintic esp. fasciolicide combinations - contg. a bis-acylamino-phenoxy-alkane and a benzimidazole NL7708930A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB33827/76A GB1596621A (en) 1976-08-13 1976-08-13 Anthelmintic ether combinations
GB4072276 1976-09-30
GB4502776 1976-10-29

Publications (1)

Publication Number Publication Date
NL7708930A true NL7708930A (en) 1978-02-15

Family

ID=27259166

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7708930A NL7708930A (en) 1976-08-13 1977-08-12 Synergistic anthelmintic esp. fasciolicide combinations - contg. a bis-acylamino-phenoxy-alkane and a benzimidazole

Country Status (1)

Country Link
NL (1) NL7708930A (en)

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Legal Events

Date Code Title Description
BV The patent application has lapsed