NL7609853A - Neoplasms immunological diagnosis - using cancer antigen NEA or its antibodies (NL070377) - Google Patents
Neoplasms immunological diagnosis - using cancer antigen NEA or its antibodies (NL070377)Info
- Publication number
- NL7609853A NL7609853A NL7609853A NL7609853A NL7609853A NL 7609853 A NL7609853 A NL 7609853A NL 7609853 A NL7609853 A NL 7609853A NL 7609853 A NL7609853 A NL 7609853A NL 7609853 A NL7609853 A NL 7609853A
- Authority
- NL
- Netherlands
- Prior art keywords
- nea
- antibodies
- neoplasms
- tumours
- neoplasm
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 8
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 230000001900 immune effect Effects 0.000 title 1
- 208000035269 cancer or benign tumor Diseases 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000769223 Thenea Species 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 239000003957 anion exchange resin Substances 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000035931 haemagglutination Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57476—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncofetal proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
Abstract
New neoplasm diagnostic agents contain NEA and/or NEA antibodies. NEA i a new type of neoplasm antigen found in embryonic and neoplastic tissues. NEA is detected by radioimmno methods utilising NEA or NEA antibodies labelled with a radiactive isotope or by haemagglutination using NEA or NEA antibodies. In the prodn. of NEA antibodies, animals are immunised with NEA or an NEA/antibody complex and the antiserum is recovered. The NEA and NEA antibodies are purified by affinity chromatography. The NEA-contg. mixt. is contacted with a basic anion-exchange resin. Unlike other tumour antigens, NEA is not specific to tumours of particular tissues, but can occur in e.g., breast, gastric or live tumours, so that tests based on NEA can be used for detecting a variety of neoplasms.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10588275A JPS5949544B2 (en) | 1975-09-03 | 1975-09-03 | Method for producing NEA antibody for neoplasm diagnosis |
| JP10588375A JPS6049866B2 (en) | 1975-09-03 | 1975-09-03 | Purification method for NEA and NEA antibodies |
| JP50106483A JPS6057021B2 (en) | 1975-09-04 | 1975-09-04 | Manufacturing method for neoplasm diagnostic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7609853A true NL7609853A (en) | 1977-03-07 |
Family
ID=27310597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7609853A NL7609853A (en) | 1975-09-03 | 1976-09-03 | Neoplasms immunological diagnosis - using cancer antigen NEA or its antibodies (NL070377) |
Country Status (1)
| Country | Link |
|---|---|
| NL (1) | NL7609853A (en) |
-
1976
- 1976-09-03 NL NL7609853A patent/NL7609853A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| BV | The patent application has lapsed |