NL7505633A - Werkwijze voor het bereiden van moleculaire verbindingen van indoolderivaten. - Google Patents

Werkwijze voor het bereiden van moleculaire verbindingen van indoolderivaten.

Info

Publication number
NL7505633A
NL7505633A NL7505633A NL7505633A NL7505633A NL 7505633 A NL7505633 A NL 7505633A NL 7505633 A NL7505633 A NL 7505633A NL 7505633 A NL7505633 A NL 7505633A NL 7505633 A NL7505633 A NL 7505633A
Authority
NL
Netherlands
Prior art keywords
molecular compounds
indole derivatives
preparing molecular
preparing
indole
Prior art date
Application number
NL7505633A
Other languages
English (en)
Other versions
NL166467B (nl
NL166467C (nl
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7992367A external-priority patent/JPS526983B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of NL7505633A publication Critical patent/NL7505633A/nl
Publication of NL166467B publication Critical patent/NL166467B/nl
Application granted granted Critical
Publication of NL166467C publication Critical patent/NL166467C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Indole Compounds (AREA)
NL7505633.A 1967-04-11 1975-05-14 Werkwijze voor het bereiden van een therapeutisch werk- zaam 1- (p-chloorbenzoyl)-2-methyl-5-methoxy-3-indolyl- acetaat, alsmede van een vast injectiepreparaat dat een 1-(p-chloorbenzoyl)-2-methyl-5-methoxy-3-indolylace- taat bevat. NL166467C (nl)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2333767 1967-04-11
JP2882567 1967-05-06
JP2931167 1967-05-08
JP3303867 1967-05-23
JP3388567 1967-05-27
JP3442767 1967-05-29
JP7207967 1967-11-08
JP7992367A JPS526983B1 (nl) 1967-12-12 1967-12-12
JP8032367 1967-12-14

Publications (3)

Publication Number Publication Date
NL7505633A true NL7505633A (nl) 1975-08-29
NL166467B NL166467B (nl) 1981-03-16
NL166467C NL166467C (nl) 1981-08-17

Family

ID=27576755

Family Applications (3)

Application Number Title Priority Date Filing Date
NL6804994A NL6804994A (nl) 1967-04-11 1968-04-09
NL7213495A NL7213495A (nl) 1967-04-11 1972-10-05
NL7505633.A NL166467C (nl) 1967-04-11 1975-05-14 Werkwijze voor het bereiden van een therapeutisch werk- zaam 1- (p-chloorbenzoyl)-2-methyl-5-methoxy-3-indolyl- acetaat, alsmede van een vast injectiepreparaat dat een 1-(p-chloorbenzoyl)-2-methyl-5-methoxy-3-indolylace- taat bevat.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NL6804994A NL6804994A (nl) 1967-04-11 1968-04-09
NL7213495A NL7213495A (nl) 1967-04-11 1972-10-05

Country Status (4)

Country Link
US (1) US3669987A (nl)
BR (1) BR6898229D0 (nl)
FR (1) FR7667M (nl)
NL (3) NL6804994A (nl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU162374B (nl) * 1969-04-03 1973-02-28
BE756975A (fr) * 1970-06-09 1971-04-02 Merck & Co Inc Suppositoires
US3730954A (en) * 1971-11-22 1973-05-01 Tenneco Chem N-(substituted indazolyl-n{11 -methyl)hexamethylenetetraammonium halides
GB1531546A (en) * 1976-05-19 1978-11-08 Pierrel Spa Anti-inflammatory indole derivative
IT1210859B (it) * 1982-03-01 1989-09-29 Ausonia Farma Srl Composto chemioterapico, procedimento per la sua preparazione e relative composizioni farmaceutiche.
US5466824A (en) * 1989-05-22 1995-11-14 Biochemical Veterinary Research Pty. Ltd. Divalent metal complexes of indomethacin, compositions and medical methods of use thereof
CA2058754C (en) * 1989-05-22 2002-02-19 Hubertus L. Regtop Divalent metal salts of indomethacin
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
ES2452343T3 (es) * 2006-09-29 2014-04-01 Glaxosmithkline Llc Compuestos de indol sustituidos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3242185A (en) * 1963-10-07 1966-03-22 Merck & Co Inc Lower aliphatic acids, salts and derivatives thereof
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
NL125443C (nl) * 1963-06-06

Also Published As

Publication number Publication date
FR7667M (nl) 1970-02-09
NL7213495A (nl) 1973-02-26
US3669987A (en) 1972-06-13
NL166467B (nl) 1981-03-16
BR6898229D0 (pt) 1973-04-17
NL6804994A (nl) 1968-10-14
NL166467C (nl) 1981-08-17

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Legal Events

Date Code Title Description
V4 Discontinued because of reaching the maximum lifetime of a patent