NL7310041A - - Google Patents

Info

Publication number
NL7310041A
NL7310041A NL7310041A NL7310041A NL7310041A NL 7310041 A NL7310041 A NL 7310041A NL 7310041 A NL7310041 A NL 7310041A NL 7310041 A NL7310041 A NL 7310041A NL 7310041 A NL7310041 A NL 7310041A
Authority
NL
Netherlands
Application number
NL7310041A
Other versions
NL149168B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7310041A publication Critical patent/NL7310041A/xx
Publication of NL149168B publication Critical patent/NL149168B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL737310041A 1972-07-20 1973-07-19 Werkwijze voor het bereiden van een geneesmiddel met bloeddruk-verlagende werking, waarin als actieve verbinding een veretherd 1-(3-hydroxypropyl)-4-fenyl- of -4-(fenylalkyl)-piperazine-derivaat is opgenomen, het volgens deze werkwijze verkregen geneesmiddel en werkwijze voor het bereiden van de actieve verbinding. NL149168B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2235597A DE2235597A1 (de) 1972-07-20 1972-07-20 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
NL7310041A true NL7310041A (US20020167097A1-20021114-C00005.png) 1974-01-22
NL149168B NL149168B (nl) 1976-04-15

Family

ID=5851155

Family Applications (1)

Application Number Title Priority Date Filing Date
NL737310041A NL149168B (nl) 1972-07-20 1973-07-19 Werkwijze voor het bereiden van een geneesmiddel met bloeddruk-verlagende werking, waarin als actieve verbinding een veretherd 1-(3-hydroxypropyl)-4-fenyl- of -4-(fenylalkyl)-piperazine-derivaat is opgenomen, het volgens deze werkwijze verkregen geneesmiddel en werkwijze voor het bereiden van de actieve verbinding.

Country Status (14)

Country Link
US (1) US3947446A (US20020167097A1-20021114-C00005.png)
JP (1) JPS5331158B2 (US20020167097A1-20021114-C00005.png)
AR (1) AR196775A1 (US20020167097A1-20021114-C00005.png)
AT (1) AT330188B (US20020167097A1-20021114-C00005.png)
CA (1) CA1003836A (US20020167097A1-20021114-C00005.png)
CH (2) CH583721A5 (US20020167097A1-20021114-C00005.png)
DD (1) DD106842A5 (US20020167097A1-20021114-C00005.png)
DE (1) DE2235597A1 (US20020167097A1-20021114-C00005.png)
ES (1) ES416929A1 (US20020167097A1-20021114-C00005.png)
FR (1) FR2193598B1 (US20020167097A1-20021114-C00005.png)
GB (1) GB1376588A (US20020167097A1-20021114-C00005.png)
HU (1) HU165887B (US20020167097A1-20021114-C00005.png)
NL (1) NL149168B (US20020167097A1-20021114-C00005.png)
ZA (1) ZA734811B (US20020167097A1-20021114-C00005.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL175059C (nl) * 1974-02-23 Boehringer Mannheim Gmbh Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
DE2658762A1 (de) * 1976-12-24 1978-06-29 Hoechst Ag Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB1583372A (en) * 1977-04-04 1981-01-28 Degussa 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives
US4101723A (en) * 1977-04-05 1978-07-18 E. R. Squibb & Sons, Inc. Substituted piperazinopropanols
US4259327A (en) * 1979-04-02 1981-03-31 Merck & Co., Inc. Substituted aminoalkoxypyridines, compositions and use thereof
US4255426A (en) * 1979-07-09 1981-03-10 Pfizer Inc. 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
DE3918542A1 (de) * 1989-06-07 1990-12-13 Boehringer Mannheim Gmbh Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IT1255178B (it) * 1992-06-26 1995-10-20 Pierrel Spa N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica
CA2332275A1 (en) * 1998-05-14 1999-11-18 Zoltan Tamas Nagy Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
EP1425261A2 (de) * 2001-08-31 2004-06-09 Bayer Chemicals AG Verfahren zur herstellung von 4-amino-1-naphtholethern

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1317034A (en) * 1970-11-06 1973-05-16 Pfizer Ltd 1-2-hydroxy-3-phenoxy- or -phenylthiopropyl-piperazine derivatives

Also Published As

Publication number Publication date
US3947446A (en) 1976-03-30
FR2193598A1 (US20020167097A1-20021114-C00005.png) 1974-02-22
DD106842A5 (US20020167097A1-20021114-C00005.png) 1974-07-05
JPS4943990A (US20020167097A1-20021114-C00005.png) 1974-04-25
FR2193598B1 (US20020167097A1-20021114-C00005.png) 1977-07-15
HU165887B (US20020167097A1-20021114-C00005.png) 1974-12-28
AR196775A1 (es) 1974-02-19
ES416929A1 (es) 1976-03-01
CH583722A5 (US20020167097A1-20021114-C00005.png) 1977-01-14
AT330188B (de) 1976-06-25
ZA734811B (en) 1974-07-31
NL149168B (nl) 1976-04-15
CA1003836A (en) 1977-01-18
DE2235597A1 (de) 1974-01-31
GB1376588A (en) 1974-12-04
CH583721A5 (US20020167097A1-20021114-C00005.png) 1977-01-14
JPS5331158B2 (US20020167097A1-20021114-C00005.png) 1978-08-31
ATA636673A (de) 1975-09-15

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