NL7104305A - Substd androst-4-ene-3-one lactone - diuretic etc. - Google Patents

Substd androst-4-ene-3-one lactone - diuretic etc.

Info

Publication number
NL7104305A
NL7104305A NL7104305A NL7104305A NL7104305A NL 7104305 A NL7104305 A NL 7104305A NL 7104305 A NL7104305 A NL 7104305A NL 7104305 A NL7104305 A NL 7104305A NL 7104305 A NL7104305 A NL 7104305A
Authority
NL
Netherlands
Prior art keywords
androst
lactone
ene
substd
diuretic
Prior art date
Application number
NL7104305A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7104305A publication Critical patent/NL7104305A/en

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  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

7 alpha-Acetylthio-17 alpha-(2-carboxyethyl)-17 beta-hydroxy-androst-4-ene-3-one lactone (I) is prepared by heating the 7-unsubstd. 4,6-diene-3-one with thioacetic acid in a polar solvent. The product is 95-98% 7 alpha-isomer. I is a diuretic and aldosterone antagonist.
NL7104305A 1970-03-31 1971-03-31 Substd androst-4-ene-3-one lactone - diuretic etc. NL7104305A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI000388 1970-03-31

Publications (1)

Publication Number Publication Date
NL7104305A true NL7104305A (en) 1971-10-04

Family

ID=11000835

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7104305A NL7104305A (en) 1970-03-31 1971-03-31 Substd androst-4-ene-3-one lactone - diuretic etc.

Country Status (2)

Country Link
JP (1) JPS5417733B1 (en)
NL (1) NL7104305A (en)

Also Published As

Publication number Publication date
JPS5417733B1 (en) 1979-07-02

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