NL6605692A - - Google Patents

Info

Publication number
NL6605692A
NL6605692A NL6605692A NL6605692A NL6605692A NL 6605692 A NL6605692 A NL 6605692A NL 6605692 A NL6605692 A NL 6605692A NL 6605692 A NL6605692 A NL 6605692A NL 6605692 A NL6605692 A NL 6605692A
Authority
NL
Netherlands
Application number
NL6605692A
Other versions
NL143550B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6605692A publication Critical patent/NL6605692A/xx
Publication of NL143550B publication Critical patent/NL143550B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL666605692A 1965-04-30 1966-04-28 Werkwijze voor de bereiding van een geneesmiddel met blokkeringseffect ten opzichte van hartstimulantia, dat als actieve verbinding een 1-(gesubstitueerd fenoxy)-2-hydroxy-3-isopropylaminopropaan en/of een zout daarvan bevat, en werkwijze voor de bereiding van de actieve verbinding. NL143550B (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE571165 1965-04-30
US55822666A 1966-06-17 1966-06-17

Publications (2)

Publication Number Publication Date
NL6605692A true NL6605692A (US06566495-20030520-M00011.png) 1966-10-31
NL143550B NL143550B (nl) 1974-10-15

Family

ID=26654650

Family Applications (1)

Application Number Title Priority Date Filing Date
NL666605692A NL143550B (nl) 1965-04-30 1966-04-28 Werkwijze voor de bereiding van een geneesmiddel met blokkeringseffect ten opzichte van hartstimulantia, dat als actieve verbinding een 1-(gesubstitueerd fenoxy)-2-hydroxy-3-isopropylaminopropaan en/of een zout daarvan bevat, en werkwijze voor de bereiding van de actieve verbinding.

Country Status (11)

Country Link
US (3) US3466325A (US06566495-20030520-M00011.png)
JP (3) JPS50653B1 (US06566495-20030520-M00011.png)
BE (1) BE678208A (US06566495-20030520-M00011.png)
BR (1) BR6678981D0 (US06566495-20030520-M00011.png)
CH (1) CH484053A (US06566495-20030520-M00011.png)
DE (1) DE1294955B (US06566495-20030520-M00011.png)
FI (2) FI42955B (US06566495-20030520-M00011.png)
FR (1) FR5745M (US06566495-20030520-M00011.png)
GB (2) GB1140860A (US06566495-20030520-M00011.png)
NL (1) NL143550B (US06566495-20030520-M00011.png)
NO (1) NO115797B (US06566495-20030520-M00011.png)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004017964A1 (en) 2002-08-19 2004-03-04 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
WO2007024945A1 (en) 2005-08-25 2007-03-01 Novartis Ag Condensed imidazolo derivatives for the inhibition of aldosterone synthase and aromatase
WO2007062314A2 (en) 2005-11-23 2007-05-31 Bristol-Myers Squibb Company Heterocyclic cetp inhibitors
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
WO2011069038A2 (en) 2009-12-03 2011-06-09 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2392567A1 (en) 2005-10-21 2011-12-07 Bristol-Myers Squibb Company Benzothiazine derivatives and their use as lxr modulators
WO2013138352A1 (en) 2012-03-15 2013-09-19 Synergy Pharmaceuticals Inc. Formulations of guanylate cyclase c agonists and methods of use
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014170786A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
EP2810951A2 (en) 2008-06-04 2014-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2014197720A2 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same
EP2998314A1 (en) 2007-06-04 2016-03-23 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3241839A1 (en) 2008-07-16 2017-11-08 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3969512A (en) * 1935-11-15 1976-07-13 Boehringer Ingelheim Gmbh N,N'bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamines and salts thereof
SE354851B (US06566495-20030520-M00011.png) * 1970-02-18 1973-03-26 Haessle Ab
US3959486A (en) * 1970-05-27 1976-05-25 Imperial Chemical Industries Limited Method for producing β-adrenergic blockage with alkanolamine derivatives
US4059622A (en) * 1970-05-27 1977-11-22 Imperial Chemical Industries Limited Alkanolamine derivatives
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
US4018825A (en) * 1972-07-27 1977-04-19 Warner-Lambert Company 5-Hydroxy-α-(substituted aminomethyl)-m-xylene-α,α'-diols
US4067904A (en) * 1975-12-19 1978-01-10 Mead Johnson & Company Alkylsulfonylphenoxypropanolamine derivatives
US4119729A (en) * 1975-12-19 1978-10-10 Mead Johnson & Company Alkylsulfonylphenoxypropanolamine therapeutic process
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2963311D1 (en) * 1978-12-29 1982-08-26 Ciba Geigy Ag Propenyl-substituted phenolglycidyl ethers, process for their preparation and their use
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5254595A (en) * 1988-12-23 1993-10-19 Elf Sanofi Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them
JP2780559B2 (ja) * 1991-01-25 1998-07-30 信越化学工業株式会社 アリル基又はプロペニル基を持つナフタレン誘導体
CA2134038C (en) * 1994-06-16 1997-06-03 David Taiwai Wong Potentiation of drug response
EP0714663A3 (en) 1994-11-28 1997-01-15 Lilly Co Eli Potentiation of drug responses by serotonin 1A receptor antagonists
DK0759299T3 (da) * 1995-08-16 2000-08-07 Lilly Co Eli Potensering af serotoninrespons
US7034059B2 (en) * 2001-07-02 2006-04-25 Sepracor Inc. Methods of using norfluoxetine
US20030087963A1 (en) 2001-09-13 2003-05-08 Senanayake Chris H. Methods of preparing and using 2-hydroxy derivatives of sibutramine and its metabolites
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
EP2050441A1 (en) 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP2959904A1 (en) 2014-06-27 2015-12-30 Institut De Recerca Contra La Leucemia Josep Carreras Methods for treating, diagnosing and prognosing a haematological malignancy
FR3030514A1 (fr) * 2014-12-18 2016-06-24 Centre De Coop Int En Rech Agronomique Pour Le Dev (Cirad) Dimeres polyaromatiques

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2967201A (en) * 1958-06-02 1961-01-03 Lilly Co Eli Alkylaminoalkyl ethers of phenols
NL300886A (US06566495-20030520-M00011.png) * 1962-11-23
NL301580A (US06566495-20030520-M00011.png) * 1962-12-11
GB1069345A (en) * 1963-07-19 1967-05-17 Ici Ltd New alkanolamine derivatives
NL131194C (US06566495-20030520-M00011.png) * 1963-07-19
DE1493454C3 (de) * 1963-08-26 1980-04-30 C.H. Boehringer Sohn, 6507 Ingelheim 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel
CH455834A (de) * 1964-10-14 1968-05-15 Ciba Geigy Verfahren zur Herstellung des neuen 1-Isopropylamino-2-hydroxy-3-(2'-isopropoxy-phenoxy)-propans oder seinen Salzen

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004017964A1 (en) 2002-08-19 2004-03-04 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
WO2007024945A1 (en) 2005-08-25 2007-03-01 Novartis Ag Condensed imidazolo derivatives for the inhibition of aldosterone synthase and aromatase
EP2256118A1 (en) 2005-08-25 2010-12-01 Novartis AG Condensed imidazolo derivatives for the inhibition of aromatase
EP2270011A1 (en) 2005-08-25 2011-01-05 Novartis AG Condensed imidazolo derivatives for the inhibition of aromatase
EP2392567A1 (en) 2005-10-21 2011-12-07 Bristol-Myers Squibb Company Benzothiazine derivatives and their use as lxr modulators
WO2007062314A2 (en) 2005-11-23 2007-05-31 Bristol-Myers Squibb Company Heterocyclic cetp inhibitors
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
EP2998314A1 (en) 2007-06-04 2016-03-23 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2810951A2 (en) 2008-06-04 2014-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839A1 (en) 2008-07-16 2017-11-08 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
EP2923706A1 (en) 2009-12-03 2015-09-30 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia
WO2011069038A2 (en) 2009-12-03 2011-06-09 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2013138352A1 (en) 2012-03-15 2013-09-19 Synergy Pharmaceuticals Inc. Formulations of guanylate cyclase c agonists and methods of use
EP3708179A1 (en) 2012-03-15 2020-09-16 Bausch Health Ireland Limited Formulations of guanylate cyclase c agonists and methods of use
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014170786A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2014197720A2 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds

Also Published As

Publication number Publication date
US3466325A (en) 1969-09-09
DE1294955B (de) 1969-05-14
JPS4930819B1 (US06566495-20030520-M00011.png) 1974-08-16
FR5745M (US06566495-20030520-M00011.png) 1968-01-29
BR6678981D0 (pt) 1973-09-18
US3631108A (en) 1971-12-28
CH484053A (de) 1970-01-15
GB1140860A (en) 1969-01-22
NL143550B (nl) 1974-10-15
BE678208A (US06566495-20030520-M00011.png) 1966-09-01
FI42955B (US06566495-20030520-M00011.png) 1970-09-02
US3466376A (en) 1969-09-09
GB1140508A (en) 1969-01-22
NO115797B (US06566495-20030520-M00011.png) 1968-12-09
JPS50653B1 (US06566495-20030520-M00011.png) 1975-01-10
FI44392B (US06566495-20030520-M00011.png) 1971-08-02
JPS4929182B1 (US06566495-20030520-M00011.png) 1974-08-01

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Legal Events

Date Code Title Description
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: HASSLE

V4 Discontinued because of reaching the maximum lifetime of a patent