NL2035751A

NL2035751A - Multifunctional plasma surgical system

Info

Publication number: NL2035751A
Application number: NL2035751A
Authority: NL
Inventors: Zhang Yazhuo; Li Chuzhong; Yan Xu; Liu Yixiao; Zhang Yuqi; Fang Qiuyue; Xu Xiaojin; Liu Yulou
Original assignee: Chengdu Jingcheng Tech Co Ltd; Beijing Neurosurgical Inst
Priority date: 2022-09-07
Filing date: 2023-09-06
Publication date: 2024-03-14
Also published as: CN218870455U

Abstract

MULTIFUNCTIONAL PLASMA SURGICAL SYSTEM 5 A multifunctional plasma surgical system, belonging to the ﬁeld of medical instruments. An AC mains interface is connected with a DC power module, a plasma power module and a plasma jet power module are connected in parallel to the DC power module and a gating switch is arranged, the plasma power module, a plasma output interface and a plasma cutter head are connected in sequence, the plasma jet power module, a plasma jet output 10 interface and a jet cutter head are connected in sequence, and a main control module is connected with a liquid ﬂow control module, an airflow control module, the plasma power module and the plasma jet power module. Fig. l

Description

MULTIFUNCTIONAL PLASMA SURGICAL SYSTEM

Cross-reference of related applications

[0001] This application claims priority to Chinese patent application No. 202222377325 4, filed with the China National Intellectual Property Administration on September 07, 2022 and entitled " MULTIFUNCTIONAL PLASMA SURGICAL SYSTEM ", the disclosure of which is hereby incorporated by reference in its entirety.

Technical Field

[0002] The present application relates to the field of medical instruments, in particular to a multifunctional plasma surgical system.

Background Art

[0003] A plasma is composed of ions, electrons and non-ionized neutral ions, presenting a neutral substance state as a whole. The plasma can be divided into a high temperature plasma and a low temperature plasma according to different plasma temperatures.

[0004] The low temperature plasma can excite Na", Cl, H* and OH" in saline water by a current of 100kHz to form plasma. At a lower temperature, not only efficient tissue cutting and ablation effects can be achieved, but also coagulation and hemostasis effects can be achieved. Since the plasma has the same cutting effect as a “knife”, the plasma is also called a “plasma knife” clinically. In recent years, the low temperature plasma technology has been widely used in the treatment of diseases of otolaryngology, urology surgery, spinal surgery, gynecology and anorectal surgery at home and abroad, and has been proved to have good results with the characteristics of low temperature, safety and high efficiency.

[0005] A cold plasma jet is produced by ionizing working gas under atmospheric pressure by applying a high pressure. The cold plasma jet is generally composed of charged particles, free radicals, electrons and various active particles. The application of cold plasma in the biomedical field has attracted more and more attentions. Many researches have confirmed that the cold plasma jet can effectively inactivate various pathogenic microorganisms such as bacteria, fungi and viruses. Very good research results have been achieved in dental treatment, cosmetology, hemostasis, anti-inflammation, wound healing, skin disease treatment and tumor treatment. The cold plasma technology can be used as an auxiliary surgery, especially for tumor treatment. Since the plasma is ejected along with airflow, it is called a “plasma jet”, the plasma jet is approximate to room temperature, and can effectively inhibit proliferation and migration of tumor cells and induce apoptosis without damaging normal tissues.

[0006] At present, surgery is a main method for treating tumors, especially in intracranial tumor surgery, cutting and ablating tumor tissues by a low temperature plasma technology has been more and more widely used at present. In order to ensure normal tissues and functions such as nerves, blood vessels and the brain tissue, tumors will inevitably remain in low temperature plasma cutting and ablation surgery, thereby leading to a risk of an increase of tumor recurrence; in addition, bacteria may invade the brain during or after a operation, thereby resulting in postoperative intracranial infection. The cold plasma jet can induce apoptosis of residual tumor cells and inhibiting bacteria without damaging normal tissues, so the cold plasma technology can be used to assist in low temperature plasma cutting and ablation surgery.

[0007] The surgical instrument of the low temperature plasma technology 1s a plasma cutter head, and the surgical instrument of the cold plasma jet technology is a jet cutter head, however, power supplies used by the plasma cutter head and the jet cutter head are different; moreover, saline water is needed when the plasma cutter head is used, and an inert gas flow is needed when the jet cutter head is used, then supporting facilities for the plasma cutter head and the jet cutter head are also different. Therefore, the plasma cutter head and the jet cutter head can only be used on their own plasma energy systems, and two different plasma energy systems need to be equipped for one surgical operation, the use is inconvenient.

Summary

[0008] The present application provides a multifunctional plasma surgical system, and the multifunctional plasma surgical system integrates a low temperature plasma energy system and a cold plasma jet energy system. A low temperature plasma cutter head and a jet cutter head can be used on one device, cutting and ablation of tumor tissues by a plasma knife is realized, and apoptosis of residual tumor cells and bacteria inhibiting induced by a plasma jet is also realized. The multifunctional plasma surgical system is used conveniently, and medical resources and economic burden borne by patients are reduced.

[0009] Technical solutions provided by the present application are as follows:

[0010] A multifunctional plasma surgical system includes an AC mains interface, a DC power module, a plasma power module, a plasma jet power module, a plasma output interface, a plasma jet output interface, a main control module, a liquid flow control module, an airflow control module, a plasma cutter head and a jet cutter head, wherein:

[0011] the AC mains interface is connected with the DC power module, the plasma power module and the plasma jet power module are connected in parallel to the DC power module, a gating switch is arranged between the plasma power module and the plasma jet power module and the DC power module, the plasma output interface and the plasma jet output interface are connected to the plasma power module and the plasma jet power module, respectively, and the plasma cutter head and the jet cutter head are connected with the plasma output interface and the plasma jet output interface, respectively; and

[0012] the main control module is connected with the liquid flow control module, the airflow control module, the plasma power module and the plasma jet power module.

[0013] Further, the main control module is connected with a plasma control board and a plasma jet control board, and the plasma control board and the plasma jet control board are connected with the plasma power module and the plasma jet power module, respectively.

[0014] Further, the main control module is connected with a control switch and a display module, the control switch is a foot switch, and the foot switch includes two foot keys; the

AC mains interface is connected with an auxiliary circuit module, and the auxiliary circuit module is connected with the main control module.

[0015] Further, the main control module includes a processing unit, and the processing unit is connected with an auxiliary circuit module interface, a liquid flow control module interface, an airflow control module interface, a control switch state detection interface, a plasma cutter head detection interface, a display module interface, a function selection interface and a gear signal interface; and

[0016] the auxiliary circuit module interface, the liquid flow control module interface, the airflow control module interface, the control switch state detection interface and the display module interface are connected with the auxiliary circuit module, the liquid flow control module, the airflow control module, the control switch and the display module, respectively; the plasma cutter head detection interface is configured to be connected with the plasma cutter head, and the function selection interface and the gear interface are both connected with the plasma control board and the plasma jet control board.

[0017] Further, the gating switch is a single-pole double-throw DC contactor, the single-pole double-throw DC contactor is arranged at an output end of the DC power module and is connected with the main control module.

[0018] Further, the DC power module includes a power switch, a first filter unit, a full-bridge rectifier unit and a second filter unit, wherein the first filter unit is connected with the AC mains interface, the power switch is arranged between the first filter unit and the AC mains interface, the full-bridge rectifier unit is connected with an output of the first filter unit, and the second filter unit is connected with an output of the full-bridge rectifier unit.

[0019] Further, the plasma jet power module includes a half-bridge switch unit and a first voltage transformer unit, the half-bridge switch unit is connected with an output of the DC power module, the first voltage transformer unit is connected with an output of the half- bridge switch unit, and the half-bridge switch unit is connected with a first PWM controller configured to control the half-bridge switch unit.

[0020] Further, the plasma power module includes a third filter unit, a full-bridge switch unit and a second voltage transformer unit, wherein the third filter unit is connected with the output of the DC power module, the full-bridge switch unit is connected with an output of the third filter unit, the second voltage transformer unit is connected with an output of the full-bridge switch unit, and the full-bridge switch unit is connected with a second PWM controller configured to control the full-bridge switch unit.

[0021] Further, the plasma cutter head includes a plasma handle, a front end of the plasma handle is provided with a cutter bar assembly, the plasma handle is provided with a power line assembly, a water inlet pipe and a water suction pipe, the cutter bar assembly is internally provided with a working electrode, one end of the power line assembly is connected with the plasma output interface, the other end penetrates through the inside of the plasma handle 5 and is connected with the working electrode inside the cutter bar assembly, and one end of the water inlet pipe and one end of the water suction pipe are connected with the liquid flow control module, and the other end of the water inlet pipe and the other end of the water suction pipe penetrate through the inside of the plasma handle and the inside of the cutter bar assembly and reach the front end of the cutter bar assembly.

[0022] Further, the jet cutter head includes a plasma jet handle, a front end of the plasma jet handle is provided with a cutter head assembly, the plasma jet handle 1s provided with a power supply wiring, an air inlet pipe, and a negative pressure air suction pipe, wherein the cutter head assembly is internally provided with a high voltage electrode and a ground electrode, one end of the power supply wiring is connected with the plasma jet output interface, and the other end penetrates through the inside of the plasma jet handle and is connected with the high voltage electrode and the ground electrode, one end of the air inlet pipe is connected with the airflow control module, the other end penetrates through the plasma jet handle and is connected with a plasma channel in the cutter head assembly, one end of the negative pressure air suction pipe is connected with the airflow control module, and the other end penetrates through the plasma jet handle and is connected with a suction channel on an outer wall of the cutter head assembly.

[0023] Further, the cutter head assembly includes a tubular insulating outer wall, the insulating outer wall is internally provided with an insulating dielectric pipe, and the plasma channel is disposed inside the insulating dielectric pipe and penetrates through front and rear ends of the insulating dielectric pipe;

[0024] the high voltage electrode is a needle-shaped high voltage electrode, the ground electrode is an annular ground electrode, the needle-shaped high voltage electrode is arranged in the plasma channel of the insulating dielectric pipe, the annular ground electrode is sleeved on an outer wall of the insulating dielectric pipe, the annular ground electrode is located in front of the needle-shaped high voltage electrode, and a front end of the needle- shaped high voltage electrode is spaced from a rear end of the annular ground electrode by a set distance;

[0025] or, the high voltage electrode is an annular high voltage electrode, the ground electrode is an annular ground electrode, the annular high voltage electrode and the annular ground electrode are sleeved on the outer wall of the insulating dielectric pipe, the annular ground electrode is located in front of the annular high voltage electrode, and the front end of the annular high voltage electrode is spaced from the rear end of the annular ground electrode by a set distance.

[0026] The present application has the following beneficial effects:

[0027] The multifunctional plasma surgical system of the present application integrates a low temperature plasma energy system and a cold plasma energy system, therefore, a low temperature plasma cutter head and a jet cutter head can be used on one device, cutting and ablation of tumor tissues by a plasma knife is realized, and apoptosis of residual tumor cells and bacteria inhibiting induced by a plasma jet is also realized. The multifunctional plasma surgical system is used conveniently, and medical resources and economic burden borne by patients are reduced.

Brief Description of the Drawings

[0028] Fig. 1 is a schematic diagram of a multifunctional plasma surgical system of the present application;

[0029] Fig. 2 is a schematic diagram showing connection among a DC power module, a plasma power module and a plasma jet power module;

[0030] Fig. 3 is a schematic diagram of a main control module;

[0031] Fig. 4 is a schematic diagram of a plasma cutter head;

[0032] Fig. 5 is a schematic diagram of one example of a jet cutter head,

[0033] Fig. 6 is a schematic diagram of an internal structure of the jet cutter head shown in

Fig. 5;

[0034] Fig. 7 is a schematic diagram of another example of a jet cutter head,

[0035] Fig. 8 is a schematic diagram of an internal structure of the jet cutter head shown in

Fig. 7;

[0036] Fig. 9 and Fig. 10 show effects of plasma jet treatment under different conditions on activity of rat pituitary tumor cells;

[0037] Fig. 11 shows effects of plasma jet treatment on apoptosis of rat pituitary tumor cells;

[0038] Fig. 12 shows effects of plasma jet treatment on the cycle of rat pituitary tumor cells.

Detailed Description

[0039] In order to make the technical problems, technical solutions and advantages to be solved by the present application clearer, a detailed description will be given below in combination with accompanying drawings and specific embodiments.

[0040] The present application provides a multifunctional plasma surgical system, as shown in Figs. 1-12, the multifunctional plasma surgical system includes an AC mains interface 1, a DC power module 2, a plasma power module 3, a plasma jet power module 4, a plasma output interface 5, a plasma jet output interface 6, a main control module 7, a liquid flow control module 8, an airflow control module 9, a plasma cutter head 10 and a jet cutter head 11, wherein:

[0041] the AC mains interface 1 is connected with the DC power module 2, the AC mains interface 1 receives single-phase 220V AC mains power and supplies to the DC power module 2, and the DC power module 2 converts the 220V AC mains power into DC power and outputs the DC power.

[0042] The plasma power module 3 and the plasma jet power module 4 are connected in parallel to the DC power module 2, and the DC power module 2 provides DC power to the plasma power module 3 and the plasma jet power module 4. The plasma output interface 5 and the plasma jet output interface 6 are connected to the plasma power module 3 and the plasma jet power module 4, respectively, and the plasma cutter head 10 and the jet cutter head 11 are connected to the plasma output interface 5 and the plasma jet output interface 6, respectively.

[0043] The plasma power module 3 receives the DC supplied by the DC power module 2 and outputs an adjustable 100kHz high frequency AC signal to the plasma output interface for use by the plasma cutter head 10. The plasma jet power module 4 receives the DC supplied by the DC power module 2, and outputs the SkHz-30kHz high frequency AC signal to the plasma jet output interface 6 for use by the jet cutter head 11. 5 [0044] A gating switch 39 is arranged between the plasma power module 3 and the plasma jet power module 4 and the DC power module 2. The gating switch is configured to switch between the plasma power module 3 and the plasma jet power module 4. The gating switch is in an alternative mode. The plasma power module 3 and the plasma jet power module 4 can work independently but cannot work simultaneously

[0045] The main control module 7 is directly or indirectly connected with the liquid flow control module 8, the airflow control module 9, the plasma power module 3 and the plasma jet power module 4, and the work of each corresponding module is controlled by the main control module 7. After the main control module 7 works, the main control module 7 directly adjusts the working states of the liquid flow control module 8 and the airflow control module 9 and indirectly adjusts the working states of the plasma power module 3 and the plasma jet power module 4 according to control instructions, and finally outputs the energy to the plasma cutter head 10 or the jet cutter head 11.

[0046] The plasma power module 3 is connected with the power line assembly of the plasma cutter head 10 through the plasma output interface 5, to supply power to the plasma cutter head 10. The liquid flow control module 8 controls the on-off and flow rate of the normal saline supplied to the plasma cutter head 10, to realize the use of the plasma cutter head 10.

[0047] The plasma jet power module 4 is connected with a power line of the jet cutter head 11 through the plasma jet output interface 6, to supply power to the jet cutter head 11. The airflow control module 9 controls the on-off and flow rate of the inert gas supplied to the jet cutter head 11, to realize the use of the jet cutter head 11.

[0048] The airflow control module 9 can adopt a gas flow controller, the gas flow controller adjusts the flow rate to be in a range of 1-3slm. A digital display function is available through the control of a pneumatic solenoid valve, and the flow rate is adjusted by a rotary knob.

[0049] The multifunctional plasma surgical system of the present application integrates a low temperature plasma energy system and a cold plasma jet energy system. A low temperature plasma cutter head 10 and a jet cutter head 11 can be used on one device, thereby not only realizing cutting and ablation of tumor tissues by a plasma knife, but also realizing apoptosis of residual tumor cells and bacteria inhibiting induced by the plasma jet. The multifunctional plasma surgical system is used conveniently, and medical resources and economic burden borne by patients are reduced.

[0050] At present, although some theoretical researches and developments on the cold plasma technology have been available, there are still no reports on the application of cold plasma in skull base tumors such as pituitary tumors. Because of particularity of skull base anatomy, skull base tumors often penetrate through important blood vessels and nerves of the skull base, and invade and surround important structures of the skull base, so complete resection of turners is difficult, and residual tumors are prone to recurrence. In the present application, the cold plasma is applied to the skull base tumors such as pituitary tumors.

After tumors are resected by a low temperature plasma, the cold plasma technology is used to treat tumors which may remain on important blood vessels and nerve surface of the skull base, then normal tissues will not be damaged while apoptosis of the residual tumor cells and bacteria inhibiting is induced, thereby improving the resection efficiency of tumors, and at the same time effectively reducing recurrence of tumors and postoperative infection.

[0051] As an improvement of embodiments of the present application, the main control module 7 is connected with a plasma control board 13 and a plasma jet control board 14.

The plasma control board 13 and the plasma jet control board 14 are connected with the plasma power module 3 and the plasma jet power module 4, respectively.

[0052] The main control module 7 may also be connected with a control switch 12 and a display module 15.

[0053] The control switch 12 may be a foot switch. The foot switch includes a left and a right foot key. When the plasma power module 3 works, the left foot key and the right foot key correspond to the control of the ablation and cutting functions and the coagulation and hemostasis functions, respectively. When the plasma jet power module 4 works, the left foot key is blank and the right foot key controls the start or stop.

[0054] The foot switch 12 provides signals of switching value to the main control module 7 for sampling. The main control module 7 acquires a state signal of the foot switch for judgment, and executes set actions for a specific state according to a program set by the software.

[0055] The ablation and cutting gear of the plasma power module 3 is adjusted to 0-50 gears, the coagulation and hemostasis gear is adjusted to -50 gear. Gear adjustment is realized by the main control module 7. The main control module 7 respectively provides control signals of 50 gears, and the signal corresponds to an output power.

[0056] The gear can be set through the display module 15. The display module 15 adopts the form of a touch screen, and the display interface can be used as an input adjustment interface.

[0057] The main control module 7 can communicate with the display module 15. The size of the gear set on the display module 15 determines the size of the control signal of the main control module 7, and the size of the control signal further affects the output of PWM waves, thereby generating different power outputs. The control signal is provided to the plasma control board 13, and the plasma control board 13 generates a PWM wave to control the output of the plasma power module 3.

[0058] The control signal is a voltage signal, and is generally 0-5V. The change of this control signal can lead to a change of a duty cycle of the PWM wave, to further change the output of the plasma power module 3. The main control module 7 receives a gear signal and gives the gear signal to a single chip microcomputer on the main control module 7. The single chip microcomputer gives different signals of 0-5V to a generation circuit according to internal programmable programs to generate different control signals.

[0059] The frequency of the plasma jet power module 4 ranges from 5kHz to 30kHz, preferably 5kHz with a sine wave output, and the voltage peak is 10kV. The power adjustment gears are in 50 gears, and the main control module 7 provides control signals of gears, and the signals correspond to the output power. The control of different gears of the plasma jet power module 4 is similar to that of the plasma power module 3, and will not be repeated redundantly herein.

[0060] The main control module 7 and its attached modules of the present application can be powered by an additional power supply, and the main control module 7 can also be powered by the AC mains power of the AC mains interface 1 through an auxiliary circuit module 16. At this time, the AC mains interface 1 is connected with the auxiliary circuit module 16, and the auxiliary circuit module 16 is connected with the main control module 7.

[0061] The aforementioned DC power module 2 includes a power switch 17, a first filter unit 18, a full-bridge rectifier unit 19 and a second filter unit 20, wherein the first filter unit 18 is connected with an AC mains interface 1, and a power switch 17 is arranged between the first filter unit 18 and the AC mains interface 1, the full-bridge rectifier unit 19 is connected with the output of the first filter unit 18, and the second filter unit 20 is connected with the output of the full-bridge rectifier unit 19. The first filter unit 18 may be a common mode inductor, and the second filter unit 20 may be a filter capacitor.

[0062] The DC power module 2 controls the on and off through a power switch 17, and then current reaches a first filter unit 18, the first filter unit 18 is equivalent to an EMI filter, to enhance the anti-interference capability of the power supply, and then current reaches a full- bridge rectifier unit 19. Finally, the DC is more stable after being rectified and filtered by a second filter unit 20.

[0063] The aforementioned gating switch is a single-pole double-throw DC contactor, the single-pole double-throw DC contactor is arranged at an output end of the DC power module 2 and is connected with the main control module 7. The output switching problem of the DC power module 2 is mainly realized by superimposing the following two measures:

[0064] 1. The main control module 7 controls coils of the single-pole double-throw DC contactor through instructions to realize output switching of the DC power module 2.

[0065] 2. When switching to a certain power output, for example, switching to the plasma power module 3, the main control module 7 gives a start instruction, and the plasma control board 13 starts to provide a PWM waveform to start working, otherwise, the plasma control board 13 stops outputting the PWM wave and stops working.

[0066] Output switching of the DC power module 2 can be truly realized only when the above two points are satisfied at the same time.

[0067] The main control module 7 of the present application includes a processing unit 21, the processing unit 21 is a signal receiving and processing system composed of a single chip microcomputer and some auxiliary circuits. The processing unit 21 is connected with an auxiliary circuit module interface 22, a liquid flow control module interface 23, an airflow control module interface 24, a control switch state detection interface 25, a plasma cutter head detection interface 26, a display module interface 27, a function selection interface 28, a gear signal interface 29, a sound size adjustment interface 30 and a sound output interface 31.

[0068] The auxiliary circuit module interface 22, the liquid flow control module interface 23, the airflow control module interface 24, the control switch state detection interface 25 and the display module interface 27 are connected with the auxiliary circuit module 16, the liquid flow control module 8, the airflow control module 9, the control switch 12 and the display module 15, respectively. The control switch state detection interface 25 and the control switch signal interface 26 are connected with the control switch 12. The plasma cutter head detection interface 26 is connected with the plasma cutter head 10 to detect the state of the plasma cutter head 10.

[0069] The function selection interface 28 and the gear signal interface 29 are both connected with the plasma control board 13 and the plasma jet control board 14, the function selection interface 28 is configured to gate the plasma control board 13 or the plasma jet control board 14, and the gear signal interface 29 is configured to send gear control signals to the plasma control board 13 or the plasma jet control board 14.

[0070] A sound size adjustment interface 30 and a sound signal output interface 31 are configured to connect a loudspeaker and output sound prompts.

[0071] The main control module 7 has a built-in upgradeable software program, and by modifying the settings on the display module 15, the programming of the functions of the above interfaces can be adjusted.

[0072] The high frequency AC signal provided by the plasma jet power module of SkHz- 30kHz of the present application is used by the jet cutter head 11 to work. In the present application, the specific form of the plasma jet power module 4 is not limited. In one of the examples, the plasma jet power module 4 includes a half-bridge switch unit 32 and a first voltage transformer unit 33, the half-bridge switch unit 32 is connected with an output of the

DC power module 2 (that is, connected with an output of the second filter unit 20), the first voltage transformer unit 33 is connected with the output of the half-bridge switch unit 32, and the half-bridge switch unit 32 is connected with a first PWM controller 34 which is configured to control the half-bridge switch unit 32.

[0073] The half-bridge switch unit 32 receives the DC power supply provided by a previous- stage DC power module 2, and the half-bridge switch unit 32 is controlled by the first PWM controller 34 simultaneously, to realize switching actions in an orderly manner according to specific on-off logics, and output high frequency AC signals. The first voltage transformer unit 33 mainly includes a high frequency transformer, and the high frequency transformer supplies the regulated high frequency signals to the jet cutter head 11 through the plasma jet output interface 6.

[0074] The first PWM controller 34 may be located in the plasma jet control board 14, and the first PWM controller 34 of the plasma jet control board 14 is controlled by the main control module 7.

[0075] The plasma power module 3 of the present application provides an adjustable signal of 100kHz to match the work of different plasma cutter heads 10. In the present application, the specific form of the plasma power module 3 is not limited. In one of the examples, the plasma power module 3 includes a third filter unit 35, a full-bridge switch unit 36 and a second voltage transformer unit 37, wherein the third filter unit 35 is connected with the output of the DC power module 2 (i.e, connected with the output of the second filter unit 20), the full-bridge switch unit 36 is connected with the output of the third filter unit 35, and the second voltage transformer unit 37 is connected with the output of the full-bridge switch unit 36, and the full-bridge switch unit 36 1s connected with a second PWM controller 38 which is configured to control the full-bridge switch unit 36.

[0076] The third filter unit 35 receives the DC power supply provided by the previous-stage

DC power module 2, performs filtering and anti-interference processing, and then provides to the full-bridge switch unit 36. The full-bridge switch unit 36 is controlled by the second

PWM controller 38, to realize switching actions in an orderly manner according to specific on-off logics, and output high frequency AC signals and provide to the second voltage transformer unit 37, and the second voltage transformer unit 37 provides the regulated high frequency signal to the plasma cutter head 10 through the plasma output interface 5.

[0077] The third filter unit 35 may be a common mode inductor, the second voltage transformer unit 37 may be a high frequency transformer, and the second PWM controller 38 may be located in the plasma control board 13, and the second PWM controller 38 of the plasma control board 13 is controlled by the main control module 7.

[0078] In the present application, the form of the plasma cutter head 10 is not limited. In one of the examples, as shown in Fig. 4, the plasma cutter head 10 includes a plasma handle 39, a front end of the plasma handle 39 is provided with a cutter bar assembly 40, the plasma handle 39 is provided with a power line assembly 41, a water inlet pipe 42 and a water suction pipe 43, wherein a front end of the cutter bar assembly 40 is provided with a working electrode 44, one end of the power line assembly 41 is connected with the plasma output interface 5, the other end penetrates through the inside of the plasma handle 39 and the inside of the cutter bar assembly 40 to be connected with the working electrode 44, and one end of the water inlet pipe 42 and one end of the water suction pipe 43 are connected with the liquid flow control module 8, and the other end of the water inlet pipe 42 and the other end of the water suction pipe 43 penetrate through the inside of the plasma handle 39 and the inside of the cutter bar assembly 40 and reach the front end of the cutter bar assembly 40.

[0079] Normal saline enters the inside of the plasma cutter head 10 through the water inlet pipe 42 of the plasma cutter head 10 and reaches the front end, the liquid flow control module 8 controls the on-off and flow rate of the normal saline. The plasma output interface 5 supplies power to the working electrode 44 through the power line assembly 41. Na*, CL",

H* and OH in the normal saline are excited through the current of the working electrode 44, to form plasma. The water suction pipe 43 sucks away the surgically resected tissues and fluid together.

[0080] In the present application, the form of the jet cutter head 11 is not limited. In one of the examples, as shown in Figs. 5-8, the jet cutter head 11 includes a plasma jet handle 45, a front end of the plasma jet handle 45 is provided with a cutter head assembly 46, the plasma jet handle 45 is provided with a power supply wiring 47, an air inlet pipe 48 and a negative pressure air suction pipe 49. The cutter head assembly 46 is internally provided with a high voltage electrode 50 or 50° and a ground electrode 51, one end of the power supply wiring 47 is connected with the plasma jet output interface 6, and the other end penetrates through the inside of the plasma jet handle 45, two groups of wires of the power supply wiring 47 are connected with the high voltage electrode 50 or 50° and the ground electrode 51, respectively, one end of the air inlet pipe 48 is connected with the airflow control module 9, and the other end penetrates through the plasma jet handle 45 and is connected with the plasma channel 52 inside the cutter head assembly 46, one end of the negative pressure air suction pipe 49 is connected with the airflow control module 9, and the other end penetrates through the plasma jet handle 45 and 1s connected with a suction channel 53 on an outer wall of the cutter head assembly 46.

[0081] The inert gas enters the plasma channel 52 inside the jet cutter head 11 through the air inlet pipe 48 of the jet cutter head 11, the airflow control module 9 controls the on-off and flow rate of the inert gas, the plasma jet output interface 6 supplies power to the high voltage electrode 50, 50’ through the power supply wiring 47, the inert gas is ionized under the high pressure of the high voltage electrode 50, 50’, to generate cold plasma and eject along with the airflow to form a plasma jet. Exhaust gas during surgery is discharged through the suction channel 53 and the negative pressure air suction pipe 49.

[0082] In the present application, the cutter head assembly 46 includes a tubular insulating outer wall 54, the insulating outer wall 54 is internally provided with an insulating dielectric pipe 55, and a front end of the insulating dielectric pipe 55 protrudes from a front end of the insulating outer wall 54 by a set distance. The plasma channel 52 is formed in the insulating dielectric pipe 55 and penetrates through the front and rear ends of the insulating dielectric pipe 55. The plasma jet handle 45 is internally provided with a handle cavity 61, a rear end of the cutter head assembly 46 is inserted into a front end of the handle cavity 61 from a front end of the plasma jet handle 45. The suction channel 53 is arranged outside the insulating outer wall 54, and the front end of the suction channel 53 is arranged in the rear of the front end of the insulating dielectric pipe 55 by a certain distance, and the front and rear of the suction channel 53 are penetrated. The power supply wiring 47, the air inlet pipe 48 and the negative pressure air suction pipe 49 are arranged at a rear end of the plasma jet handle 45, and the high voltage wire 56 and the ground wire 57 of the power supply wiring 47 are connected with the needle-shaped high voltage electrode 50 and the annular ground electrode 51, respectively.

[0083] In the present application, the specific structural form of the high voltage electrode 50, 50’ is not limited. In one of the examples, as shown in Fig. 5 and Fig. 6, the high voltage electrode is an annular high voltage electrode 50, and the ground electrode is an annular ground electrode 51, the annular high voltage electrode 50 and the annular ground electrode 51 are sleeved on an outer wall of the insulating dielectric pipe 55, the annular ground electrode 51 is located in front of the annular high voltage electrode 50, and the front end of the annular high voltage electrode 50 is spaced from the rear end of the annular ground electrode 51 by a set distance, and the distance can be 0.5-1.5cm, and the distance between the front end of the annular ground electrode 51 and the front end of the insulating dielectric pipe 551s 0.5-1.5cm.

[0084] Corresponding to the above-mentioned annular high voltage electrode 50 and the annular ground electrode 51, the insulating outer wall 54 includes a first insulating pipe 58 and a second insulating pipe 59, and the insulating dielectric pipe 55 is located inside the first insulating pipe 58, and a front end of the insulating dielectric pipe 55 protrudes from the front end of the first insulating pipe 58 by a set distance, and the annular ground electrode 51 is located on the insulating dielectric pipe 55 in front of the first insulating pipe 58.

[0085] The periphery of the front end of the insulating dielectric pipe 55 and the periphery of the front end of the annular ground electrode 51 are provided with a circle of insulating filling structure 60, and the insulating filling structure 60 enables the front end of the cutter head assembly 46 to be of a tapered structure. The second insulating pipe 59 is coated outside the first insulating pipe 58 and the insulating filling structure 60, and the front end of the insulating dielectric pipe 55 protrudes from the front end of the second insulating pipe 59 by a set distance.

[0086] The first insulating pipe 58, the second insulating pipe 59 and the insulating filling structure 60 are configured to fix the insulating dielectric pipe 55 and configured for insulating protection, the insulating outer wall 54, the insulating dielectric pipe 55, the first insulating pipe 58 and the second insulating pipe 59 are all round tubular structures, and the insulating filling structure 60 is a conical structure as a whole, and a cylindrical cavity is formed inside the conical structure, and the conical structure is sleeved on the periphery of the front end of the insulating dielectric pipe 55 through the cylindrical cavity.

[0087] Preferably, the second insulating pipe 59 is a heat shrinkable pipe, and the second insulating pipe 59 is coated outside the first insulating pipe 58 and the insulating filling structure 60 in a heat shrinkable manner. When the second insulating pipe 59 is set, the second insulating pipe 59 is sleeved outside the first insulating pipe 58 and the insulating filling structure 60, and then the second insulating pipe 59 is heated. Due to the nature of the heat shrinkable pipe, the second insulating pipe 59 produces irreversible shrinkage, and tightly coats the first insulating pipe 58 and the insulating filling structure 60, and the second insulating pipe 59 will not recover reversibly after cooling, but will be kept in a contracted state.

[0088] The power supply wiring 47 is connected to the rear end of the plasma jet handle 45, the power supply wiring 47 enters the handle cavity 17 from the rear end of the plasma jet handle 45 and penetrates forwards to the front end of the handle cavity 17, and the high voltage wire 56 of the power supply wiring 47 penetrates in a space between the insulating dielectric pipe 55 and the first insulating pipe 58 and is connected with the annular high voltage electrode 50, the ground wire 57 of the power supply wiring 47 penetrates through a gap between the first insulating pipe 58 and the second insulating pipe 59 and is connected with the annular ground electrode 51.

[0089] The air inlet pipe 48 is connected to a rear end of the plasma jet handle 45, the air inlet pipe 48 enters inside the handle cavity 61 from the rear end of the plasma jet handle 45 and penetrates forwards to the front end of the handle cavity 61, and the front end of the air inlet pipe 46 is connected with the rear end of the plasma channel 52 of the insulating dielectric pipe 55 through the air inlet channel 62.

[0090] The negative pressure air suction pipe 49 is connected to the rear end of the plasma jet handle 45, and the negative pressure air suction pipe 49 enters inside the handle cavity 61 from the rear end of the plasma jet handle 45 and penetrates forwards to the front end of the handle cavity 61, and the front end of the negative pressure air suction pipe 49 is connected with the rear end of the suction channel 53.

[0091] For fixing the insulating dielectric pipe and for sealing, a space between the first insulating pipe 58, the second insulating pipe 59 and the insulating filling structure 60 and the insulating dielectric pipe 55 and the air inlet channel 62 is filled with a sealant 63.

[0092] The annular high voltage electrode 50 and the annular ground electrode 51 are made of solid metals, including but not limited to aluminum, copper, stainless steel, tungsten and their alloys. The insulating dielectric pipe is made of ceramic or glass. The first insulating pipe and the insulating filling structure are made of ceramics, including but not limited to alumina ceramics, zirconia ceramics, and the like. The second insulating pipe is made of heat shrinkable materials, including but not limited to polyvinylidene fluoride, PET, or PVC and the like. The suction channel and the air inlet channel are made of polymer materials, including but not limited to PEEK, PI, PVC and the like. The material of the sealant is epoxy resin structural adhesive.

[0093] In another example, as shown in Fig. 7 and Fig. 8, the high voltage electrode is a needle-shaped high voltage electrode 50°, and the ground electrode is an annular ground electrode 51, and the needle-shaped high voltage electrode 50° is arranged in the plasma channel 52 of the insulating dielectric pipe 55, the annular ground electrode 51 is sleeved on the outer wall of the insulating dielectric pipe 55, the annular ground electrode 51 1s located in front of the needle-shaped high voltage electrode 50°, and the front end of the needle- shaped high voltage electrode 50’ is spaced from the rear end of the annular ground electrode 51 by a set distance, the distance can be 0.5-1.5cm, and the distance between the front end of the annular ground electrode and the front end of the insulating dielectric pipe is 0.5- 1.5cm.

[0094] Corresponding to the above-mentioned needle-shaped high voltage electrode 50° and the annular ground electrode 51, the insulating outer wall 54 includes a first insulating pipe 58’ and a second insulating pipe 59°, the insulating dielectric pipe 55 is located inside the first insulating pipe 58’, the front end of the insulating dielectric pipe 55 protrudes from the front end of the first insulating pipe 58’ by a set distance, and the annular ground electrode 51 is located on the insulating dielectric pipe 55 in front of the first insulating pipe 58°. The second insulating pipe 59’ is coated outside the first insulating pipe 58, and the front end of the insulating dielectric pipe 55 protrudes from the front end of the second insulating pipe 59’ by a first distance.

[0095] A tubular insulating structure 60° is arranged between the insulating dielectric pipe 55 in front of the annular ground electrode 51 and the second insulating pipe 59°, the front end of the tubular insulating structure 60° protrudes from the front end of the second insulating pipe 59° by a set distance, and the front end of the tubular insulating structure 60° is located behind the front end of the insulating dielectric pipe 55 by a certain distance.

[0096] The first insulating pipe 58’, the second insulating pipe 59’ and the tubular insulating structure 60° are configured to fix the insulating dielectric pipe 55 and configured for insulating protection. The insulating outer wall 54, the insulating dielectric pipe 55, the first insulating pipe 58°, the second insulating pipe 59’ and the tubular insulating structure 60’ are all tubular structures.

[0097] For fixing the insulating dielectric pipe 55 and for filling seal, the insulating dielectric pipe 55 and the first insulating pipe 58’ are sealed and bonded by a first sealant, and the insulating dielectric pipe 55 and the second insulating pipe 59° are sealed and filled by a second sealant.

[0098] The power supply wiring 47 is connected to the rear end of the plasma jet handle 45, the power supply wiring 47 enters inside the handle cavity 61 from the rear end of the plasma jet handle 45 and penetrates forwards to the front end of the handle cavity 61, the rear end of the first insulating pipe 58’ is provided with a sealing plug 64, the needle-shaped high voltage electrode 50° penetrates on the sealing plug 64 for fixing, and the front end and the rear end of the needle-shaped high voltage electrode 50° are respectively located on the front and rear sides of the sealing plug 64. The high voltage wire 56 of the power supply wiring

47 is connected to the rear end of the needle-shaped high voltage electrode 50° through a connection terminal 65. The ground wire 57 of the power supply wiring 47 penetrates through the gap between the first insulating pipe 58” and the second insulating pipe 59° and is connected with the annular ground electrode 51.

[0099] The air inlet pipe 48 1s connected to the rear end of the plasma jet handle 45, the air inlet pipe 48 enters inside the handle cavity 61 from the rear end of the plasma jet handle 45 and penetrates forwards to the front end of the handle cavity 61, the first insulating pipe 58’ is internally provided with an air cavity 67, a rear end of the plasma channel 52 of the insulating dielectric pipe 55 is communicated with the air cavity 67, the front end of the air inlet pipe 48 is provided with an air inlet cannula 66, and the air inlet cannula 66 penetrates through the sealing plug 64 and is communicated with the air cavity 67.

[0100] The negative pressure air suction pipe 49 is connected to the rear end of the plasma jet handle 45, the negative pressure air suction pipe 49 enters inside the handle cavity 61 from the rear end of the plasma jet handle 45 and penetrates forwards to the front end of the handle cavity 61, and the front end of the plasma jet handle 45 is connected with the rear end of the suction channel 53.

[0101] The needle-shaped high voltage electrode 6 and the annular ground electrode 7 are made of solid metals, including but not limited to stainless steel, tungsten and their alloys.

The insulating dielectric pipe is made of ceramic or glass. The first insulating pipe, the second insulating pipe and the tubular insulating structure are made of ceramics or plastics, including but not limited to alumina ceramics, zirconia ceramics, polyvinylidene fluoride,

PVC pipes, PET and the like. The suction channel and the air inlet cannula are made of polymer materials, including but not limited to PEEK, PI, PVC, etc. The sealing plug is made of soft materials, including but not limited to medical silicone, medical polyurethane, and medical rubber. The connection terminal is made of solid metals, including but not limited to aluminum, copper and their alloys. The material of the first sealant and the second sealant is epoxy resin structural adhesive.

[0102] The inhibitory effects of plasma jet (i.e., the jet cutter head) on tumor cells are verified below through specific test examples of rat pituitary tumor GH3 cell line:

[0103] 1. GH3 cells were cultured in a DMEM/F12K+10% FBS medium, grew to a logarithmic phase and were then subcultured into a 6-well plate and a 96-well plate at a density of 10000/well and 250000/well, respectively. The CH3 cells were cultured continuously for 24 hours for plasma treatment.

[0104] 2. 99.999% helium was taken as a working gas at a flow rate of 1400sccm, sinusoidal

AC voltage excitation was performed at 5.6kV, SkHz and 5.6kV, 30kHz, respectively, to discharge and generate a plasma jet, GH3 cells were treated, and after treatment, GH3 cells were cultured continuously for 24 hours in a replaced medium.

[0105] 3. Cell activity was detected by a CCK-8 method, and results are shown in Fig. 9 and

Fig. 10. In Fig. 9, the voltage Vpp of the high voltage electrode is equal to 5.6kV, the frequency f is equal to 30kHz, and the flow rate of helium is equal to 1400sccm, and in Fig. 10, the voltage Vpp of the high voltage electrode is equal to 5.6kV, the frequency f is equal to SkHz, and the flow rate of helium is equal to 1400sccm. It can be known from Fig. 9 and

Fig. 10 that, the plasma jet has an obvious inhibitory effect on rat pituitary tumor GH3 cell line. Wherein in Fig. 9 and Fig. 10, a horizontal coordinate shows the treatment time of cold plasma (0sT60s), and a vertical coordinate shows the relative cell activity of GH3 cells in each group relative to the control group without treatment (0s). The higher the corresponding value is, the better the cell activity is. The results showed that the cold plasma produced by discharges at two frequencies (30kHz and SkHz) with an increase of treatment time could effectively inhibit the activity of GH3 cells, and almost all the GH3 cells could be killed only after treatment for about 10s. Considering that the plasma produced by discharging at 5kHz is milder, SkHz is preferably a major treatment parameter of a jet cutter head.

[0106] 4. In normal living cells, phosphatidylserine (PS) was only distributed inside double layers of a cell membrane lipid, but the PS in a cell membrane turned from inside to outside during apoptosis of cells. A phospholipid binding protein V (Annexin V) is a calcium- dependent phospholipid binding protein, and has a high affinity with PS, therefore, the phospholipid binding protein V can bind to cell membranes of cells during an early phase of apoptosis through phosphatidylserine exposed outside the cells.

[0107] Therefore, by labeling Annexin V with fluorescein (such as FITC, EGFP, etc.) and using the labeled Annexin V as a fluorescent probe, the PS which turned to the outside of cell membranes is detected, and occurrence of cell apoptosis can be detected by a fluorescence microscope or a flow cytometry, which can be used as one of the indexes to detect early apoptosis of cells. Propidium iodide (PI) is a type of nucleic acid dye, and cannot penetrate through cell membranes of normal living cells. But for necrotic cells and cells during late phase of apoptosis, the cell membranes are destroyed and are not intact. The PI can penetrate through the cell membranes and make the nucleus red. According to the difference of intracellular fluorescence, necrotic cells and cells during a late phase of apoptosis can be distinguished from living cells and cells during an early phase of apoptosis.

Therefore, Annexin V can be used in combination with PI to distinguish cells in different phases of apoptosis.

[0108] In the present application, after the GH3 cells in the orifice plate were treated by a jet cutter head (the treatment conditions are as follows: the voltage Vpp is equal to 5.6kV, the frequency f is equal to 5kHz, the flow rate of helium is equal to 1400sccm), the cells were continuously cultured for 24 hours and then collected, and after cells were stained by

Annexin V-FITC/PL the apoptosis rate of cells was detected by a flow method. The results are as shown in Fig. 11, the upper left quadrant shows necrotic cells (Annexin V-negative/PI- positive), the upper right quadrant shows cells at a late phase of apoptosis (Annexin V- positive/PI-positive), the lower left quadrant shows living cells (Annexin V-negative/PI- positive), and the lower right quadrant shows cells at an early phase of apoptosis (Annexin

V-positive/Pl-negative). It can be known from Fig. 11 that, plasma jet treatment obviously increases apoptosis of GH3 cells, and the apoptosis rate of cells reaches 41%.

[0109] 5. Analysis of cell cycles by flow cytometry is based on contents of DNA in cells (horizontal coordinate), to count the number of cells with different contents of DNA (vertical coordinate), and calculate the proportion of such cells in the total number of cells. When cells are in G1 phase, DNA replication has not yet started, and the content of DNA 1s also the least, that is, the first peak of a flow detection result diagram. After cells enter an S phase, cells begin to replicate to complete replication, which is a process from once of DNA to twice of DNA, and the period span is particularly large in the flow analysis result diagram

(the second peak which is not high but wide), when cells complete DNA replication, cells enter the G2 phase. At this time, within the time period from completion of DNA replication in cells to DNA division, the cell contains twice as much DNA, which is the second peak in the flow result diagram. However, when cells are in an M phase, there are also twice as much

DNA in the cells, and the method using the DNA content cannot be separated from the G2 phase, so it is usually expressed as a G2/M phase on the flow result diagram.

[0110] In the present application, after the GH3 cells in the orifice plate were treated by a jet cutter head (the treatment conditions are as follows: the voltage Vpp is equal to 5.6kV, the frequency f is equal to 30kHz, and the flow rate of helium is equal to 1400sccm), the cells were continuously cultured for 24 hours and then collected and stained by a cell cycle detection kit. The cell cycle changes were detected by a flow cytometry. The results are as shown in Fig. 12. It can be known from Fig. 12 that the ratio of cells in a G2 phase of GH3 after plasma jet treatment is obviously increased, indicating that cells are blocked in the

G2/M phase.

[0111] The above is preferred embodiments of the present application. It should be noted that a number of modifications and embellishments can be made by those skilled in the art without departing from the principles of the present application. These modifications and embellishments should also be considered to fall within the protection scope of the present application.

Claims

CONCLUSIONS

1. Multi-function plasma surgical system comprising an AC power interface, a DC power module, a plasma power module, a plasma jet power module, a plasma output interface, a plasma jet output interface, a main control module, a fluid flow control module, an air flow control module, a plasma cutting head and a jet cutting head, wherein: the AC interface is connected to the DC power module, the plasma power module and the plasma jet power module are connected in parallel to the DC module, a gating switch is provided between the plasma power module and the plasma jet power module and the DC module, the plasma output interface and the plasma jet output interface are connected to the plasma power module and the plasma jet power module respectively, and the plasma cutting head and the jet cutting head respectively are connected to the plasma output interface and the plasma jet output interface; and the main control module is connected to the liquid flow control module, the air flow control module, the plasma power module and the plasma jet power module.

The multifunctional plasma surgical system according to claim 1, wherein the main control module is connected to a plasma control card and a plasma jet control card, and the plasma control card and the plasma jet control card are connected to the plasma power module and the plasma jet power module, respectively.

The multifunctional plasma surgery system of claim 2, wherein the main control module is connected to a control switch and a display module, the control switch is a foot switch and the foot switch includes two foot keys, the AC interface is connected to an auxiliary circuit module, and the auxiliary circuit module is connected to the main control module.

4. The multifunctional plasma surgical system according to claim 2, wherein the main control module includes a processing unit and the processing unit includes an auxiliary circuit module interface, a fluid flow control module interface, an air flow control module interface, a control switch state detection interface, a plasma cutting head detection interface, a display module interface, a function selection interface and a gear signal interface is connected; and the auxiliary circuit module interface, the liquid flow control module interface, the air flow control module interface, the control switch condition detection interface and the display module interface are connected to the auxiliary circuit module, the liquid flow control module, the air flow control module, the control switch and the display module respectively; the plasma cutter head sensing interface is configured to be connected to the plasma cutter head, and the function selection interface and the gear interface are both connected to the plasma control board and the plasma jet control board.

The multifunctional plasma surgery system of claim 2, wherein the gating switch is a single pole two-way DC switch, the single pole two-way DC switch is located at the output end of the DC module and connected to the main control module.

The multifunctional plasma surgical system according to claim 2, wherein the direct current power module includes a power switch, a first filter unit, a full bridge rectifier unit and a second filter unit, the first filter unit is connected to the alternating current interface, the power switch is arranged between the first filter unit and the alternating current interface , the full bridge rectifier unit is connected to an output of the first filter unit and the second filter unit is connected to an output of the full bridge rectifier unit.

The multifunctional plasma surgery system according to claim 6, wherein the plasma jet power module includes a half-bridge switch unit and a first voltage converter unit, the half-bridge switch unit is connected to an output of the DC power module, the first voltage converter unit is connected to an output of the half-bridge switch unit connected and the half-bridge switch unit is connected to a first PWM controller configured to control the half-bridge switch unit.

The multifunctional plasma surgical system according to claim 6, wherein the plasma power module includes a third filter unit, a full bridge switch unit and a second voltage converter unit, the third filter unit is connected to the output of the DC power module, the full bridge switch unit is connected to an output of the third filter unit is connected, the second voltage converter unit is connected to an output of the full bridge switch unit, and the full bridge switch unit is connected to a second PWM controller configured to control the full bridge switch unit.

A multifunctional plasma surgical system according to any one of claims 1 to 8, wherein the plasma cutting head comprises a plasma handle, a front of the plasma handle is provided with a cutting bar mounting, the plasma handle is provided with a power line mounting, a water inlet pipe and a water suction pipe, a front of the cutting bar assembly has a working electrode, one end of the power line assembly is connected to the plasma output interface, the other end penetrates through the inside of the plasma handle and the inside of the cutting bar assembly to connect to the working electrode, and one end of the water inlet pipe and one end of the water suction pipe should be connected to the liquid flow control module, and the other end of the water inlet pipe and the other end of the water suction pipe should penetrate the inside of the plasma handle and the inside of the cutter bar assembly, and reach the front of the cutter bar assembly.

A multifunctional plasma surgical system according to any one of claims 1 to 8, wherein the jet cutting head comprises a plasma jet handle, a front of the plasma jet handle is provided with a cutting head mounting, the plasma jet handle is provided with power supply wiring, an air inlet pipe and a negative compressed air suction line, the cutting head mounting is internal equipped with a high voltage electrode and a ground electrode, one end of the power supply wiring is connected to the plasma jet output interface and the other end penetrates the inside of the plasma jet handle and is connected to the high voltage electrode and the ground electrode, one end of the air inlet pipe is connected to the air flow control module , the other end penetrates through the plasma jet handle and connects to the plasma duct in the cutter head assembly, one end of the negative compressed air suction line connects to the airflow control module and the other end penetrates through the plasma jet handle and connects to a suction duct on an outer wall of the cutter head assembly.

The multifunctional plasma surgical system of claim 10, wherein the cutting head assembly includes a tubular insulating outer wall, the insulating outer wall is provided with an insulating dielectric pipe inside, and the plasma channel is disposed within the insulating dielectric pipe and passes through the front and rear sides of the insulating dielectric pipe. pipe penetrates; the high-voltage electrode is a needle-shaped high-voltage electrode, the grounding electrode is an annular grounding electrode, the needle-shaped high-voltage electrode is placed in the plasma channel of the insulating dielectric pipe, the annular grounding electrode is slid over an outer wall of the insulating dielectric pipe, the annular grounding electrode is in front of the needle-shaped high-voltage electrode , a front side of the needle-shaped high-voltage electrode is located at a certain distance from a rear side of the annular ground electrode; or the high-voltage electrode is a high-voltage annular electrode, the grounding electrode is an annular grounding electrode, the high-voltage annular electrode and the high-voltage annular electrode are slid over the outer wall of the insulating dielectric pipe, the high-voltage annular certain distance from the back of the annular ground electrode.